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ENGLISH SUMMARY
Kawasaki Disease in lceland 1996-2005, Epidemiology and Complications
Olafsdottir HS1, Oskarsson G1-2, Haraldsson A1-2
Objective: To analyze the epidemiology of Kawasaki disease in lcelandic
children and its complications.
Methods: A retrospective analysis of all cases of Kawasaki disease and
atypical Kawasaki disease in children in lceland from 1996-2005. Chart
records were reviewed and children diagnosed at Landspítali - University
Hospital invited for a Follow up study with emphasis on heart complica-
tions.
Results: Thirty children were diagnosed with Kawasaki disease, annual
incidence was 10.7/100.000 children <5 years of age. The boy:girl ratio
was 2.3:1. All 30 children were treated with IVIG, without any major
adverse events related to the treatment. The median time from the
initial symptoms to treatment was six days (range 3-31 days). There was
Key words: Kawasaki disease, children, epidemiology, complications. Correspondence: Ásgeir Haraldsson, asgeir@iandspitaii.is
’Faculty of Medicine, University of lceland, 2Chiidrens hospital of Hringurinn, Landspitali University Hospital.
no mortality. Two children developed coronary aneurysms and three
coronary ectasia. Follow up echocardiography was preformed in 23 of the
children four to twelve years after Kawasaki disease. Two of the children
still had coronary ectasia, and six (26%) had mitral regurgitation.
Conclusions: The incidence of Kawasaki disease in lceland was comp-
arable to an earlier lcelandic study and reported incidence in the Nordic
countries. Coronary involvement during the acute phase was mild, and
all coronary aneurysm regressed. Serious cardiac complications were
not seen. Children with Kawasaki disease in lceland have favorable prog-
nosis. Interestingly, mild mitral regurgitation and coronary ectasia were
common at mid-term follow up.
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