Læknablaðið - 15.06.2013, Page 15
RANNSÓKN
Heimildir
1. Þórólfsson B, Þórðardóttir FR, Gunnarsson G, Sigurðsson
AF. Skimun fyrir áhættuþáttum skyndidauða íþrótta-
manna.Læknablaðið 2012,-98: 83-88.
2. Maron BJ, Doerer JJ, Haas TS, Tiemey DM, Mueller FO.
Sudden deaths in young competitive athletes: analysis of
1866 deaths in the United States, 1980-2006. Circulation,
2009; 119(8): 1085-92.
3. Corrado D, Basso C, Schiavon M, Pelliccia A, Thiene G.
Pre-participation screening of young competitive athletes
for prevention of sudden cardiac death. J Am Coll Cardiol.
2008; 52(24): 1981-9.
4. Corrado D, Pelliccia A, Heidbuchel H, Sharma S, Link
M, Basso C, et al. Recommendations for interpretation of
12-lead electrocardiogram in the athlete. Eur Heart J. 2010
Jan;31(2):243-59.
5. Pelliccia A, Maron BJ, Culasso F, Di Paolo FM, Spataro A,
Biffi A, et al., Clinical significance of abnormal electrocar-
diographic pattems in trained athletes. Circulation, 2000;
102(3): 278-84.
6. Lang RM, Bierig M, Devereux RB, Flachskampf FA, Foster
E, Pellikka PA, et al. Recommendations for chamber
quantification: a report from the American Society of
Echocardiography's Guidelines and Standards Committee
and the Chamber Quantification Writing Group, devel-
oped in conjunction with the European Association of
Echocardiography, a branch of the European Society of
Cardiology. J Am Soc Echocardiogr, 2005; 18(12): 1440-63.
7. Anedda F, Zucchelli M, Schepis D, Hellquist A, Corrado
L, D'Alfonso S, et al., Multiple Polymorphisms Affect
Expression and Function of the Neuropeptide S Receptor
(NPSRl). PLoS One, 2011; 6(12): e29523.
8. Corrado D. Basso C, Rizzoli G, Schiavon M, Thiene G.
Does sports activity enhance the risk of sudden death in
adolescents and young adults? J Am Coll Cardiol, 2003;
42(11): 1959-63.
9. Corrado D, Pelliccia A, Bjomstad HH, Vanhees L, Biffi
A, Borjesson M, et al. Cardiovascular pre-participation
screening of young competitive athletes for prevention
of sudden death: proposal for a common European
protocol. Consensus Statement of the Study Group of
Sport Cardiology of the Working Group of Cardiac
Rehabilitation and Exercise Physiology and the Working
Group of Myocardial and Pericardial Diseases of the
European Society of Cardiology. Eur Heart J. 2005
Mar;26(5):516-24
10. Fuller C.M. Cost effectiveness analysis of screening of high
school athletes for risk of sudden cardiac death. Med Sci
Sports Exerc, 2000; 32(5): 887-90.
11. Lichtman J, O'Rourke R, Klein A, Karliner J.
Electrocardiogram of the athlete. Alterations simulating
those of organic heart disease. Arch Intem Med, 1973;
132(5): 763-70.
12. Huston TP, Puffer JC, Rodney WM. The athletic heart
syndrome. N Engl J Med, 1985; 313(1): 24-32.
13. Zehender M, Meinertz T, Keul J, Just H. ECG variants and
cardiac arrhythmias in athletes: clinical relevance and
prognostic importance. Am Heart J, 1990; 119(6): 1378-91.
14. Weiner RB, Hutter AM, Wang F, Kim JH, Wood MJ,
Wang TJ. Performance of the 2010 European Society of
Cardiology criteria for ECG interpretation in athletes.
Heart. 2011 Oct,-97(19):1573-7
15. Rijnbeek PR, Witsenburg M, Schrama E, Hess J, Kors JA.
New normal limits for the paediatric electrocardiogram.
Eur Heart J, 2001; 22(8): 702-11.
16. Rawlins J, Bhan A, Sharma S. Left ventricular hypertrophy
in athletes. Eur J Echocardiogr, 2009; 10(3): 350-6.
17. Corrado D, Pelliccia A, Heidbuchel H, Sharma S, Link
M, Basso C, et al. Recommendations for interpretation of
12-lead electrocardiogram in the athlete. Eur Heart J, 2010;
31(2): 243-59.
18. Fagard R. The athlete's heart. Heart 2003;89:1455-1461
19. Pluim BM, Zwinderman AH, van der Laarse A, van der
Wall EE, et al. The athlete's heart. A meta-analysis of
cardiac structure and function. Circulation, 2000; 101(3):
336-44.
