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Læknablaðið - 15.05.2012, Page 15

Læknablaðið - 15.05.2012, Page 15
RANNSÓKN Þakkir Þakkir fá Gunnhildur Jóhannsdóttir skrifstofustjóra og starfsfólk skjalageymslu Landspítala í Vesturhlíð fyrir aðstoð við að afla sjúkraskráa. Loks fær Axel F. Sigurðsson hjartalæknir þakkir fyrir yfirlestur og góðar ábendingar. Heimildir 1. Foley M. Cancer Screening and Diagnostics (lab manual) 2011, Reykjavik. 2. Scott WJ, Howington J, Feigenberg S, Movsas B, Pisters K. Treatment of non-small cell lung cancer stage I and stage II: ACCP evidence-based clinical practice guidelines (2nd edition). Chest 2007; 132 (3 Suppl): 234S-242S. 3. Wahbah M, Boroumand N, Castro C, El-Zeky F, Eltorky M. Changing trends in the distribution of the histologic types of lung cancer: a review of 4,439 cases. Ann Diagn Pathol 2007; 11:89-96. 4. Skuladottir R, Oskarsdottir GN, Isaksson HJ, Jonsson S, Thorsteinsson H, Gudbjartsson T. Fylgikvillar blað- námsaðgerða við lungnakrabbameini á íslandi 1999-2008. Læknablaðið 2010; 96: 243-9. 5. Thorsteinsson H, Jonsson S, Alfreðsson H, Isaksson HJ, Gudbjartsson T. Árangur lungnabrottnámsaðgerða við lungnakrabbamcini á íslandi. Læknablaðið 2009; 95:823-9. 6. Oskarsdottir GN, Skuladottir R, Isaksson HJ, Jonsson S, Thorsteinsson H, Gudbjartsson T. Forspárþættir lífshorfa eftir blaðnám við lungnakrabbameini á íslandi 1999-2008. Læknablaðið 2010; 96:251-7. 7. Gottschalk A, Cohen SP, Vang S, Ochroch EA. Preventing and treating pain after thoracic surgery. Anesthesiology 2006; 104: 594-600. 8. Wenk M, Schug SA. Perioperative pain management after thoracotomy. Curr Opin Anaesthesiol 2011; 24: 8-12. 9. De Cosmo G, Aceto P, Gualtieri E, Congedo E. Analgesia in thoracic surgery: review. Minerva Anestesiol 2009; 75: 393-400. 10. Dripps RD, Lamont A, Eckenhoff JE. The role of anesthesia in surgical mortality. JAMA. Oct 21 1961;178: 261-6. 11. Tsim S, O'Dowd CA, Milroy R, Davidson S. Staging of non-small cell lung cancer (NSCLC): a review. Respir Med 2010; 104:1767-74. 12. Brunelli A, Ferguson MK, Rocco G, Pieretti P, Vigneswaran WT, Morgan-Hughes NJ, et al. A scoring system predicting the risk for intensive care unit admission for complications after major lung resection: a multicenter analysis. Ann Thorac Surg 2008; 86:213-8. 13. Okiror L, Patel N, Kho P, Ladas G, Dusmet M, Jordan S, et al. Predicting risk of intensive care unit admission after resection for non-small cell lung cancer: a validation study. Interact Cardiovasc Thorac Surg 2012; 14:31-3. 14. Axelsson TA. Innlagnir á gjörgæslu eftir skurðaðgerðir við lungnakrabbameini. BS-ritgerð, Háskóli íslands 2011. 15. Balduyck B, Hendriks J, Lauwers P, Van Schil P. Quality of life evolution after lung cancer surgery: a prospective study in 100 patients. Lung Cancer 2007; 56:423-31. 16. Alexandersson A, Jonsson S, Isaksson HJ, Gudbjartsson T. Árangur fleyg- og geiraskurða við lungnakrabbameini á íslandi. Læknablaðið 2011; 97: 304-8. 17. Nashef SA, Roques F, Michel P, Gauducheau E, Lemeshow S, Salamon R. European system for cardiac operative risk evaluation (EuroSCORE). Eur J Cardiothorac Surg 1999; 16:9-13. 18. Licker MJ, Widikker I, Robert J, et al. Operative mortality and respiratory complications after lung resection for cancer: impact of chronic obstructive pulmonary disease and time trends. Ann Thorac Surg 2006; 81:1830-7. 19. Berrisford R, Brunelli A, Rocco G, Treasure T, Utley M. The European Thoracic Surgery Database project: modelling the risk of in-hospital death following lung resection. Eur J Cardiothorac Surg 2005; 28: 306-11. 20. Pieretti P, Alifano M, Roche N, Vincenzi M, Forti Parri SN, Zackova M, et al. Predictors of an appropriate admission to an ICU after a major pulmonary resection. Respiration 2006; 73:157-65. 21. Harpole DH Jr, DeCamp MM Jr, Daley J, Hur K, Oprian CA, Henderson WG, et al. Prognostic models of thirty-day mortality and morbidity after major pulmonary resection. J Thorac Cardiovasc Surg 1999; 117:969-79. 22. Myrdal G, Gustafsson G, Lambe M, Horte LG, Stahle E. Outcome after lung cancer surgery. Factors predicting early mortality and major morbidity. Eur J Cardiothorac Surg 2001; 20: 694-6. ENGLISH SUMMARY Intensive care unit admissions following lobectomy or sublobar resections for non-small cell lung cancer Axelsson TA, Sigurdsson Ml, Alexandersson A, Thorsteinsson H, Klemenzson G, Jonsson S, Gudbjartsson T Introduction: Following resection for non-small cell lung cancer (NSCLC), patients are usually admitted to the post-anesthesia care unit (PACU)for a few hours before admission to a general ward (GW). However, some patients need ICU-admission, either immediately post- surgery or from the PACU or GW. The aim of this study was to investi- gate the indications and risk factors for ICU-admission. Material and methods: A retrospective study of 252 patients who underwent lobectomy, wedge resection or segmentectomy for NSCLC in lceland during 2001-2010. Data was retrieved from medical records and patients admitted to the ICU compared to patients not admitted. Results: Altogether 21 patients (8%) were admitted to the ICU, median length-of-stay being one day (range 1-68). In 11 cases (52%) the rea- sons for admission were intraoperative problems, usually hypotension or excessive bleeding. Ten patients were admitted from the GW (n=4) or PACU (n=6), due to hypotension (n=4), heart and/or respiratory failure (n=4) and reoperation for bleeding (n=2). There were three ICU-read- missions. Patients admitted to the ICU were six years older (p=0.004) and more often had chronic obstructive pulmonary disease and/or coronary artery disease. Tumor size, pTNM-stage, length of operation and the ratio of patients receiving TEA (thoracic epidural anaesthesia) were similar between groups. Over two-thirds of the ICU-patients had minor complications and around half had major complications, comp- ared to 30% and 4%, respectively, for controls. Conclusion: ICU-admissions are infrequent following non-pneumo- nectomy lung resections for NSCLC, these patients being older with cardiopulmonary comorbidities. In half of the cases, admission to the ICU directly follows surgery and ICU-readmissions are few. Key words: Intensive care, post-anesthesia care unit, lung cancer, operation, thoracotomy, readmission, complications. Correspondence: Tómas Guðbjartsson, tomasgud@landspitali.is Faculty of Medicine, University of lceland, Departments of Cardiothoracic Surgery, Anesthesia and tntensive Care and Pulmonology LÆKNAblaðið 2012/98 275

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