Læknablaðið - 15.06.2010, Qupperneq 30

FRÆÐIGREINAR
SJÚKRATILFELLI
til þess að auka vitneskju um porfýríur og bæta
greiningu þeirra.
Heimildir
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Acute abdominal pain caused by acute intermittent porphyria
- case report and review of the literature
We describe a case of acute intermittent porphyria in a
woman who presented repeatedly with abdominal pain.
Porphyrias are caused by decreased enzyme activity in
the heme biosynthetic pathway leading to overproduction
of heme precursors if demand increases. This can cause
symptoms such as abdominal pain, nausea and vomiting,
constipation, tachycardia and hypertension. Treatment
includes removal of causative factors, administration of
carbohydrates or hemin to reduce the production of heme
precursors as well as symptomatic treatment.
Birgisdóttir BT, Arnardottir S, Asgeirsson H, Jonsson JJ, Vidarsson B.
Acute abdominal pain caused by acute intermittent porphyria - case report and review of the
literature. Icel Med J 2010; 96; 415-20.
Key words: acuíe intermittent porphyria, pathophysioiogy, epidemiology, treatment.
Correspondence; Brynjar Viðarsson, brynvida@landspitali.is
418 LÆKNAblaðið 2010/96
Barst: 3. desember 2009, - samþykkt til birtingar: 5. maí 2010
Hagsmunatengsl: Engin