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R A N N S Ó K N
ENGLISH SUMMARY
introduction: Due to potential risk of blood transfusions, clinical
guidelines emphasize restrictive use of blood components. However,
numerous studies indicate that adherence to guidelines is often less
than optimal. Furthermore, information regarding use of blood transfu-
sion in intensive care units (ICUs) and compliance to clinical guidelines
is lacking. We studied the use of blood components in two adult ICUs in
Iceland and the compliance to clinical guidelines.
Materials and methods: All adult patients that received blood compo-
nents in both ICUs at Landspitali during 6 months in 2010 were studied.
Hematology and coagulation parameters as well as indications for
administration were compared with hospital guidelines.
Results: 202 patients (34%) received blood components, half of them
after surgery. 30% received red-blood cells (RBCs), 18% fresh frozen
plasma (FFP) and 9% platelets. The mean hemoglobin value before RBC
transfusion was 87 g/L, but in one third of cases it exceeded 100 g/L.
FFP was transfused at a normal prothrombin time in 9% of cases. No
coagulation parameters were available before transfusion of 5% of FFP.
Mean platelet count before transfusion of platelets was 82 x109/L and in
34% of cases it exceeded 100 x109/L.
Conclusion: one third of patients received blood components during
their ICU stay, most commonly RBCs. At least 6% of RBCs, 14% of
FFPs and 33% of platelets were not transfused according to recent
guidelines at Landspítali. Although our results are in line with findings of
other studies it appears that the use of blood components in Icelandic
ICUs can be improved.
key words: Blood transfusion, intensive care unit, red blood cells, fresh frozen plasma, platelets, transfusion clinical guidelines.
Correspondence: Gísli H. Sigurðsson, gislih@landspitali.is
1Departments of Anaesthesia & Intensive Care and 2Surgery, and 3Blood Bank, Landspítali University Hospital, 4Faculty of Medicine, University of Iceland
inappropriate use of blood components in critical care?
oddason KE1,2,4, Gudbjartsson T2,4, Gudmundsson S3,4, Karason S1,4, Hreinsson K1, Sigurdsson GH1,4
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