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Læknablaðið - 15.11.2011, Page 38

Læknablaðið - 15.11.2011, Page 38
Y F I R L I T grein nema meðferðaraðilar mæti slíkum skilmerkjum. í annan stað eru rannsóknir á samþættri meðferð komnar skammt á veg. í þriðja lagi eru árangursrannsóknir gjarnan gerðar á fremur einsleitum hópi sjúklinga sem endurspeglar ekki alltaf nægilega klínískan raunveruleika þar sem vímugjafar, erfiðar félagslegar aðstæður og persónuleikaröskun getur flækt myndina. Að lokum er vert að nefna að í sumum samanburðarrannsóknum á HAM og lyfjameðferð hefur verið notast við þríhringa þunglyndislyf sem eru ekki lengur fyrsta lyfjameðferð við kvíða og þunglyndi vegna aukaverkana og hættu á hjartsláttartruflunum, séu þau tekin í of stórum skömmtum. Af yfirlitinu má álykta að HAM sé gagnleg meðferð við lyndis- og kvíðaröskunum. Aukaverkanir eru nær aldrei vandamál og langtímaárangur að meðferð lokinni oft góður. í þessari grein leyfir rýmið ekki að fjallað sé um árangur HAM við ýmsum öðrum vandamálum sem sálfræðingar, geðlæknar, heimilislæknar, lyflæknar og aðrir heilbrigðisstarfsmenn glíma við í starfi sínu. Dæmi um slíkt eru persónuleikaraskanir, geðklofi, geðhvarfasýki, fíknivandamál og átraskanir. Slík umfjöllun er efni í aðra grein. ENGLISH SUMMARY Efficacy of cognitive behavioral therapy in the treatment of mood and anxiety disorders in adults Sighvatsson MB, Kristjánsdóttir H. Sigurðsson E, Sigurðsson JF Cognitive behavioral therapy (CBT) represents that form of psychotherapy which has most research data to build on in the treatment of mood and anxiety disorders for adults. In this review we will introduce CBT and present the results of pertinent outcome research. Efficacy at the end of treatment is discussed, as well as long term effectiveness and the efficacy of combined treatment with medication and CBT. In addition, we discuss the pros and cons of group CBT compared to CBT in individual format, and comorbidity of mental disorders. According to this review CBT is efficacious for major depressive disorder, generalized anxiety disorder, panic disorder, post-traumatic stress disorder, obsessive compulsive disorder, social phobia and specific phobia. Efficacy of CBT is equal to or better than efficacy of drugs in the treatment of the above disorders, but there is less access to CBT. Longterm effectiveness of CBT appears to be good, but research on combined treatment is yet in its infancy and conclusions are premature on its place in treatment. Key words: Cognitive behavioral therapy, psychotropic treatment, efíicacy, long-term efíects, combined treatment, mental disorders, adults. Correspondence: Hafrún Kristjánsdóttir, hafrunkr@landspitali.is Heimildir 1. Prochaska JM, Norcross JC. Systems of Psychotherapy: A Transtheoretical Analysis. 7th ed. Brooks/Cole, Pacific Grove Califomia 2010. 2. Beck AT. How an anomalous finding led to a new system of psychotherapy. Nat Med 2006; 12:1139-41. 3. Butler AC, Chapman JE, Forman EM, Beck AT. The empirical status of cognitive-behavioral therapy: a review of meta-analyses. Clin Psychol Rev 2006; 26:17-31. 4. Beck AT. The current state of cognitive therapy: a 40-year retrospective. Arch Gen Psychiatry 2005; 62: 953-9. 5. Beck AT. Cognitive Therapy and the Emotional Disorders. Penguin Books, New York 1976. 6. Bennett-Levy J, Butler G, Fennell M, Hackmann A, Mueller, M, Westbrook D. Oxford Guide to Behavioral Experiments in Cognitive Therapy. Oxford University Press, Oxford 2004. 7. Tolin DF. Is cognitive-behavioral therapy more effective than other therapies? A meta-analytic review. Clin Psychol Rev 2010; 30: 710-20. 8. 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Anxiety: Management of anxiety (panic disorder, with or without agoraphobia, and generalised anxiety disorder) in adults in primary, secondary and community care. Clinical guideline 22. NICE, London 2004. 30. Wright J. Integrating cognitive behavioral therapy and pharmacotherapy. In: Leahy RL, ed. Contemporary Cognitive Therapy. Guilford, New York 2004:341-67. 31. Agnarsdóttir A, Eyþórsdóttir Á, Einarsson E, et al. Þunglyndi og kvíði - klínískar leiðbeiningar. Land- spítalinn 2011 www.Iandspitali.is - september 2011 32. Sánchez-Meca J, Rosa-AIcázar AI, Marín-Martínez F, Gómez-Conesa A. Psychological treatment of panic disorder with or without agoraphobia: A meta analysis. Clin Psychol Rev 2010; 30: 37-50. 33. Barlow DH, Gorman JM, Shear MK, Woods SW. Cognitive- behavioral therapy, imipramine, or their combination for panic disorder: A randomized controlled trial. JAMA 2000; 283: 2529-36. 34. van Apeldoom, FJ, Timmerman ME, Merch PPA, et al. A randomized trial of cognitive-behavioral therapy or selective serotonin reuptake inhibitor or both combined for panic disorder with or without agoraphobia: treatment results through 1-year follow-up. J Clin Psychiatry 2010; 71:574-86. 618 LÆKNAblaðið 2011/97 i

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