20. Pelliccia A, Barry M, Maron J, Spataro A, Proschan MA,
Spirito P. The upper limit of physiological cardiac hyper-
trophy in highly trained elite athletes. 1991. N Engl J Med
1991,324; 295-301.
21. Whyte GP, George K, Sharma S, Firoozi S, Stephens N,
Senior R, et al. The upper limit of physiological cardiac
hypertrophy in elite male and female athletes: the British
experience. Eur J Appl Physiol, 2004; 92(4-5): 592-7.
22. Stout M. Athletes' heart and echocardiography: athletes'
heart. Echocardiography, 2008; 25(7): 749-54.
23. Venckunas T. Echocardiographic parameters in athletes of
different sports. Joumal of Sports Science and Medicine,
2008; 151-6.
24. Maron B.J., Pelliccia A, Spirito P. Cardiac disease in young
trained athletes. Insights into methods for distinguish-
ing athlete's heart from structural heart disease, with
particular emphasis on hypertrophic cardiomyopathy.
Circulation, 1995; 91(5): 1596-601.
25. Pelliccia A. Maron BJ, Di Paolo FM, Biffi A, Quattrini FM,
Pisicchio C, et al. Prevalence and clinical significance of
left atrial remodelling in competitive athletes. J Am Coll
Cardiol, 2005; 46(4): 690-6.
26. Ðasavarajaiah S, Sharma S, Firoozi S, Whyte G, Jackson
PG, McKenna WJ, et al. Physiological upper limits of left
atrial diameter in highly traincd adolescent athletes. J Am
Coll Cardiol, 2006; 47(11): 2341-2; author reply 2342.
27. Somauroo JD, Pyatt J, Jackson M, Perry R, D Ramsdale.
An echocardiographic assessment of cardiac morphology
and common ECG findings in tcenage professional soccer
players: reference ranges for use in screening. Heart, 2001;
85(6): 649-54.
28. Fagard RH. Athlete's heart: a meta-analysis of the echo-
cardiographic experience. Int J Sports Med, 1996; 17 Suppl
3: S140-4.
29. D'Ascenzi F, Cameli M, Zacá V, Lisi M, Santoro A,
Causarano A, Mondillo S. Supemormal Diastolic Function
and Role of Left Atrial Myocardial Deformation Analysis
by 2D Speckle Tracking Echocardiography in Elite Soccer
Players. Echocardiography, 2011; 28(3): 320-6.
30. Baggish AL, Hutter AM Jr, Wang F, Yared K, Weiner RB,
Kupperman E, et al., Cardiovascular screening in college
athletes with and without electrocardiography: A cross-
sectional study. Ann Intem Med, 2010; 152(5): 269-75.
ENGLISH SUMMARY
Prevalence of Abnormal Electrocardiographic Patterns in lcelandic
Soccer Players and Relationship with Echocardiographic Findings
Arnar Sigurðsson1, Halldóra Björnsdóttir23 Þórarinn Guðnason34, Axel F. Sigurðssonn2-3
An abnormal electrocardiogram (ECG) is common among young ath-
letes but the underlying cause is unclear. Therefore it is hard to predict
how accurate ECG is when screening for sudden cardiac death (SCD) in
elite athletes.
Objective: 1) to determine the prevalence of abnormal ECG patterns,
among soccer players, especially in relation to age and 2) to link ECG
patterns with echocardiographic findings in order to find out whether the
ECG can predict disease and/or physiological changes.
Materials and methods: A total of 159 male soccer players (16-45
years, mean age 25.5 years) that participated in the UEFA cup com-
petition 2008-2010 were studied. They underwent both an ECG and
echocardiography along with routine history and cardiologic examina-
tion, according to UEFA protocol. Results were classified and grouped
according to standards set by The European Society of Cardiology and
The American Society of Echocardiography.
Results: 84 (53%) had abnormal ECG patterns. The prevalence of
abnormal ECG patterns decreased with age. Echocardiographic findings
showed that left ventricular wall thickness, mass and diameter increased
with age, along with left atrial diameter. Left ventricular wall thickness,
diameter and mass were similar among those with an abnormal ECG
and those with a normal ECG.
Conclusion: The prevalence of abnormal ECG's is high in lcelandic
soccer players, a finding that usually does not indicate underlying heart
disease. There was no relationship between ECG changes and echo-
cardiographic findings. High prevalance of abnormal ECG patterns in
young athletes reduces the usefulness of ECG in screening for SCD.
Key words: sudden death in athletes, soccerplayers, electrocardiography, echocardiography, screening
Correspondence: Axel F. Sigurðsson, axel@hjartamidstodin.is
'Department of Life Sciences, University of lceland, 2Heart Center, 3Department of Cardiology, The National University Hospital of lceland, 4Læknasetrið
LÆKNAblaðið 2013/99 287