Læknablaðið - 15.04.1990, Page 9

LÆKNABLAÐIÐ
183
SUMMARY
A retrospective analysis was done on 68 patients
diagnosed to have carcinoma of the pancreas at the
Reykjavík City Hospital during the period 1974-
1983. Explorative laparotomy was most often
performed as a diagnostic procedure (89,7%). It
was not possible to evaluate the effect of new
diagnostic techniques such as ultrasonography,
computerized tomography and ERCP because they
were not available at the hospital until late in the
study period. The diagnosis was histologically
confirmed in 75% of the patients. The tumor was
most often located in the head of the pancreas
(42,5%). In 25% of the patients location of the
tumor was not reported or tumor margins could
not be determined within the gland. Metastasis
were diagnosed in 66,2% of the patients. The most
common treatment was pallative surgical bypass
of the biliary tract and/or gastro-jejunal bypass.
Mean survival of all patients was 6,4 months (192
days). One patient lived more than three years and
no patient was alive four years after diagnosis.
HEIMILDIR
1. Levin DL, Connelly RR, Devesa SS. Demographic
Characteristics of Cancer of the Pancreas: Mortality,
Incidence and Survival. Cancer 1981; 47: 1456-68.
2. Malagelada JR. Pancreatic Cancer. An Overview of
Epidemiology, Clinical Presentation, and Diagnosis.
Mayo Clinic Proc 1979; 54: 459-67.
3. Ragnarsson J, Ingimarsson GS. Heilbrigðismál 1985;
2: 14-5.
4. Moossa AR, Scott MH. Pancreatic Cancer. In
Gastrointestinal Oncology. Fielding-Priestman ed.
Castle House Publ. 1986; 139-52.
5. Williamsson RCN. Pancreatic Cancer: The Greatest
Oncological Challenge. Br Med J 1988; 296: 445-6.
6. Guðjonsson B. Cancer of the Pancreas, 50 years of
Surgery. Cancer 1987; 60: 2284-303.
7. Heuch I, Kvaale G, Jakobsen BK, Bjelke E. Use
of Alcohol, Tobacco and Coffee and the Risk of
Pancreatic Cancer. Br J of Cancer 1983; 48: 637-43.
8. Cubilla AL, Fitzgerald PO. Pancreatic Cancer (Non
Endocrine). A Review Part I. Clin Bull Mem. Sloan
Kettering Cancer Center 1978a; 8: 144.
9. McMahon B, Yen S, Trichoupoulus K, Warren K,
Nardi G. Coffee and Cancer of the Pancreas. N Engl
J Med 1981: 304: 630-4.
10. Bemarde MA, Weiss W. Coffee Consumption and
Pancreatic Cancer. Temporal and Spatial Correlation.
Br Med J 1982; 284: 400-2.
11. Cello JP. Carcinoma of the Pancreas. In
Gastrointestinal Disease. Sleizenger-Fordtran ed.
W.B. Saunders 1983; 1514-27.
12. Ingimarsson GS, Ragnarsson J, Tulinius H,
Sigvaldason H. Heilbrigðismál 1983; 2: 31.
13. Jacobsen O, Winther Olsen S, Nielsen NA. Pancreatic
Cancer in the Faroe Islands. Scand J Gastroenterol
1985; 20(9); 1142-6.
14. Trede M. The Surgical Treatment of Pancreatic
Carcinoma. Surgery 1985; 97: 28-35.
15. Carter DC. Carcinoma of the pancreas. Current
Opinion in Gastroenterology 1987; 3: 736-43.
16. Matsuno S, Sato T. Surgical treatment for carcinoma
of the pancreas. Experience in 272 patients. Am J
Surg 1986; 152: 499-503.
17. Reed K, Vose PC, Jarstfer BS. Pancreatic Cancer:
30 year Review (1947-1977). Am J Surg 1979; 138:
929-33.
18. Siegel JH, Snady H. The significance of
endoscopically placed prosthesis in the management
of biliary obstmction due to carcinoma of the
pancreas: Results of non operative decompression
in 277 patients. Am J Gastroenterol 1986; 81: 634-41.
19. Smith L, Gazet JC. Intra arterial chemotherapy for
with inoperable carcinoma of the pancreas. Ann R
Coll Surg Engl 1980; 62: 208-12.
20. Theodors A, Bukowski RM, Hewlet JS, Livingston
RB, Weick JK. Intermittent regional infusion of
chemotherapy for pancreatic adenocarcinoma. Phase I
and II pilot study. Am J Clin Oncol (CCT) 1982; 5:
555-8.
21. Shipley WU, Wood WC, Tepper JE. Intraoperative
electron beam irradiation for patients with
unresectable pancreatic carcinoma. Ann Surg 1984;
200: 289-96.
22. Greenway BA. Carcinoma of the Exocrine Pancreas:
A sex hormone responsive tumor? Br J Surg 1987;
74: 441-2.
23. Tönnesen K, Kamp-Jensen M. Anti oestrogen therapy
in Pancreatic Carcinoma: A Preliminary Report. Eur J
Surg Oncol 1986; 12: 69-70.