Læknablaðið - 15.10.1999, Blaðsíða 23

LÆKNABLAÐIÐ 1999; 85
787
Nýgengi krabbameina meðal
íslenskra iðnverkakvenna
Hólmfríður K. Gunnarsdóttir1, Vilhjálmur Rafnsson2
Cancer incidence among Icelandic female
industrial workers
Gunnarsdóttir HK, Rafnsson V
Læknablaðið 1999; 85: 787-96
Objective: The aim of the present study was to in-
vestigate whether the cancer incidence pattern
aniong unskilled female industrial workers in Iceland
reflects a social divergence.
Material and methods: The design was that of a
retrospective cohort study. The cohort comprised
13,934 women who contributed to a pension fund for
industrial workers in Reykjavík during the period
1970-1997. The follow-up time was 1975-1997. The
cancer cases were found by record linkage with the
Cancer Registry, and the rates compared to those of
the general female population with indirect standar-
disation. Standardised incidence ratios (SIRs) and
95% confidence intervals (95% CI) were calculated
with and without 10 years lag-time, both for the co-
hort as a whole and after the study group had been re-
stricted to those who had contributed to the pension
fund any time after reaching 20 years of age.
Kesults: Results showed an excess of lung cancer,
both when lag-time was applied and not applied, and
before and after restriction had been made. SIRs for
cervix cancer, and cancers of the colon, bladder,
brain, connective tissue, and for cancers of the hema-
topoietic system were moderately elevated. There
was an excess of cancer of corpus uteri, especially
when 10 years lag-time was applied, both in the
whole group (SIR 1.67), and in the restricted cohort
(SIR 1.69), and among those with a long employ-
Frá ’atvinnusjúkdómadeild Vinnueftirlits ríkisins, zRann-
sóknastofu í heilbrigðisfræði, Háskóla íslands. Fyrirspurnir,
bréfaskipti: Hólmfríður K. Gunnarsdóttir, atvinnusjúkdóma-
deild Vinnueftirlits ríkisins, Bíldshöfða 16, 112 Reykjavík.
Netfang: hkg@ver.is
Lykilorð: krabbamein, nýgengi, konur, iðnverkakonur,
þjóðfélagshópar.
ment-time (SIR 1.79). No deficit was seen for breast
cancer, whereas this was found for ovary cancer.
Conclusions: The cancer pattern was in accordance
with the results of other studies on women in this
social category and indicates excessive smoking in
the group. The excess of cancer of corpus uteri was
unexpected. Because the group is burdened with
various physical and chemical exposures at work,
possible hazardous effects of these cannot be exclu-
ded.
Key words: cancer, incidence, women, factory workers,
social category.
Ágrip
Tilgangur: Tilgangur rannsóknarinnar var
að kanna hvort félagslegur mismunur endur-
speglist í krabbameinsmynstrinu hjá íslenskum
iðnverkakonum.
Efniviður og aðferðir: Rannsóknarsniðið var
afturskyggn hóprannsókn. í rannsóknarhópn-
um voru 13.934 konur sem greiddu í lífeyris-
sjóð félags verksmiðjufólks í Reykjavík á ára-
bilinu 1970-1997. Fylgitíminn var 1975-1997.
Upplýsingar um krabbamein í hópnum fengust
nieð tölvutengingu á kennitölum við Krabba-
meinsskrá. Gerð var óbein stöðlun, reiknuð
stöðluð nýgengihlutföll (standardised incidence
ratios, SIRs) og 95% öryggisbil (confidence
intervals, CI), með og án 10 ára biðtíma (lag-
time), bæði fyrir hópinn í heild og eftir að rann-
sóknarhópurinn hafði verið takmarkaður við
konur sem áttu greiðslu í lífeyrissjóðnum eftir
að þær urðu tvítugar.
Niðurstöður: Lungnakrabbamein var tíðara
meðal iðnverkakvennanna en annarra, hvort
heldur litið var á hópinn í heild eða eftir tak-
mörkun og með og án biðtíma. