Læknablaðið - 15.05.1988, Qupperneq 11

LÆKNABLAÐIÐ
175
patients who died suddenly and underwent autopsy.
Among men 20-39 years the age corrected incidence was
0.16 cases per 1,000 men per year during the years
1980-1984. Between January lst 1980 and December
3lst 1984 43 individuals aged 40 years and younger
suffered acute myocardial infarction in Iceland. Three
were foreigners and among the Icelandic patients two
were 17 years old, one had hypertrophic
cardiomyopathy and the other suffered chest trauma
but neither of those had any signs of coronary
atherosclerosis on coronary angiography. During the
study period 38 Icelanders in the age group 25-40 years
suffered myocardial infarction. Of those 9 (23.7%) died
before they reached hospital and 2 patients (6.9%) died
during the hospital stay. This accounts for 6.1% of the
total mortality in the age group 25-39 years during the
years 1980-1983. Risk factors were examined among the
29 patients who were admitted to hospital. Only one
patient was defined as a non smoker and 28 patients
(96.6%) smoked daily. Of the 29 hospitalized patients
there were 15 who had a first degree relative with known
coronary heart disease. Hypercholesterolemia,
hypertension and obesity were not found to be
significant risk factors. One vessel disease was most
common (59.4%) and most frequently involved the left
anterior descending artery.
HEIMILDIR
1. Heilbrigðisskýrslur 1980-1983 (Public Health in
Iceland 1980-1983). Reykjavík,
Landlæknisembættið 1986.
2. Davia JE, Hallal FJ, Cheitilin MD, Gregoratos G,
McCarty R, Foote W. Coronary artery disease in
young patients: Arteriographic and clinical review
of 40 cases aged 35 and under. Am Heart J 1974;
87: 689-96.
3. Dolder MA, Oliver MF. Myocardial infarction in
young men. Study of risk factors in nine countries.
Br Heart J 1975; 37: 493-503.
4. Bergstrand R, Vedin A, Wilhelmson C, Wallin J,
Wedel H, Wilhelmsen L. Myocardial infarction
among men below age 40. Br Heart J 1978; 40:
783-8.
5. A preliminary report from the Monica principal
investigators meeting in Geneva, 28 February to
March 1 1984.
6. Mannfjöldatölur Hagstofu íslands, Hagtíðindi
1981-1985.
7. Keys A, Fidanza F, Mariti KJ, Kimura N, Taylor
HL. Indices of Relative Weight and Obesity. J
Chronic Dis 1972; 25: 329-43.
8. Könnun Hagvangs á reykingavenjum íslendinga
1985; óbirtar niðurstöður.
9. Könnun Hjartaverndar á reykingavenjum
íslendinga 1983; óbirtar niðurstöður.
10. Björnsson OJ, Davidsson D, Olafsson O, Sigfusson
N, Þorsteinsson Þ. Survey of serum lipid levels in
Icelandic men aged 34-61 years; Reykjavik,
Hjartavernd 1978: 41-63.
11. Torfason B, Davidsson D, Sigfusson N, Björnsson
OJ. Skýrsla A XV: Líkamshæð, líkamsþyngd og
þyngdarstuðull íslenskra karla á aldrinum 34-61
árs; Reykjavik, Hjartavernd 1978.
12. Koskenuvo K, Karvonen JM, Rissanen V. Death
From Ischemic Heart Disease in Young Finns Aged
15 to 24 Years. Am J Cardiol 1978; 42: 114-8.
13. Irvine N, Ward PR, Kenmure ACF. The results of
coronary arteriography in young men after
myocardial infarction in North East Scotland. Scott
Med J 1985; 30: 8-14.
14. McKenna WJ, Chew CYC, Oakley CM.
Myocardial infarction with normal coronary
angiogram. Possible mechanism of smoking risk in
coronary artery disease. Br Heart J; 1980: 43:
493-8.
15. Hoit BD, Gilpin EA, Henning H, Maisel AA,
Dittrich H, Carlisle J, Ross J Jr. Myocardial
infarction in young patients: an analysis by age
subsets. Circulation 1986; 74: 712-21.
16. Furberg C, Romo M, Linko E, Siltanen P, Tibblin
G, Wilhelmsen L. Sudden Coronary Death in
Scandinavia. A Report From Scandinavian
Coronary Heart Disease Registers. Acta Med Scand
1977; 201: 553-7.
17. Underwood DA, Proudfit WL, Lim J, MacMillan
JP, Symptomatic Coronary Artery Disease in
Patients Aged 21-31 Years. Am J Cardiol 1985; 55:
631-4.
18. Glover MU, Kuber MT, Warren SE, Vieweg VVR,
Myocardial Infarction Before Age 36, Risk Factor
and Arteriographic Analysis. Am J Cardiol 1982;
49: 1600-3.
19. Nitter Hauge S, Erikssen J, Thaulow E, Vatne K.
Angiographic and risk factor characteristics of
subjects with early onset ischemic heart disease. Br
Heart J 1981; 46: 325-30.
20. Uhl GS, Farrel PW. Myocardial infarction in young
adults: Risk factors and natural history. Am Heart
J 1983; 105: 548-53.
21. Deanfield JE, Shea JM, Wilson RA, Horlock P, de
Landsheere CM, Selwyn AP. Direct Effects of
Smoking on the Heart: Silent Ischemic
Disturbances of Coronary Flow. Am J Cardiol
1986; 57: 1005-9.
22. Martin JL, Wilson JR, Ferraro N, Laskey WK,
Kleaveland JP, Hirshfeld JW. Acute Coronary
Vasoconstrictive Effects of Cigarette Smoking in
Coronary Heart Disease: Am J Cardiol 1984; 54:
56-60.
23. Nadler JL, Velasco JS, Horton R. Cigarette
smoking inhibits prostacyclin formation. The
Lancet; 1983: 1248-50.
24. Kaufman DW, Helmrich SP, Rosenberg L,
Miettinen OS, Shapiro S. Nicotine and carbon
monoxide content of cigarette smoke and the risk of
myocardial infarction in young men. N Engl J Med
1983; 308: 409-13.
25. Hartz AJ, Barboriak PN, Anderson AJ, Hoffmann
RG, Barboriac JJ. Smoking, Coronary Artery
Occlusion, and Nonfatal Myocardial Infarction.
JAMA 1981; 246: 851-3.
26. Tibblin G, Wilhelmsen L, Werkö L. Risk Factors
for Myocardial Infarction and Death Due to
Ischemic Heart Disease and Other Causes. Am J
Cardiol 1975; 35: 514-22.
27. Blacket RB, Leelarthaepin B, Palmer AJ, Woodhill
JM. Coronary Heart Disease in Young Men: A
Study of Seventy Patients with a Critical Review of
Etiological Factors. Aust N Z J Med 1973; 3: 39-63.