Læknablaðið - 15.03.1997, Blaðsíða 38

170
LÆKNABLAÐIÐ 1997; 83
In a multicentre study, 324 patients were
randomized to treatment with inogatran or in-
travenous heparin. During the first 24 hours,
the heparin treated patients had less episodes
of ischaemia, a shorter total duration of ischae-
mia and a lower proportion of patients with
ischaemia than patients receiving inogatran.
At 7 days of follow-up 35% of the heparin
treated patients had died, suffered nonfatal
infarction, refractory of recurrent angina com-
pared with 50% among inogatran treated pa-
tients (p<0.05).
Continuous ST-segment monitoring of is-
chaemia by computerized vectorcardiographic
may be used to risk stratify patients within 24
hours of hospital admission. The method is
more powerful than serial biochemical meas-
urements and may be used to evaluate the
clinical efficacy of treatment with thrombin
inhibitors.
Key words: Unstable coronary disease, vectorcardio-
graphy, risk stratification, thrombin inhibitors.
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nafni þótt þess sé ekki getið við birtingu.
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