Læknablaðið

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Læknablaðið - 15.11.2011, Page 30

Læknablaðið - 15.11.2011, Page 30
RANNSÓKN Heimildir 1. Shi S, Morike K, Klotz U. The clinical implications of ageing for rational drug therapy. Eur J Clin Pharmacol 2008; 64:183-99. 2. Fialova D, Onder G. Medication errors in elderly people: contributing factors and future perspectives. Brit J Clin Pharmacol 2009; 67: 641-5. 3. United Nations. World Population Ageing 2009. United Nations, New York 2009. 4. Brekke M, Rognstad S, Straand J, et al. Pharmacologically inappropriate prescriptions for elderly patients in general practice: How common? Baseline data from The Prescription Peer Academic Detailing (Rx-PAD) study. Scand J Prim Health Care 2008; 26:80-5. 5. Crome P. What's different about older people. Toxicology 2003; 192:49-54. 6. Straand J, Fetveit A, Rognstad S, Gjelstad S, Brekke M, Dalen I. A cluster-randomized educational intervention to reduce inappropriate prescription pattems for elderly patients in general practice - The Prescription Peer Academic Detailing (Rx-PAD) study [NCT00281450]. BMC Health Serv Res 2006; 6: 72. 7. Heimisdóttir M. Mælingar á gæðum. Læknablaðið 2005; 91:44. 8. Fick DM, Cooper JW, Wade WE, Waller JL, Maclean JR, Beers MH. Updating the beers criteria for potentially inappropriate medication use in older adults - Results of a US consensus panel of experts. Arch Int Med 2003; 163: 2716-24. 9. Gallagher P, Ryan C, Byme S, Kennedy J, O'Mahony D. STOPP (Screening Tool of Older Person's Prescriptions) and START (Screening Tool to Alert Doctors to Right Treatment). Consensus validation. Int J Clin Pharmacol Ther 2008; 46:72-83. 10. Spinewine A, Schmader KE, Barber N, et al. Prescribing in elderly people 1 - Appropriate prescribing in elderly people: how well can it be measured and optimised? Lancet 2007; 370:173-84. 11. Page RL, Linnebur SA, Bryant LL, Ruscin JM. Inappropriate prescribing in the hospitalized elderly patient: Defining the problem, evaluation tools, and possible solutions. Clin Interv Aging 2010; 5: 75-87. 12. Roth MT, Weinberger M, Campbell WH. Measuring the Quality of Medication Use in Older Adults. J Am Geriatr Soc 2009; 57:1096-102. 13. Levy HB, Marcus EL, Christen C. Beyond the beers criteria: a comparative Overview of Explicit Criteria. Ann Pharmacother 2010; 44:1968-75. 14. Beers MH, Ouslander JG, Rollingher I, Reuben DB, Brooks J, Beck JC. Explicit criteria for for determining inappropriate medication use in nursing-home residents. Arch Intern Med 1991; 151:1825-32. 15. Straand J, Rokstad KS. Elderly patients in general practice: diagnoses, drugs and inappropriate prescriptions. A report from the More & Romsdal Prescription Study. Fam Pract 1999; 16: 380-8. 16. Aparasu RR, Mort JR. Inappropriate prescribing for the elderly: Beers criteria-based review. Ann Pharmacother 2000; 34: 338-46. 17. Gurwitz JH. The age/gender interface in geriatric pharmacotherapy. J Womens Health 2005; 14: 68-72. 18. Johnell K, Fastbom J, Rosen M, Leimanis A. Inappropriate drug use in the elderly: a nationwide register-based study. Ann Pharmacother 2007; 41:1243-8. 19. Johnell K, Weitoft GR, Fastbom J. Sex Differences in Inappropriate Drug Use: a Register-Based Study of Over 600,000 Older People. Ann Pharmacother 2009; 43:1233-8. 20. Helgason T, Tómasson K, Zoéga T. Algengi og dreifing notkunar geðdeyfðar-, kvíða- og svefnlyfja. Læknablaðið 2003; 89:15-22. 21. Bertakis KD. The influence of gender on the doctor-patient interaction. Patient Educ Counsel 2009; 76: 356-60. 22. Þengilsdóttir G. Lyf sem orsök innlagna - vísbendingar í sjúkraskrám [meistaraprófsritgerð]. Lyfjafræðideild Háskóla íslands, 2009. 23. Samúelsson S, Bjömsson S, Jóhannesson BH, Jónsson PV. Lyfjanotkun aldraðra á bráðasjúkrahúsi - Aukaverkanir og gæðavísar. Læknablaðið 2000; 86:11-6. 24. Samúelsson S, Zoéga H, Guðmundsson A, Halldórsson M. Algengi geðlyfjanotkunar eldri íslendinga utan stofnana. Læknablaðið 2009; 95:11-7. 25. Ryan C, O'Mahony D, Byme S. Application of STOPP and START Criteria: Interrater Reliability Among Pharmacists. Ann Pharmacother 2009; 43:1239-44. 26. Banning M. A review of interventions used to improve adherence to medication in older people. Int J Nurs Studies 2009; 46:1505-15. 27. Rochon PA, Gurwitz JH. Prescribing for seniors - Neither too much nor too little. JAMA 1999; 282:113-5. ENGLISH SUMMARY Quality indicators of drug therapy at hospital admission among elderly patients Sigurðardóttir MS, Guðmundsson A, Guðmundsdóttir ÞK, Almarsdóttir AB Objective: Increased morbidity and higher prevalence of medication use commonly coexists among the elderly. When managed appropriately, older patients can benefit from drug therapy. However, drug related problems are more frequent and more serious in the elderly. The aim of the study was to assess the quality of medication use in older people at hospital admission. Material and methods: A retrospective medical record review was performed for patients 70 years and older who had an unplanned admission to the internal medicine and geriatric units at Landspitali University Hospital in 2007. Among the sampled medical records, 913 met inclusion criteria. Assessment was carried out using 15 drug-specific quality indicators. Results: Mean age was 80.9 years and 54.5% were women. Mean number of drugs at admission was 7.0 for women and 6.5 for men (p=0.047). The prevalence of having one or more quality indicators on admission was 48.4%. Women were more likely to have a quality indicator than men (women 56.2%, men 39.9%). The probability also increased with increasing age and number of drugs. Conclusions: The quality of drug therapy among older patients at hospital admission appears to be suboptimal. A more accurate estimate of the problem could be obtained through a prospective study where drug regimens are correlated with symptoms and reason for admission. Additional studies are also needed in the outpatient setting. Such studies could provide more accurate evidence and assist policy making towards improved quality of drug prescribing for a growing number of older patients. Keywords: elderly, quality indicators, hospitalization, drugs, inappropriate prescribing. Correspondence: Anna Birna Almarsdóttir, annaba@hi.is 610 LÆKNAblaðið 2011/97

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