Læknablaðið - 15.01.2011, Page 18

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Prevalence of food allergy in lcelandic infants during first year of life
Objective: This study is a part of EuroPrevall, an
EU-funded European food allergy project. The aim was to
evaluate the prevalence of food allergy in lcelandic infants
during their first year of life.
Material and methods: Infants (n=1,341) were
followed prospectively from birth to 12 months of age.
Questionnaires were obtained at birth and 12 months.
Children with symptoms of possible food allergy were
assessed with a skin-prick test (SPT) and specific IgE.
Food allergy was confirmed with a double-blind placebo-
controlled food challenge (DBPCFC).
Ftesults: Out of 170 symptomatic children 44 infants
(3.27%) had either positive SPT (n=21; 1.57%) or specific
IgE (n=40; 2.98%). Food allergy was confirmed in 25
(1.86%); egg allergy 1.42%, milk 0.52%, fish 0.22%, wheat
0.15%, peanuts 0.15%, and soy 0.07%. Atopic dermatitis
was diagnosed in 7.90% (n=106) and according to
questionnaires 8.80% had asthma (n=118). Positive family
history was the strongest risk factor for asthma (OR=2.12;
p<0.001) and atopic dermatitis (OR=1.90; p=0.004). Family
history influenced the relationship between predisposing
factors and allergy symptoms.
Conclusion: Our results show lower prevalence of food
allergy than previously reported in a study of lcelandic
children at two years of age. The prevalence was also
lower than reported in some other European countries and
could be explained by different genetic and environmental
factors.
Kristinsdóttir H, Clausen M, Ragnarsdóttir HS, Halldórsdóttir IH, McBride D, Beyer K, Sigurðardóttir ST
Prevalence of food allergy in lcelandic infants during first year of life. Icel Med J 2011; 97: 11-8
Key words: exem, infants, food allergy, prevalence, asthma, atopic dermatitis.
Correspondence: Sigurveig Þ. Sigurðardóttir, veiga@landspitali.is
Barst: 25. maí 2010, - samþykkt til birtingar: 9. nóvember 2010
Hagsmunatengsl: Engin
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