Læknablaðið - 15.01.1991, Blaðsíða 13

LÆKNABLAÐIÐ
5
af sjúklingum með jámofhleðslu 450 ml
vikulega þar til B-blóðrauði var kominn niður
fyrir 110 g/1. Jámbirgðir vom metnar og
leiðréttar með 4 mg á dag vegna jámfrásogs
meðan á blóðtökutímabili stóð (23).
Table 1. Response rates according to group, residence, and
sex.
Group-Residence Response Investigated Response Investigated
Males (n=1500) Females (n=1500)
A. Urban .. (73.5%) (63.9%) (74.8%) (71.3%)
A. Rural ... (65.6%) (59.5%) (73.1%) (56.9%)
Males (n=669) Females (n=571)
B. All urban (63.4%) (55.6%) (65.7%) (57.6%)
Response is the percentage of invited individuals examined at the Heart
Preventive Clinic in Reykjavik in cardiovascular studies. Investigated is
the percentage of individuals in whom B-Hemoglobin B-RBC, B-MCV,
S-lron, S-TIBC, and S-Ferritin were obtained.
NIÐURSTÖÐUR
Svömn við boði um að koma í skoðun er
sýnd í töflu 1. Svömn í hópi A var svipuð í
aldursflokkunum 35-65 ára en aðeins lægri
meðal yngri og eldri einstaklinga. Meðalaldur
karla í hópi A var 51 ár á Reykjavíkursvæði,
en 51,7 ár í Ámessýslu, 49,6 ár fyrir konur á
Reykjavíkursvæði, en 50,6 ár í Ámessýslu.
Meðalaldur karla í hópi B var 36,7 ár og
kvenna 37,0 ár.
Meðaltöl og dreifing mæligilda fyrir jám
er sýnt í töflu 2 fyrir hóp A og í töflu 3
fyrir hóp B. Karlmenn á Reykjavíkursvæði
höfðu marktækt minnkað B-RBC, aukið
B-MCV, hærra S-TIBC, og lægra S-
ferritín en karlmenn í Ámessýslu. Konur á
Reykjavíkursvæði höfðu marktækt lægra B-
Table 2. Means, medians, and distributions of laboratory measurements relevant to iron status in Group A.
Urban Rural
Parameter Mean Median 95% range Mean Median 95% range p<0.05
Males:
B-Hemoglobin, g/L 151.0 151 133-169 151.9 152 134-170 No
B-RBC, 10'2/L 4.87 4.88 4.15-5.56 4.94 4.92 4.28-5.56 Yes
B-MCV, fL 92.2 92.1 84.5-101.8 91.1 91.0 84.1-97.9 Yes
S-lron, /tmol/L 18.1 18 8-32 18.1 18 7-31 No
S-TIBC, /xmol/L 55.1 54 39-75 53.8 54 39-72 Yes
S-TIBC, Saturation, % .... 33.7 33.3 14-62 34.3 33.3 16-61 No
S-Ferritin,/rg/L 126 135 21-600 169 170 31-760 Yes
Females:
B-Hemoglobin, g/L 134.3 135 112-154 137.2 137 120-157 Yes
B-RBC, 10I2/L 4.35 4.35 3.67-4.96 4.44 4.44 3.78-5.10 Yes
B-MCV, fL 91.8 91.8 81.5-101.0 91.4 91.4 84.0-99.7 No
S-lron, /zmol/L 16.7 16 6-32 17.8 17 7-33 Yes
S-TIBC, /tmol/L 56.5 57 39-81 56.5 54 39-78 No
S-TIBC, saturation, % 30.4 29.2 9-62 32.2 31.7 11-61 Yes
S-Ferritin, /jg/L 52.1 50 9-378 64.3 62 13-520 Yes
The means are arithmetic means except for S-Ferritin were geometric means are used due to the skewed distribution of values.
Arithmetic means for S-Ferritin (/imol/L) were 171 in urban i males, 227 in rural males, 83 in urban females, and 100 in rural females.
The 95% ranges were dertermined with the percentile row method (23). The last column (p<0.05) indicates whether the difference between means of rural and urban groups is statistically significant at the 5% level.
Table 3. Means, medians, and distributions of laboratory measurements relevant to iron status in Group B.
Males Females
Parameter Mean Median 95% range Mean Median 95% range
B-Hemoglobin, g/L......................... 150.9 151 133-168 131.2 132 110-151
B-RBC, 1012/L............................. 4.97 4.96 4.33-5.59 4.33 4.31 3.72-4.95
B-MCV, fL.................................... 91.0 90.8 84.5-98.8 90.4 90.6 80.1-98.9
S-lron, jtmol/L.............................. 17.9 17 5-35 14.8 15 3-32
S-TIBC, pmoVL................................ 47.4 48 30-66 50.3 51 30-75
S-TIBC, saturation, %........................ 39.2 36.1 10-92 30.9 29.6 5-71
S-Ferritin,/ig/L.......................... 125.2 136 19-537 30.4 30 4-180
See footnote for Table 2. The arithmetic means for S-Ferritin were 165 and 45 /imol/L for males and females respectively.