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Læknablaðið - 15.11.2011, Blaðsíða 15

Læknablaðið - 15.11.2011, Blaðsíða 15
RANNSÓKN Heimildir 1. Amórsson T, Torfason B, Ólafsson G, Alfreðsson H, Jóhannsson KB, Guðbjartsson T. Hjartaskurðlækningar á íslandi í 20 ár. Ágrip erinda af vísindaþingi Skurð- læknafélags íslands og Svæfinga- og gjörgæslulæknafélags íslands. E 24. Læknablaðið 2007; 93: 320. 2. Rajamannan NM, Bonow RO, Rahimtoola SH. Calcific aortic stenosis: an update. Nat Clin Pract Cardiovasc Med 2007; 4: 254-62. 3. Pai RG, Kapoor N, Bansal RC, Varadarajan P. Malignant natural history of asymptomatic severe aortic stenosis: benefit of aortic valve replacement. Ann Thorac Surg 2006; 82: 2116-22. 4. Krane M, Voss B, Hiebinger A, et al. Twenty years of cardiac surgery in patients aged 80 years and older: risks and benefits. Ann Thorac Surg 2011; 91: 506-13. 5. Khan SS, Trento A, DeRobertis M, et al. Twenty-year comparison of tissue and mechanical valve replacement. J Thorac Cardiovasc Surg 2001; 122: 257-69. 6. Toole JM, Stroud MR, Kratz JM, et al. Twenty-five year experience with the St. Jude medical mechanical valve prosthesis. Ann Thorac Surg 2010; 89:1402-9. 7. Emery RW, Krogh CC, Arom KV, et al. The St. Jude Medical cardiac valve prosthesis: a 25-year experience with single valve replacement. Ann Thorac Surg 2005; 79: 776-82; discussion 82-3. 8. Ingvarsdóttir IL, Viktorsson SA, Helgadóttir S, et al. Lokuskipti vegna ósæðarlokuþrengsla á íslandi 2002-2006: Ábendingar og snemmkomnir fylgikvillar. Læknablaðið 2011; 97: 523-7. 9. Akins CW, Miller DC, Turina MI, et al. Guidelines for reporting mortality and morbidity after cardiac valve interventions. J Thorac Cardiovasc Surg 2008; 135: 732-8. 10. Doty JR, Flores JH, Millar RC, Doty DB. Aortic valve replacement with medtronic freestyle bioprosthesis: operative technique and results. J Card Surg 1998; 13: 208- 17. 11. Eichinger WB, Hettich IM, Ruzicka DJ, et al. Twenty-year experience with the St. Jude medical Biocor bioprosthesis in the aortic position. Ann Thorac Surg 2008; 86:1204-10. 12. David TE, Ivanov J, Armstrong S, Feindel CM, Cohen G. Late results of heart valve replacement with the Hancock II bioprosthesis. J Thorac Cardiovasc Surg 2001; 121: 268-77. 13. Vrandecic M, Fantini FA, Filho BG, de O, da C, Vrandecic E. Long-term results with the Biocor-SJM stentless porcine aortic bioprosthesis. J Heart Valve Dis 2002; 11:47-53. 14. Polvani G, Barili F, Dainese L, et al. Long-term results after aortic valve replacement with the Bravo 400 stentless xenograft. Ann Thorac Surg 2005; 80:495-501. 15. Ali A, Lim E, Halstead J, et al. Porcine or human stentless valves for aortic valve replacement? Results of a 10-year comparative study. J Heart Valve Dis 2003; 12: 430-5; discussion 435. 16. Auriemma S, D'Onofrio A, Brunelli M, et al. Long-term results of aortic valve replacement with Edwards Prima Plus stentless bioprosthesis: eleven years' follow up. J Heart Valve Dis 2006; 15:6 91-5; discussion 695. 17. Bonow RO, Carabello BA, Chatterjee K, et al. 2008 focused update incorporated into the ACC/AHA 2006 guidelines for the management of patients with valvular heart disease: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to revise the 1998 guidelines for the management of patients with valvular heart disease). Endorsed by the Society of Cardiovascular Anesthesiologists, Society for Cardiovascular Angio- graphy and Interventions, and Society of Thoracic Surge- ons. J Am Coll Cardiol 2008; 52: el-142. 18. Cannegieter SC, Rosendaal FR, Briet E. Thromboembolic and bleeding complications in patients with mechanical heart valve prostheses. Circulation 1994; 89: 635-41. 19. Horstkotte D, Schulte H, Bircks W, Strauer B. Unexpected findings conceming thromboembolic complications and anticoagulation after complete 10 year follow up of patients with St. Jude Medical prostheses. J Heart Valve Dis 1993; 2: 291-301. 20. Koertke H, Minami K, Boethig D, et al. INR self- management permits lower anticoagulation levels after mechanical heart valve replacement. Circulation 2003; 108 Suppl 1: II75-8. 21. Sjogren J, Gudbjartsson T, Thulin LI. Long-term outcome of the MitroFlow pericardial bioprosthesis in the elderly after aortic valve replacement. J Heart Valve Dis 2006; 15: 197-202. 22. Butchart EG, Li HH, Payne N, Buchan K, Grunkemeier GL. Twenty years' experience with the Medtronic Hall valve. J Thorac Cardiovasc Surg 2001; 121:1090-100. 23. Bach DS, Kon ND, Dumesnil JG, Sintek CF, Doty DB. Ten-year outcome after aortic valve replacement with the freestyle stentless bioprosthesis. Ann Thorac Surg 2005; 80: 480-6; discussion 486-7. ENGLISH SUMMARY Aortic valve replacement for aortic stenosis in lceland 2002-2006: Long term complications and survival Viktorsson SA , Ingvarsdottir IL, Hreinsson K, Sigurdsson Ml, Helgadottir S, Arnorsson Th, Danielsen R, Gudbjartsson T Objective: To investigate long-term complications and survival following aortic valve replacement (AVR) in patients with aortic stenosis (AS) in lceiand. Material and methods: Included were 156 patients (average age 71.7 yrs, 64.7% males) that underwent AVR for AS at Landspitali between 2002 and 2006. A mechanical prosthesis was used in 29 patients (18.6%) and a bioprosthesis in 127. Long-term complications and operation-related admissions were registered from hospital and outpatient records until April 1,2010. Overall survival was estimated and compared with the icelandic population of the same age and gender. Results: The mean preop. EuroSCORE(st) was 6.9%, the max. transvalvular pressure gradient 74.1 mmHg and the left ventricular ejection fraction (LVEF) (57.2%). At six months following AVR the maximal pressure gradient was 19.8 mmHg (range; 2.5-38). Echocardiography results were not available for 23.6% of the patients 6 months postoperatively. In the follow-up period one in four patients was admitted due to valve-related problems. Re-admission rate was 6.0/100 patient-years (pt-y); most commonly due to cardiac failure (1.7/100 pt-y), emboli (1.6/100 pt-y), hemorrhage (1.6/100 pt-y), endocarditis (0.7/100 pt-y) and myocardial infarction (0.4/100 pt-y). Survival at 1 and 5 year was 89.7% and 78.2%, respectively, making survival comparable to the estimated survival of lcelanders of the same age and gender. Conclusions: The rate of long-term complications following AVR in lceland is in line with other studies. The same applies to long-term survival, which was similar to that of the lcelandic population of the same age and gender. Key words: Aortic valve replacement, aortic stenosis, heart surgery, results, iong-term complication, survival. Correspondence: Tómas Guðbjartsson, tomasgud<dlandspitali.is LÆKNAblaðið 2011/97 595
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