Læknablaðið - 15.12.2013, Blaðsíða 22
RANNSÓKN
ENGLISH SUMMARY
Incidence and management of ectopic pregnancy in lceland 2000-2009
Baldvinsdottir A', Gudmundsson JA' 2, Geirsson RT'-2
Introduction: Ectopic pregnancy can be life-threatening. Its treatment
has changed radically during the last two decades. The study objective
was to evaluate incidence and treatment of ectopic pregnancy in the
lcelandic population during the decade 2000-2009.
Material and methods: Information was collected about all diagnosed
cases, place and method of treatment and admissions. The annual
incidence was calculated with reference to number of pregnancies
(n/1000), number of women aged 15-44 years (n/10 000) and by 5-year
age groups, comparing the periods 2000-2004 and 2005-2009.
Results: The number of ectopic pregnancies during these 10 years was
836, or 444 during the years 2000-2004 and 392 during 2005-2009. The
average annual incidence was 15.6/1000 pregnancies and 12.9/10 000
women. There was an annual incidence reduction from 17.3 to 14.1/1000
Key words: Ectopic pregnancy, incidence, surgical procedures, extrauterine, methotrexate.
Correspondence: Jens A. Guömundsson, jens@landspitali.is
'University o f lceland,1Landspitali University Hospital.
pregnancies (p<0.01) and 14.1 to 11.7/10 000 women (p<0.01). Surgery
was the primary treatment for 94.9% of women, methotrexate in 3.2%
and expectant management in 1.9%. Surgical management decreased
from 98.0% to 91.3% between 5-year periods as medical treatment
increased (0.4% to 6.4%; p<0.0001). The proportion of laparoscopic
procedures increased from 80.5% to 91.1% (p<0.0001). In the university
referral hospital this changed from 91.3% to 98.1% (p<0.001) and in rural
hospitals from 44.0% to 69.3% (p<0.001). Mean hospital stay after open
surgery was 3.2 days, but 0.9 days after laparoscopy.
Conclusions: The incidence reduction of ectopic pregnancy is comp-
arable to the development in neighbouring countries. Management
has changed with increased use of laparoscopic surgery, medical and
expectant treatment.
570 LÆKNAblaðið 2013/99