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Heimildir
Barst til blaðsins 2. apríl 2018, samþykkt til birtingar 25. júní 2018.
Helga Rún Garðarsdóttir1
Linda Ósk Árnadóttir1
Jónas A. Aðalsteinsson1
Hera Jóhannesdóttir1
Sólveig Helgadóttir4
Þórdís Jóna Hrafnkelsdóttir2,3
Arnar Geirssson5
Tómas Guðbjartsson1,3
Introduction
The aim of this study was to evaluate the
outcome of coronary artery bypass grafting
(CABG) in women compared to men, with focus
on short-term and long-term complications, 30
day mortality and survival.
Materials and methods
This was a retrospective study on all CABG pati-
ents operated in Iceland between 2001 and 2013.
Clinical information was gathered from hospital
charts and survival data was obtained from the
National Statistics in Iceland. Overall survival
was estimated with the Kaplan- Meier method.
Logistic and Cox regression analysis were used
to identify predictors of operative mortality and
long-term survival. Mean follow-up was 6.8
years.
Results
Of 1755 patients 318 were women (18%). Women
were on average four years older than men at
the time of operation (69 vs. 65 yrs, p<0.001).
Female patients had a higher incidence of
hypertension (72 vs. 64%, p=0.009) and their
EuroSCOREst was higher (6.1 vs. 4.3, p<0.001).
The prevalence of diabetes, dyslipidemia and
the extent of coronary artery disease was
comparable between groups. The rate of short-
-term complications, both minor (53% vs. 48%,
p=0.07) and major (27% vs. 32%, p=0.2), was
similar and operative mortality for women was
not statistically different from males (4% vs. 2%,
p=0.08). Female gender was neither found to be
a predictor of 30-day mortality (OR 0.99; 95%-CI:
0.98-1.01) nor survival (HR 1,08; 95%-ÖB: 0,82-
1,42).
Conclusions
The number of women that undergo CABG
is low and they are four years older than men
when operated on. As is the case with men,
outcome following CABG in Iceland is very good
for women, their overall five-year survival being
87%.
Outcome of coronary artery bypass grafting in women in Iceland
ENGLISH SUMMARY
Departments of 1Cardiothoracic Surgery and 2Cardiology, Landspitali University Hospital, Iceland, 3Faculty of Medicine, University of Iceland, 4Deparment of Anesthesia and Intensive Care,
Akademiska Hospital, Uppsala, Sweden, 5Cardiothorac Surgery, Yale New Haven Hospital, USA.
Key words: gender, coronary artery disease, complications, curvival, MACCE, CABG.
Correspondence: Tómas Guðbjartsson, tomasgud@landspitali.is
340 LÆKNAblaðið 2018/104