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Læknablaðið - 01.04.1978, Page 16

Læknablaðið - 01.04.1978, Page 16
50 LÆKNABLAÐIÐ In view o£ this, we are of the opinon that differences in endogenous factors immunologi- cal on one hand and chemical and metabolic in the motor neuron system on the other, account for the different clinical pictures, regarding the extension of symptoms and signs and the rate of disease progression. Regarding long survial time in M.N.D. slovv progression of initial symptoms and Iate clini- cal apperance of extension of the disease process to other parts of the motor neuron system, appear to be decisive. We have na explanation for longevity in M.N.D. in Iceland which appears genuine even if discrepan- cies in classification are allowed for. Further studies are being conducted. HEIMILDIR. 1. Ask-Upmark, E.: Amyotrophic laterai sclero- sis observed in 5 persons after gastric resec- tion. Gastroenterology 15:257-259, 1950. 2. Ask-Upmark, E.: Presipitating factors in the pathogenesis of amyotrophic lateral scelerosis. Acta med.scand. 170:717-723, 1961. 3. Barris, R.W.: Pancreatic adenoma (hyperin- sulinism) assosiatet with neuromuscular disorders. Ann.intern. Med. 38:124-129, 1953. 4. Bergmann S, og Guðmundsson K.R.: Chronic nmyotrophic lateral sclerosis. A clinical study (to be published). 5. Berry, R.G.: Chambers, R.A. Duckett, S og Terrero, R.: Clinicopathological study of juvenile amyotrophic lateral scierosis. Neuro- logy 19:312, 1969. 6. Bobowick, A.R. og Brody, J.A.: Epidemiology of motor neuron diseases. New England J. of Med. 288:1047-1055, 1973. 7. Bonduelle, M.: Amyotrophic laterai scierosis. Handbook of clinical Neurology, vol. 22. System disorders and atrophies Part 11. Eds. P.J. Vinken og G.W. Bruyn, North Holland Publis- hing Co. 1975 281-338. 8. Brain, W.R., Croft, P.B. og Wilkinson, M.: Motor neuronp disease as a manifestation of neoplasm. Brain 88:479-501, 1963. 9. Brain, Lord, Croft P. og Wilkinson, M.: The course and outcome of motor neurone disease. In F.H. Norris Jr. and L.T. Kurland eds: Motor Neurone Diseases. New York-London. Grunc and Strattion 20-27, 1969. 10. Brody J.A., W.J. Hadlow. Hotchin, J., Johnson, R.T. Koprowski. H. og Kurland L.T.: Soviet search for viruses that cause chronic neuro- logic disease in t.he USSR Science 147:114- 116, 1965. 11. Brown. I.A.: Chronic mercurialism. Cause of clinical syndrome of amyotrophic lateral sclerosis. Arch. Ncurology 72:674, 1954. 12. Brown. J.C. og Kater. R.M.H.: Pancreatic function in patients with amyotrophic lateral sclerosis. Neurologji 19:185-189. 1969. 13. Brownell. B., Opnenheimer, D.R. og Hughes, J.T.: The central nervous system in motor neuron disease. J. Neurol. Ncurosurg. Psychiat. 33:338-357, 1970. 14. Campbell, A.M.G., Williams, E.R. og Barltorp D.: Motor neurone disease and exposurc to lead. J. Neurol. Neurosurg. Psychiat. 33:877- 885, 1970. 15. Castalano Jr., L.W.: Herpes virus hominis antibody in multiple sclerosis and amyotrophic lateral sclerosis. Ncurology 19:1101-1106, 1972. 16. Emery A.E.H.: The nosology of spinal muscu- lar atrophies. Second Intcrnational Congress on muscle Disease (International Congress series No. 237). Amsterdam, Excerpta Medica 1971 p. 48. 17. Epinosa, R.E., Okihiro, M.M., Mulder, D.W. og Sayre G.P.: Hereditary amyotrophic lateral sclerosis. A clinical and pathologic report with comments on classification. Neurology 12: 1-7, 1962. 18. Friedman, A.P. og Frcedman D.: Amyotrophic lateral sclerosis. J. nerv.ment. Dis. 3:1-18, 1950. 19. Goldblatt D.: Motor neuron disease historical introduction. In F.H. Norris and L.T. Kurland eds.: Motor neuron diseases, New York- London Grune and Stratton 335-346, 1969. 20. Guðmundsson, K.R.: The prevalence of some neurological diseases in Iceland. Acta neurol. Scand. 44:57-69. 1968. 21. Hirano, A., Malamud, N., Kurland, L.T. og Zimmermann, H.M.: A review of the patho- logic findings in amyotrophic lateral sclerosis In F.H. Norris and L.T. Kurland eds.: Motor Neuron Diseases, New York-London Grune and Stratton 335-346. 1969. 22. IIornabrook.R.W.: Amytrophic lateral sclerosis in New-Guinea. Handbook of Clinical Neuro- logy Vol. 22 System Disorders and Atrophies Part 11, Eds. P.J. Vinken og G.W. Bruyn, North-HoIIand Publishing Co. 1975 349-352. 23. Jellifee, S.E.: The amyotrophic lateral sclerosis syndromc and trauma. J. Nervment. Dis. 82: 415-435, 532-550. 1935. 24. Jokelainen, M.: The epidemiology of amyotro- phic latcral sclerosis in Finland. A study based on the Death Certificates of 421 patients. J. Ncurol. Sciences 29:55-63, 1976. 25. Kugelberg, E. og Wclander L.: Heredofamilial proximal spinal muscular atrophy simulating muscular distrophy. Arch. Neurol. Psycliiat. 75:500-509, 1956. 26. Kurland, L.T. og Brody. J.A.: Amyotrophic lateral sclcrosis: Guam type. Handbook of Clinical Neurology. Vol. 22. System Disorder and Atrophies. Part 11. Eds. P.J. Vinken og G.W. Bruyn. North-Holland Publishing Co. 1975, 349-352. 27. Kurland, L.T., Choi, N.W. og Sayre G.P.: Implications on incidence and geographic pat- tern on the classification of amyotrophic lateral sclerosis. In. Motor Neurone Diseases, Ncw York-London, Grune-Stratton. 28-50, 1969. 28. Kurland, L.T. og Mulder, D.W.: Epidemiologic invest.igations of amyotrofic Iateral sclerosis I. Preliminary report on geographic distribu- tion with special reference on the Mariana
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