Læknablaðið - 01.04.1978, Page 83

LÆKNABLAÐIÐ
95
HBsAb, by the counterimmunoelectrophoresis
technique (CIEP). Eight blood donors were
detected with HBsAg, while only three were
found to have the antibody HBsAb (Table 1
and 2). 95% of the blood donors are males
80% of whom are in the age group 18—39
years. The frequency among blood donors is
1/1394 or 0.072. which is the iowest found
among Scandinavian and North European
donor populations investigated by the same or
s'milar technique.
Eight hospital patients among 613 were found
I-IB-Ag positive and three of them were forei-
gners. One HBcAg positive was found among
588 individuals suspected of chromosomal aber-
mtion, anDrox. half of whom were in hospital
o- liv'ng in institutions (53). The testing of
500 sampies from Icelanders by more sensitive
methods (RIA) has indicated. that the present
estimate of the frequency of the HBsAg, and
in n-’"ticular its antibody, is too low. Subtyping
was done on sera from eight individuals and
all f-nind to be of the ad (D) subtype.
Þakkarorð. Við þökkum samstarfsmönn-
um okkar. bæði þeim sem nefndir eru áður
og starfsiiði siúkrahúsanna, sem sýnt hef-
ur þessum rannsóknum áhuga og aðstoðað
okkur á ýmsan hátt. Við þökkum einnig
heilbrigðismálaráðuneytinu og Stjórnar-
nefnd ríkisspítalanna skilning og stuðning
við að koma þessum rannsóknum í gang.
HEIMILDIR:
1. Banke. O.. Dybk.iaer. E.. Nordenfelt, E„
Reinicke. V.: Australia-antigen and anti-
bodv in 10.000 Danish blood donors. Lancet
I. 860^61. 1971.
2. Rlumberg. B.S., Alter. H.J.. Visnich. S.:
A ,.new“ antigen in leukemia sera.
•T.A M.A. 191. 541-546, 1965.
3. Biumberg. B.S.: Samvinna og bréfasam-
band 1974 og 1975.
4. Brummelhuis. H.G.J.: Technical aspects
and results of the determination of hepa-
titis associated antigen (HAA) and anti-
bodv. Vox Sang (Basel) 19, 228-33, 1970.
5. Couroucé, A.M., Holland, P.V., Muller,
J.Y.,Soulier, J.P.: HBC Antigen Subtypes.
Proceedings of the International Workshop
on HBS Antigen Subtypes, held at the
Centre National de Transfusion Sanguine,
Paris, April 14-18. 1975. S. Karger, Basel,
Switzerland 1976.
6. Gocke, D.J. & Howe, C.: Rapid detection
of Australia antigen by counterim-
munoelectrophoresis. J. Immunol. 101/,
1031-32, 1970.
7. Helske, T.: Carriers of Hepatitis B Anti-
gen and Transfusion Hepatitis in Fin-
land. Scand. J. Haemat. Supplementum No
22. Munksgaard. Copenhagen 1974.
8. Helske, T. and Nevanlinna, H.R.: Preli-
minary Communication: Familial Accumu-
lation of Carriers of Au antigen. J. Med.
Genet. 10. 270-272, 1973.
9. Iwarson. S„ Lindholm. Annika, Lundin.
P„ Hermodsson. S.: Hepatitis-assosiated
antigen and antibody in Swedish blood
donors. Vnx Sang. (BaseD 22, 501-09. 1972.
10. Jónasson. .T.L.: Hepatitis B antigen. Lækna-
hl. 63. 3-19. 1977.
11. Melnick. J.L., Hollinger. F.B.: Progress in
liver diseases. IV. 345-365, Grune and Strat-
ton, New York. 1972.
12. Skinhöi. P.: Epidemiology of Hepatitis B
antigen and antibody in hospital patients
in Conenhagen. Scand J Infect Dis. 7.
85-89. 1975.
13. Skinhöi. P.: Samvinna og bréfasamband
1975 og 1976.
14. Solaps. M.H.: Frequencv of the Australia-
SH antigen and antibody among Nor-
wegian blood donors. Scand J Haemat.
7. 506-08, 1970.
15. Wallace, J., Milne, G.R., Barr, A.: Total
screening of blood donations for Australia
(Hepatitis Associated) antigen and its
antibody. Brit. med. J. 1, 663-64, 1972.
16. WHO. Advances in viral hepatitis. Techni-
cal Report Series, No 602. Geneva, 1977.