Læknablaðið - 15.07.2010, Blaðsíða 20

FRÆÐIGREINAR
RANNSÓKNIR
Heimildir
1. Fraser WD. Hyperparathyroidism. Lancet 2009; 374:145-58.
2. Tfelt-Hansen J, Brown EM. The calcium-sensing receptor in
normal physiology and pathophysiology: a review. Crit Rev
Clin Lab Sci 2005; 42: 35-70.
3. Chan AK, Duh QY, Katz MH, Siperstein AE, Clark OH.
Clinical manifestations of primary hyperparathyroidism
before and after parathyroidectomy. A case-control study.
Ann Surg 1995; 222: 402-12.
4. Silverberg SJ, Bilezikian JR Evaluation and management
of primary hyperparathyroidism. J Clin Endocrinol Metab
1996; 81:2036-40.
5. Eigelberger MS, Cheah WK( Ituarte PH, Streja L, Duh QY,
Clark OH. The NIH criteria for parathyroidectomy in
asymptomatic primary hyperparathyroidism: are they too
limited? Ann Surg 2004;239: 528-35.
6. Mazzaglia PJ, Berber E, Kovach A, Milas M, Esselstyn
C, Siperstein AE. The changing presentation of
hyperparathyroidism over 3 decades. Arch Surg 2008; 143:
260-6.
7. Lundgren E, Ljunghall S, Akerstrom G, Hetta J, Mallmin
H, Rastad J. Case-control study on symptoms and signs of
„asymptomatic" primary hyperparathyroidism. Surgery
1998; 124: 980-5.
8. Mallette LE, Bilezikian JP, Heath DA, Aurbach GD. Primary
hyperparathyroidism: clinical and biochemical features.
Medicine (Baltimore) 1974; 53:127-46.
9. McAllion SJ, Paterson CR. Psychiatric morbidity in primary
hyperparathyroidism. Postgrad Med J 1989; 65: 628-31.
10. Coker LH, Rorie K, Cantley L, et al. Primary
hyperparathyroidism, cognition, and health-related quality
of life. Ann Surg 2005; 242: 642-50.
11. Wermers RA, Khosla S, Atkinson EJ, et al. Survival after
the diagnosis of hyperparathyroidism: a population-based
study. Am J Med 1998; 104:115-22.
12. Almqvist EG, Bondeson AG, Bondeson L, Nissborg A,
Smedgard P, Svensson SE. Cardiac dysfunction in mild
primary hyperparathyroidism assessed by radionuclide
angiography and echocardiography before and after
parathyroidectomy. Surgery 2002; 132:1126-32.
13. Sitges-Serra A, Bergenfelz A. Clinical update: sporadic
primary hyperparathyroidism. Lancet 2007; 370:468-70.
14. Wermers RA, Khosla S, Atkinson EJ, et al. Incidence of
primary hyperparathyroidism in Rochester, Minnesota,
1993-2001: an update on the changing epidemiology of the
disease. J Bone Miner Res 2006; 21:171-7.
15. Salti GI, Fedorak I, Yashiro T, et al. Continuing evolution in
the operative management of primary hyperparathyroidism.
Arch Surg 1992; 127: 831-6.
16. Szabo E, Lundgren E, Juhlin C, Ljunghall S, Akerstrom
G, Rastad J. Double parathyroid adenoma, a clinically
nondistinct entity of primary hyperparathyroidism. World J
Surg 1998; 22:708-13.
17. Ruda JM, Hollenbeak CS, Stack BC, Jr. A systematic review of
the diagnosis and treatment of primary hyperparathyroidism
from 1995 to 2003. Otolaryngol Head Neck Surg 2005; 132:
359-72.
18. Phitayakom R, McHenry CR. Incidence and location of
ectopic abnormal parathyroid glands. Am J Surg 2006; 191:
418-23.
19. Thompson NW, Eckhauser FE, Hamess JK. The anatomy of
primary hyperparathyroidism. Surgery 1982; 92: 814-21.
20 Lew JI, Solorzano CC. Surgical management of primary
hyperparathyroidism: state of the art. Surg Clin North Am
2009; 89:1205-25.
21. Udelsman R, Pasieka JL, Sturgeon C, Young JE, Clark OH.
Surgery for asymptomatic primary hyperparathyroidism:
proceedings of the third intemational workshop. J Clin
Endocrinol Metab 2009; 94: 366-72.
22. Civelek AC, Ozalp E, Donovan P, Udelsman R. Prospective
evaluation of delayed technetium-99m sestamibi SPECT
scintigraphy for preoperative localization of primary
hyperparathyroidism. Surgery 2002; 131:149-57.
23. Udelsman R. Six hundred fifty-six consecutive explorations
for primary hyperparathyroidism. Ann Surg 2002; 235: 665-
70
24. Caron NR, Pasieka JL. What symptom improvement can be
expected after operation for primary hyperparathyroidism?
World J Surg 2009; 33: 2244-55.
25. Grant CS, Thompson G, Farley D, van Heerden J.
Primary hyperparathyroidism surgical management since
the introduction of minimally invasive parathyroidectomy:
Mayo Clinic experience. Arch Surg 2005; 140: 472-8.
26. Allendorf J, DiGorgi M, Spanknebel K, Inabnet W, Chabot
J, Logerfo P. 1112 consecutive bilateral neck explorations for
primary hyperparathyroidism. World J Surg 2007; 31: 2075-
80.
27. Lunca S, Stanescu C, Bouras G, Vix M, Marescaux J.
A difficult case of mediastinal parathyroid adenoma:
theoretical and clinical considerations. Chirurgia (Bucur)
2004; 99: 563-6.
28. Callender GG, Grubbs, Vu T, Hofstetter WL, et al. The fallen
one: the inferior parathyroid gland that descends into the
mediastinum. J Am Coll Surg 2009; 208: 887-95.
>-
CC
<
s
2
D
U)
I
<n
_i
o
z
LIJ
Primary hyperparathyroidism due to an intrathoracic parathyroid adenoma.
- A case report and review of the literature
A 72 year old gentleman presented to the emergency
department with symptoms of diffuse joint and muscular
pain, fatigue and diminished memory. Serum calcium
and parathyroid hormone levels were raised, consistent
with primary hyperparathyroidism. No abnormality was
found on an ultrasound scan of the neck. However, a
sestamibi scan suggested a possible adenoma in the
anterior mediastinum, which on computed tomography
(CT) scan was 1.5 cm in size. A partial upper sternotomy
was performed in order to excise the adenoma and
his symptoms disappeared within several weeks. This
case highlights the variable and commonly nonspecific
symptoms of primary hyperparathyroidism and the
less well known fact that parathyroid adenoma may
occasionally be found intrathoracically.
Thorhallsdottir H, Asgeirsson KS, Gudbjartsson T.
Primary hyperparathyroidism due to an intrathoracic parathyroid adenoma. - A case
report and review of the literature. Icel Med J 2010; 96: 469-72.
Key words: Primary hyperparathyroidism, hypercatcemia, parathyroid adenoma,
mediastinum, surgery, case report.
Correspondence: Tómas Guðbjartsson, tomasgud@landspitali.is
Barst: 30. nóvember 2009, - samþykkt til birtingar: 1. maí 2010
Hagsmunatengsl: Engin
472 LÆKNAblaðið 2010/96