Læknaneminn - 01.10.1989, Page 22

Læknaneminn - 01.10.1989, Page 22
hyggja var sjúklingurinn með alnæmisveiru mótefnavaka og mótefni á þessum tíma. Það sást við rannsókn á sermi: Sérstakt ELISA próf þar sem prófað er fyrirp24 mótefnavaka var jákvætt. Ákveðið ELISA próf þar sem byggt er á endurröðunar- (recombinant) DNA tækni var jákvætt með tilliti til mótefna. Hins vegar voru ELISA-OrganonR og Westem blot próf neikvæð í fyrstu legunni en reyndust síðar jákvæð. Western blot eða hliðstæð próf eru yfirleitt notuð til þess að staðfesta sýkingu, ef ELISA próf er jákvætt. Mjög misjafnt er hveru fljótt einstaklingur myndar mótefni eftir alnæmisveirusýkingu. Nefna má að sýnt hefur verið fram á sýkingu nokkrum árum áður en ELISA próf verður jákvætt (18). * * * MyndirerueftirJóhannesBjömsson. Myndtextar eru eftir Jóhannes Bjömsson og Bjarna Agnarsson. Eg þakka Haraldi Briem, Sigurði Guðmundssyni og Jóhannesi Bjömssyni fyrirgagnlegar ábendingarog yfirlestur greinarinnar. Heimildir 1. Bricaire F et al. Adrenocortical lesions and AIDS (Letter). Lancet 1988;16. april; 1 (8590):881. 2. Came CA. ABC of AIDS. Neurological Manifestations. British Medical Joumal 1987, Vol 294; 30 may: 1399-1401. 3. CDC. Update on Acquired Immune Deficiency Syndrome (AIDS)-United States. Morbidity and Mortality Weekly Report 1982; 31: 507-514. 4. Fauci AS, Lane HC. The Acquired Immunodeficiency Syndrome (AIDS). In: Harrison’s Principles of Internal Medicine 1987. Eleventh edition (ed. Braunwald E, Isselbacher KJ, Petersdorf RG, Wilson JD, Martin JB, Fauci AS). McGraw-Hill Book Company, p. 1392-1396. 5. Gerberding JL. Diagnosis and Management og Cerebral Toxoplasmosis in Patients with Acquired Immunodeficiency Syndrome. In: Contemporary Issues in Infectious diseases VOL. 7: Parasitic Infections 1988 (ed. Leech JM, Sande MA, Root RA) Churchill Livingstone, p. 271-284. 6. Gillin JS, Shike M, Alcock N et al. Malabsorbtion and Mucosal Abnormalities of the Smal 1 Intestine in the Acquired Immunodeficiency Syndrome. Annals of Intemal Medicine 1985; 102: 619-622. 7. Gold JWM. Infectious complications in patients with HIV infection. AIDS 1988; 2: 327-334. 8. GriffinGEetal. Damagetojejunalautonomic nerves in HIV infections. AIDS 1988; 2: 379-382. 9. Haraldur Briem. Fjöldi greindra einstaklinga með alnæmi og HIV smit á íslandi, miðað við 31. desember 1988. Læknablaðið, Fréttabréf lækna 1989;7:2.tbl:4. 10. Jacobson MA, Mills J. Serious Cytomegalovirus Disease in the Acquired Immunodeficiency Syndrome (AIDS). Clinical Findings, Diagnosis andTreatment. Annalsof Internal Medicine 1988; 108: 585-594. 11. Lange DJ et al. The Neuromuscular Manifestations of Human Immunodeficiency Virus Infections. ArchNeurol. Vol45;Oct 1988:1084-1088. 12. Magnús Gottfreðsson. Alnæmi: Onæmis- fræði,meingerðoglyfjameðferð. Læknaneminn 1988; 41: l.tbl: 5-19. 13. McLeod R, Remington JS. Toxoplasmosis. In: Harrison’s Principles of Internal Medicine 1987. Eleventh edition (ed. Braunwald E, Isselbacher KJ, Petersdorf RG, Wilson JD, Martin JB, Fauci AS). McGraw-Hill Book Company, p. 791-797. 14. Millar AB. Respiratory manifestations of AIDS. British Joumal of Hospital Medicine 1988. Vol 39; 3: 204-215. 15. Mills J. Pneumocystis carinii and Toxoplasma gondii Infections in Patients with AIDS. Reviews of Infectious Diseases 1986. Vol 8, No. 6: 1001-1011. 16. Navia BA, Jordan BD, Price RW. The AIDS Dementia Complex. I. Clinical Features. Ann Neurol 1986; 19: 517-524. 17. Navia B A, Pice RW. The Acquired Immuno- deficiency Syndrome Dementia Complex as the Presenting or Sole Manifestation of Human Immunodeficiency Virus Infection. Arch Neurol. Vol 44; Jan 1987: 65-69. 18. Ranki A, Valle S, Krohn M et al. Long Latency Precedes Overt seroconversion in Sexually Transmitted Human-immunodeficiency-virus Infection. Lancet 1987. 12 sept; 2 (85599): 589-93. 19. Sigurður Guðmundsson. Viðtal í þætti í Ríkisútvarpi-sjónvarpi: Veist þú hvað alnæmi er ? 10. 20 LÆKNANEMINN 1—Vm9-42. árg.

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