Læknablaðið - 15.09.2011, Blaðsíða 15
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1. Burr ML, Butland BK, King S, Vaughan-Williams E.
Changes in asthma prevalence: two surveys 15 years
apart. Arch Dis Child 1989; 64:1452-6.
2. Ninan TK, Russell G. Respiratory symptoms and atopy in
Aberdeen schoolchildren: evidence from two surveys 25
years apart. BMJ 1992; 304: 873-5.
3. Wieringa MH, Weyler JJ, Nelen VJ, et al. Prevalence of
respiratory symptoms: marked differences within a small
geographical area. Int J Epidemiol 1998; 27: 630-5.
4. Comtois P. The experimental research of Charles H.
Blackley. Aerobiologia 1995; 11: 63-8.
5. Riedler J, Eder W, Oberfeld G, Schreuer M. Austrian
children living on a farm have less hay fever, asthma and
allergic sensitization. Clin Exper Allergy 2000; 30:194-200.
6. Bjamadóttir E, Gíslason D, Gíslason Þ. Algengi bráða-
ofnæmis og astma meðal íslenskra læknanema. Lækna-
blaðið 2001; 87: 621-4.
7. Weiland SK, von Mutius E, Hirsch T, et al. Prevalence of
respiratory and atopic disorders among children in the
East and West of Germany five years after unification. Eur
Respir J 1999; 14: 862-70.
8. Bumey PG, Malmberg E, Chinn S, Jarvis D, Luczynska C,
Lai E. The distribution of total and specific semm IgE in
the European Community Respiratory Health Survey. J
Allergy Clin Immunol 1997; 99:314-22.
9. Chinn S, Bumey P, Sunyer J, Jarvis D, Luczynska C.
Sensitization to individual allergens and bronchial
responsiveness in European Community Respiratory
Health Study. Eur Respir J 1999; 14: 876-84.
10. Gíslason Þ, Gíslason D, Blöndal Þ. Astmi og
öndunarfæraeinkenni meðal 20-44 ára íslendinga.
Læknablaðið 1997; 83:211-6.
11. Kummeling I, Mills EN, Clausen M, et al. The EuroPrevall
surveys on the prevalence of food allergies in children and
adults: background and study methodology. Allergy 2009;
64:1493-7.
12. Gíslason Þ, Gíslason D, Blöndal Þ, Helgason H, Rafnsson
V. Öndunarfæraeinkenni íslendinga á aldrinum 20-44 ára.
Læknablaðið 1993; 79:343-7.
13. Gíslason D, Gíslason Þ, Blöndal T, Helgason H.
Bráðaofnæmi hjá 20-44 ára íslendingum. Læknablaðið
1995; 81: 606-12.
14. Clausen M, Kristjánsson S, Haraldsson A, Björkstén B.
High prevalence of allergic diseases and sensitization in a
low allergen country. Acta Paediatr 2008; 97:1216-20.
15. Zollner IK, Weiland SK, Piechotowski I, et al. No increase
in the prevalence of asthma, allergies, and atopic
sensitization among children in Germany: 1992-2001.
Thorax 2005; 60: 545-48.
16. Gíslason D, Gíslason Þ, Blöndal T, Helgason H. Atopy,
Hyperresponsiveness and Asthma in Icelandic Urban
Population 20-44 Years of Age. Allergy (suppl. nr. 32) 1996;
51:61.
17. Ring J, Krámer U, Scháfer T, Behrendt H. Why are allergies
increasing? Curr Opin Immunol 2001; 13: 701-8.
18. Strachan DP. Hay-Fever, Hygiene, and Household Size.
BMJ 1989; 299:1259-60.
19. von Mutius E, Vericelli D. Farm living: effect on childhood
asthma and allergy. Nat Rev Immunol 2010; 10: 861-8.
20. Þorgeirsdóttir H, Steingrímsdóttir L, Ólafsson Ö,
Guðnason V. Þróun ofþyngdar og offitu meðal 45-64 ára
Reykvíkinga á árunum 1975-1994. Læknablaðið 2005; 91:
115-21.
21. Gunnbjömsdóttir MI, Amenaas E, Gíslason Þ, et al.
Obesity and noctumal gastro-oesophageal reflux are
related to onset of asthma and respiratory symptoms. Eur
Respir J 2004; 24:116-21.
22. Ólafsdóttir IS, Gíslason T, Þjóðleifsson B, et al. C-reactive
protein is elevated in non-allergic but not allergic asthma
- a multicentre epidemiological study. Thorax 2005; 60:
451-4.
23. Gislason T, Janson C, Vermeire P, et al. Reported gastro-
oesophageal reflux during sleep and respiratory symp-
toms. A population study of young adults in three
European Countries. Chest 2002; 121:158-63.
24. Laerum BN, Wentzel-Larsen T, Gulsvik A, et al. Rela-
tionship of fish and cod oil intake with adult asthma. Clin
Exp Allergy 2007; 37:1616-23.
25. Hallsdóttir M. - www.ni.is/grodur/frjomaelingar/
samantekt - júní 2011.
ENGLISH SUMMARY
Prevalence of respiratory symptoms and use of asthma drugs are increasing among young adult lcelanders
Sigurkarlsson S, Clausen M, Gíslason T, Gíslason D
Introduction: In the year 1990 the European Community Respiratory Health Survey I (ECRHS I) demonstrated that the prevalence of these diseases
was lowest in lceland (www.ecrhs.org). In order to compare the prevalence of respiratory symptoms in Reykjavik over time, a new identical cross-
sectional study was performed seventeen years later.
Material and methods: Both cohorts, were in the age group 20-44 years and randomly selected from the population in Reykjavik and suburbs. Both
answered questionnaires about respiratory symptoms, nasal allergy and use of anti-asthmatic drugs. The second cohort was part of the EuroPrevall
study (www.europrevall.org) performed in 2007.
Results: Response rate was lower in 2007 (999 or 43.2%) than in 1990 (2.903 or 80.6%).The prevalence of attacks of asthma increased over time
from 2.2% to 6.7% (p<0.0001), use of anti-asthmatic drugs increased from 2.4% to 7.2% (p<0.0001) and nasal allergy symptoms from 17.8% to
29.3% (p< 0.0001). There was an increase of all respiratory symptoms except wheezing or whistling, where the prevalence dropped from 18.0% to
14.4% (p<0.01). In the year 2007 women had more often been woken by attacks of coughing (p<0.0001), had more often attacks of asthma (p<0.05)
and were more likely to use anti-asthmatic drugs (p<0.05) than men. Attacks of asthma and the use of anti-asthmatic drugs were more common
among the younger age group in the year 2007. That was not seen in the year 1990.
Conclusion: This study provides evidence of an increase in respiratory symptoms and use of anti-asthmatic drugs over a period of 17 years from
1990 among young adult lcelanders.
Key words: Prevalence, asthma, ECRHS.
Correspondence: Davið Gíslason, davidgis@simnet.is
LÆKNAblaðið 2011/97 467