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Læknablaðið - 01.07.2024, Blaðsíða 15

Læknablaðið - 01.07.2024, Blaðsíða 15
L ÆKNABL AÐIÐ 2024/110 359 R A N N S Ó K N Heimildir 1. Krabbameinsfélagið. Krabbameinsskrá - Yfirlitstölfræði. Krabbameinsfélagið. 2023. https://www.krabb.is/rannsoknasetur/upplysingar-um-krabbamein/yfirlitstolfraedi/ - janúar 2024. 2. European Com. European Cancer Information System: 21% increase in new cancer cases by 2040 - European Commission. https://joint-research-centre.ec.europa.eu/ jrc-news-and-updates/european-cancer-information-system-21-increase-new-cancer- -cases-2040-2022-03-16_en - desember 2023. 3. Roser M, Ritchie H. Cancer. Our World Data. 2023. https://ourworldindata.org/cancer - nóvember 2023. 4. Zhao J, Xu L, Sun J, et al. Global trends in incidence, death, burden and risk factors of early-onset cancer from 1990 to 2019. BMJ Oncol. 2023;2(1). 5. Hagstofan: Mannfjöldaspá. Hagstofa Íslands. https://hagstofa.is/talnaefni/ibuar/mann- fjoldaspa/mannfjoldaspa - nóvember 2023. 6. World Health Organization. Cancer. 2022. https://www.who.int/news-room/fact- -sheets/detail/cancer - október 2023. 7. OECD/European Observatory on Health Systems and Policies. Iceland: Country Health Profile 2021, State of Health in the EU. OECD Publishing, Paris/European Observatory on Health Systems and Policies, Brussels.; 2021. 8. Herbst RS, Baas P, Kim DW, et al. Pembrolizumab versus docetaxel for previously treated, PD-L1-positive, advanced non-small-cell lung cancer (KEYNOTE-010): aA randomised controlled trial. Lancet Lond Engl. 2016;387(10027):1540-1550. 9. Topalian SL, Hodi FS, Brahmer JR, et al. Five-year survival and correlates among patients with advanced melanoma, renal cell carcinoma, or non–small cell lung cancer treated with Nivolumab. JAMA Oncol. 2019;5(10):1411-1420. 10. Curigliano G, Cardinale D, Suter T, et al. Cardiovascular toxicity induced by chemotherapy, targeted agents and radiotherapy: ESMO Clinical Practice Guidelines†. Ann Oncol. 2012;23:vii155-vii166. 11. Howard-Anderson J, Ganz PA, Bower JE, et al. Quality of life, fertility concerns, and behavioral health outcomes in younger breast cancer survivors: A systematic review. JNCI J Natl Cancer Inst. 2012;104(5):386-405. 12. IARC. Cancer Tomorrow. 2022. https://gco.iarc.fr/tomorrow/en - september 2023. 13. United Nations Department of Economic and Social Affairs. World Social Report 2023: Leaving No One Behind in an Ageing World. United Nations; 2023. 14. Hagstofa Íslands. Hagstofan: Frjósemi aldrei verið minni en árið 2022. Hagstofa Íslands. 2023. https://hagstofa.is/utgafur/frettasafn/mannfjoldi/faedingar-2022/ - des- ember 2023. 15. Krabbameinsfélagið. Töflur - Krabbameinsskrá. Krabbameinsfélagið. 2023. https:// www.krabb.is/rannsoknasetur/upplysingar-um-krabbamein/toflur/ - janúar 2024. 16. Engholm G, Ferlay J, Christensen N, et al. NORDCAN – a Nordic tool for cancer information, planning, quality control and research. Acta Oncol. 2010;49(5):725-736. 17. Larønningen S, Arvidsson G, Bray F, et al. NORDCAN: Cancer Incidence, Mortality, Prevalence and Survival in the Nordic Countries, Version 9.3 (15.09.2023). Association of the Nordic Cancer Registries. Cancer Registry of Norway. 2023. https://nordcan.iarc. fr/ - september 2023. 18. Larønningen S, Skog A, Engholm G, et al. Nordcan.R: a new tool for federated analysis and quality assurance of cancer registry data. Front Oncol. 2023;13. https://www. frontiersin.org/articles/10.3389/fonc.2023.1098342 - nóvember 2023. 19. Statistics Iceland. Methodology of population projections based on hierarchical Bayesian models. Stat Icel. 2023;108(4). 20. Nordic Statistics. POPU06: Population projections by reporting country, age, sex and time. Populations projections. 2024. https://pxweb.nordicstatistics.org:443/pxweb/en/ Nordic Statistics/Nordic Statistics__Demography__Population projections/POPU06.px/ - janúar 2024. 