Læknablaðið - 15.01.1992, Blaðsíða 23

LÆKNABLAÐIÐ
21
hyperthyroidism. One patient had MEA-I and
parathyroid adenoma. Both hyperplasia cases were
of the chief cell type.
During the 5-year period 1985-1989 a total of 64
patients (54 females, 10 males) were operated
on in Iceland and had histologically proven
hyperparathyroidism, 55 patients (86%) had
adenoma, 9 patients (14%) had hyperplasia.
This corresponds to 5.2 operations per 100.000
inhabitants per year. No parathyroid carcinoma
was diagnosed during the study period.
In conclusion, as we find in our material negligible
operative complications and a high surgical success
rate, we recommend a surgical treatment of all
hyperparathyroid patients except in cases where
contraindications for surgery are to be found.
HEIMILDIR
1. Stevenson JC. Lynn JA. Time to end a conservativc
treatment for mild hyperparathyroidism. Br Med J
1988; 296: 1016-7.
2. Pumell DC, Scholz DA, Smith LH, et al. Treatmenl
of primary hyperparathyroidism. Am J Med 1974;
56: 800-9.
3. Pak CYC, Stewart A, Kaplan R, Bone H, Notz C,
Browne R. Photon absorptiometric analysis of bone
density in primary hyperparathyroidism. Lancet 1975;
2: 7-8.
4. Heath DA, Wright AD, Bames AD, Oates GD,
Dorricott NJ. Surgical treatment of primary
hyperparathyroidism in the elderly. Br Med J 1980;
280: 1406-8.
5. Palmér M, Adami H-O, Bergström R, Ákerslröm
G, Ljunghall S. Mortality after surgcry for primary
hyperparathyroidism: a follow-up of 441 patients
operated on from 1956 to 1979. Surgery 1987: 102:
1-7.
6. Malmeus J. Granberg P-O. Halvorsen J, Ákerslröm
G, Johansson H. Parathyroid surgery in Scandinavia.
Acta Chir Scand 1988; 154: 409-13.
7. Famebo L-O, Trigonis C, Forsgren L, Granberg
P-O, Hamberger B. Surgery for primary
hyperparathyroidism. Experience with 400 parients
during 10 years (1972-1981). Acta Chir Scand 1984;
520: 11-6.
8. Tarazi R, Caldwell B, Esselstyn CB, Coccia MR.
Parathyroidectomy for primary hyperparathyroidism:
Early discharge. Surgery 1984: 96: 1158-61.
9. Brothers TE, Thompson NW. Surgical treatment of
primary hyperparathyroidism in elderly patients. Acta
Chir Scand 1987; 153: 175-8.
10. Lafferty FW, Hubay CA. Primary
hyperparathyroidism. A reveiew of the long-term
surgical and nonsurgical morbidities as a basis for
a rational approach to treatment. Arch Intem Med
1989; 149: 789-96.
11. Rudberg C, Ákerström G, Palmér M, et al. Late
results of operation for primary hyperparathyroidism
in 441 patients. Surgery 1986; 99: 643-51.
12. Sivula A, Ronni-Sivula H. Observations on 334
patients operated on for primary hyperparathyroidism.
Ann Chir Gynaecol. 1985; 74: 66-73.
13. Saaka MB, Sellke FW, Kelly Tr. Primary
hyperparathyroidism. Surg Gyn Obst 1988; 166: 333-
7.
14. Heath H, Hodgson SF, Kennedy MA. Primary
hyperparathyroidism. Incidcnce, morbidity. and
potential economic impact in a community. N Engl
J Med 1980; 302: 189-93.
15. Rao DS. Wilson RJ, Kleerekopcr M, Parlitt AM.
Lack of biochemical progression or continuation of
accelerated bonc loss in mild asymptomatic primary
hyperparathyroidism: evidence for biphasic disease
course. J Clin Endocrinol Metab 1988; 67: 1294-8.
16. Potts, John T Jr. Managcmcnt ol' asymptomatic
hyperparathyroidism. J Clin Endocrinol Metab 1990;
70: 6: 1489-93.
17. Guðmundsson SÞ. Hyperparathyroidismus primaria.
Læknablaðið 1965; 49: 49-59.
18. Kjeld M, Eldon J, Olafsson Þ. Kalsíum, magncsíum
og fosfór í scrmi. Læknablaðið 1985; 71: 207-10.
19. Christensson T. Hcllström K, Wengle B, Alvcryd A,
Wikland B. Prevalence of hypcrcalcaemia in a health
screening in Stockholm. Acta Med Scand 1976: 200:
131-7.
20. Palmér M, Jakobson S, Ákerström G, Ljunghall S.
Prevalence of hypercalcemia in health survcy. A 14
year follow-up study of serum calcium values. Eur J
Clin Invest 1988; 18: 39-46.
21. Mundy GR, Covc DH. Fisken R. Primary
hyperparathyroidism: Changes in thc pattcrn of
clinical prescntation. Lancet 1980; I: 1317-20.
22. Kay S. The abnorntal parathyroid. Hum Pathol 1976;
7: 127-38.
23. Castleman B, Roth Sl. Tumors of the parathyroid
glands. Atlas of Tumor Pathology. Sccond Scrics,
Fascicle 14. Washington DC: Armed Forces Institute
of Pathology, 1978.
24. Black WC. Utley JR. The differential diagnosis of
parathyroid adenoma and chief cell hyperplasia. Am
J Clin Pathol 1968; 49: 761-75.
25. Saxe AW, Baier R, Tesluk H, Toreson W. The
role of the pathologist in the surgical treatmcnt ol'
hyperparathyroidism. Surg Gyn Obstcl 1985; 161:
101-5.
26. Malette LE, Tuma SN. Bergcr RE. Kirkland JL,
et al. Radioimmunoassay for the middle region of
human parathyroid hormon using an homologous
antiserum with a carboxy terminal fragmcnl of
bovine parathyroid hormon as radioligand. J Clin
Endocrinol Mctabolism 1982; 54: 1017.
27. Mannfjöldi á íslandi árið 1985-89. Hagstofa íslands.
munnlegar upplýsingar.
28. Ronni-Sivula H, Sivula A. Long-term effect ol'
surgical treatment of the symptoms of primary
hyperparathyroidism. Ann Clin Rcs 1985: 17: 141-
7.
29. Kristoffersson A, Boquist L, Holmlund D. Járhull
J. Long-term effects of surgcry for normocalcaemic
hyperparathyroidism. Acta Chir Scand 1987; 153:
331-6.
30. Rutledge R, Sliegel M. Thomas CG. Wild RE. Thc
relation of serum calcium and immunoparathormone
levels to parathyroid size and wcight in primary
hyperparathyroidism. Surgery 1985; 98: I 107-12.
31. Carlson GL, Farndon JR. Clayton B, Rose PG.
Thallium isotope scintigraphy and ultrasonography:
Comparative studies of localizalion techniques in
primary hypcrparathyroidism. Br J Surg 1990; 77:
327-9.