Læknablaðið - 15.04.1994, Blaðsíða 31
LÆKNABLAÐIÐ 1994; 80: 149-153
153
comparable in symptom and clinical parameters.
Global assessment of symptoms showed that in
the sucralfate group 34 improved (68%), 11 were
unchanged and 5 were worse. In the placebo group
31 improved (69%), 11 were unchanged and 3
were worse. There was no statistical difference
between the groups. The three week course of
sucralfate 1 gm q.i.d. in patients with non-ulcer
dyspepsia did not show symptomatic improvement
over placebo.
HEIMILDIR
1. Jones R, Lyderard SE. Prevalence of symptoms of
dyspepsia in the community. Lancet 1989; I: 47-51.
2. Jones R, Lyderard SE, Hobbs FDR, Kenkre JE,
Williams EI, Jones SJ. Dyspepsia in England and
Scotland. Gut 1990; 31: 401-5.
3. Tibblin G. Introduction to the epidemiology of
dyspepsia. Scand J Gastroenterol 1985; 20/Suppl 109:
29-33.
4. Nyren O, Adami HO, Gustafsson S, Lööf L,
Nyberg A. Social and economic effects of non ulcer
dyspepsia. Scand J Gastroenterol 1985; 20/Suppl 109:
41-5.
5. Veldhuyser van Z, Tyfgat KMAJ, Jalak S, Goodacre
RL, Hunt RH. Can gastritis symptoms be evaluated in
clinical trials? An overview of treatments of gastritis,
non ulcer dyspepsia and camphylobacter-associated
gastritis. Clin Gastroenterol 1989; 11: 496-50.
6. Lööf L, Adami HO, Agenas T, Gustafsson S,
Nyberg A, Nyren O. The diagnosis and therapy
survey October 1978-March 1983, health care
consumption and current drug therapy in Sweden
with respect to the clinical diagnosis of gastritis.
Scand J Gastroenterol 1985; 20/Suppl 109: 35-9.
7. Thors H, Sigurðsson H. Oddsson E, Þjóðleifsson B.
Könnun á notkun magasárslyfja meðal Islendinga.
Læknablaðið 1994. 80: 3-11.
8. La Broody S. The treatment of non ulcer dyspepsia.
In: Wasfell C, Lance P. eds. Cinieditine: The
Westminster Hospilal Symposium. London: Churchill
Livingstone, 1978: 131-40.
9. Lance P, Filipe Ml, Schiller KFR, Wastell C.
Cimetidine for non ulcer dyspepsia (Abstract).
Gastroenlerology 1981; 80: 1203.
10. Bendtsen F, Danö P, Guldhammer B, Remvig L,
Krogsöe O. Cimetidinebehandling af röntgennegative
dyspepsi. Ugeskr Læger 1983; 145: 3090-3.
11. Kelbæk H, Linde J, Eriksen J, Mungaard S,
Moesgaard F, Bonnevie O. Controlled clinical trial
of treatment with cimetidine for non-ulcer dyspepsia.
Acta Med Scand 1985; 217: 281-7.
12. Otthard R, Bodemar G, Brodin U, Jonsson KA.
Treatment with cimetidine, antacid or placebo in
patients with dyspepsia of unknown origin. Scand J
Gastroenterol 1988; 23: 7-18.
13. Delattre M, Malensky M, Prinzie A. Symptomatic
treatment of non ulcer dyspepsia with cimetidine.
Curr Ther Res 1985; 37: 980-91.
14. Talley NJ, McNeiI D, Hayden A, Piper W.
Randomized double-blind, placebo-controlled
crossover trial of cimetidine and pirenzepine in non
ulcer dyspepsia. Gastroenterology 1986; 91: 149-56.
15. Saunders JBH, Oliver RJ, Higson DL, et al.
Dyspepsia incidence of non ulcer disease in a
controlled trial of ranitidine in general practice. Br
Med J 1986; 292: 645-8.
16. Nyren O, Adami HO. Bates S, Bergström R,
Gustafsson S, Lööf L. Absence of therapeutic benefit
from antacids or cimetidine in non-ulcer dyspepsia. N
Engl J Med 1986; 314: 339-43.
17. Kairakuoma MI, Hentile R, Alavaikko M, Kellosalo
J, Stahlberg M, Jalovaara P. Sucralfate versus placebo
in treatment of non-ulcer dyspepsia. Am J Med 1987;
83/Suppl 3B: 51-5.
18. McCarthy DM. Drug therapy: Sucralfate. N Engl J
Med 1991; 325: 10Í7-25.
19. Young MJ, Bresnitz EA, Strom BL. Sample size
nomograms for interpreting negative clinical studies.
Ann Int Med 1983; 99: 248-51.
20. Sonnenberg A. Geographical and temporal variations
in the occurrence of peptic ulcer disease. Scand J
Gastroenterol 1985; 2/Suppl 110: 11-24.
21. Bonnevie O. Future research, methodological aspects.
Scand J Gastroenterol 1987; 22/Suppl 128: 114-6.
22. Oddsson E, Binder V, Thorgeirsson T, Jonasson
TA, Gunnlaugsson O, Wulff M. A prospective
comparative study of clinical and pathological
characteristics in Icelandic and Danish patients with
gastric ulcer, duodenal ulcer and X-ray negative
dyspepsia. Scand J Gastroenterol 1978; 13: 489-95.
23. Kristinsson KG, Þjóðleifsson B, Sigvaldadóttir E,
Jensson O, Wadström T. Mælingar á mótefnum gegn
Helicobacter pylori í Islendingum. Læknablaðið 1992,
78/Fylgirit 21: 60.
24. Tytgat GNJ. Clinical efficacy of sucralfate in refiux
oesophagitis. Comparison with cimetitine. Am J Med
1987; 83/Suppl 3B: 38-42.
25. Williams RM, Orlando RC, Bozynski EN, et al.
Multicenter trial of sucralfate suspension for the
treatment of reflux oesophagitis. Am J Med 1987;
83/Suppl 3B: 61- 6.