21. Møller B, Fekjaer H, Hakulinen T, et al. Prediction of cancer incidence in the Nordic countries: empirical comparison of different approaches. Stat Med. 2003;22(17):2751- 2766. 22. Hagstofa Íslands. Mannfjöldaspá 2018-2067. Hagtíðindi. 2018;103(24). 23. Nordic Co-operation. All-time low Nordic fertility rates. Nordic Statistics database. 2023. https://www.nordicstatistics.org/news/all-time-low-nordic-fertility-rates/ - des- ember 2023. 24. Nordic Co-operation. Nordic Statistics database. Nordic Statistics database. Published July 31, 2023. https://www.nordicstatistics.org/ - október 2023. 25. Hagstofa Íslands. Hagstofan: Innflytjendur 15,2% íbúa landsins. Hagstofa Íslands. 2023. https://hagstofa.is/utgafur/frettasafn/mannfjoldi/mannfjoldi-eftir-bakgrunni-2020/ - desember 2023. 26. Sigurdardottir LG, Jonasson JG, Stefansdottir S, et al. Data quality at the Icelandic Cancer Registry: Comparability, validity, timeliness and completeness. Acta Oncol. 2012;51(7):880-889. 27. Krabbameinsfélagið. Um Rannsóknasetrið. Krabbameinsfélagið. 2023. https://www. krabb.is/rannsoknasetur/starfsemi/um-rannsokna-og-skraningasetrid/ - janúar 2024 28. Hagstofa Íslands. Lýsigögn. Hagstofa. 2010. http://hagstofa.is/utgafur/lysigogn/ lysigogn/ - desember 2023. 29. Kim DD, Daly AT, Koethe BC, et al. Low-Value Prostate-Specific Antigen Test for Prostate Cancer Screening and Subsequent Health Care Utilization and Spending. JAMA Netw Open. 2022;5(11):e2243449. 30. Norðurlandaráð og Norræna ráðherranefndin. Norrænt samstarf. https://www.norden. org/is - nóvember 2023. INTRODUCTION: A large increase in new cancer cases is predicted worldwide, due to population growth, ageing and increased cancer risk. The age distribution of the Icelandic population is different from the other Nordic countries. The purpose of this study was to predict the number of new cancer cases in Iceland and other Nordic countries, and cancer survivors in Iceland, up to the year 2040. MATERIALS AND METHODS: Information on cancer diagnoses was retrieved from The Icelandic Cancer Registry and information on population projections from Statistics Iceland. Well known methods for population projection were used to predict the number of new cancer cases in 2040, but adjusted to consider Icelandic circumstances. It is also based on more recent data than is accessible elsewhere. Three different methods were used to estimate the number of survivors in 2040 and are presented here for the first time. RESULTS: In 2040 the predicted yearly average number of new cancer cases in Iceland will be up to 2,903 [95% CI 2.841-2.956], a 57% increase compared with 2022. The increase is higher in Iceland than in other Nordic countries (Norway 41%, Sweden 24%, Denmark 23%, Finland 21%). In 2022, the number of cancer survivors was around 17,500 and is predicted to be between 24,500 and 31,000 in 2040. CONCLUSION: The main reason for the predicted increase of cancer cases and survivors is population trends, especially the ageing of the population. This expected increase in the number of cancer patients and improved survival will increase the demand for healthcare. doi 10.17992/lbl.2024.0708.800 Eva Maria Guðmundsdóttir1 Elinborg Olafsdottir1 Nanna Margret Kristinsdottir1 Alfheiður Haraldsdottir1 Kristjana Sigurdardottir1 Laufey Tryggvadottir1,3 Helgi Birgisson1,4 Sigridur Gunnarsdottir1,2,3 1Icelandic Cancer Registry, Icelandic Cancer Society, 2Landspitali - The National University Hospital of Iceland, 3University of Iceland 4Department of Surgical Sciences, Uppsala University Hospital Correspondence: Sigridur Gunnarsdottir, sigridurg@krabb.is Key words: cancer, population, prediction, incidence, prevalence, survivors. Prediction of cancer incidence and prevalence in Iceland up to the year 2040 – Icelandic Cancer Registry and Research Center

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