Læknablaðið - 15.06.2006, Blaðsíða 38

KLÍNISKAR LEIÐBEININGAR / HJARTA- OG ÆÐASJÚKDÓMAR
SCORE-korti frá 2005 er markmið að ná kólest-
eróli niður fyrir 5 mmól/L og LDL-kólesteróli
niður fyrir 3 mmól/L.
Aldur
Almennt virðast leiðbeiningar forðast að taka á
þessu atriði umfram það sem fram kemur hér að
framan. Aldursviðmið hér virðast þó fara hækk-
andi og í Heart Protection Study virtust þátttak-
endur allt að 80 ára gamlir hafa gagn af meðferð
(2).
Mat á áhrifum leiðbeininganna
Reynt var að leggja mat á það hversu margir
myndu teljast í mikilli áhættu hér á landi sam-
kvæmt ofanskráðum tillögum. Tekið var mið af
gögnum Hjartaverndar fyrir karla og konur í ald-
urshópnum 35-67 ára frá árinu 2003 (tafla I).
Ef 10% áhætta er skilgreind sem mikil áhætta
myndu um það bil 14% einstaklinga í framan-
greindum aldurshópi lenda í þeim flokki þar sem
íhuga þyrfti kólesteróllækkandi lyfjameðferð. Sé
tekið mið af 50 ára og eldri myndu 60% karla og
um 9% kvenna teljast í mikilli áhættu samkvæmt
framangreindum viðmiðunargildum.
Þakkir
Hjartavernd fær þakkir fyrir að leggja til faralds-
fræðileg gögn sem íslenskt áhættumat er byggt á.
Sérstakar þakkir fær Thor Aspelund, tölfræðingur
Hjartaverndar, fyrir mikla og vandaða vinnu við
undirbúning gagna sem eru grundvöllur þessara
leiðbeininga.
Heimildir
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