Læknablaðið - 15.03.1990, Blaðsíða 30

150
LÆKNABLAÐIÐ
rated on a Clinical Global Impressions scale. Side
effects were judged by a modified UKU scale.
Sedation was scored on a four point scale.
All patients responded to treatment within 24 hours
as judged by the CGI-scale, but the only group
large enough to give statistically significant results
was the one with the diagnoses 296 and 296.2.
Side effects were minor. Sedation was seen one
to two hours after the first injection, reaching
maximum after eight hours.
The study demonstrated that zuchlopenthixol
acetate in Viscoleo®is effective in initiating
treatment of severely disturbed psychotic patients
and must be considered a useful addition to other
neuroleptic drugs.
HEIMILDIR
1. Amidsen A, Nielsen MS, Dencker SJ. Zuchlopenthixol
acetate in Viscoleo®-a new drug formulation. Acta
Psychiatr Scand 1987; 75: 99-107.
2. Lövert AC, Rasmussen EM. Akut psykotiske
tilstande behandlet med zuchlopenthixol-acetat 5% i
Viscoleo®(Cisordinol-Acutard). En global vurdering af
den kliniske effekt. I prentun (Lundbeck).
3. Amidsen A, Aaes-Jörgensen T, Thomsen NJ, Madsen
VT og Nielsen MS. Serum,concentrations and clinical
effect of zuchlopenthixol acetate in Viscoleo®.
Psychopharmacology 1986; 90: 412-6.
4. Guy W. ECDEU assessment manual for
psychopharmacology. DHEW public. No.(ADM) 76-
338, NIMH, Rockvilie, Md, USA, 1976.
5. Dencker SJ, Ahlfors UG, Bech P, Elgen K,
Lingjærde O. Classification of side effects in
psychopharmacology. Pharmacopsychiatry 1986; 19:
40-2.
6. Lingjærde O. Psykofarmaka. Oslo: Tanum-Norli 1976.
7. Neborski R, Janowsky D, Munson E, Depry D. Rapid
treatment of acute psychotic symptoms with high- and
low-dose haloperidol. Arch Gen Psychiatry 1981; 38:
195-9.
8. Donlon PT, Hopkin JT, Tupin JP, Wicks JJ , Wahba
M, Meadow A. Haloperidol for acute schizophrenic
patients. Arch Gen Psychiatry 1980; 37: 691-5.
9. Höjelse F, Blom L. Lokal vævsbeskadigelse efter
intramuskulær injektion af neuroleptika. Nord Psyk
Tidsskr 1987; 41: Suppl. 16, 37-9.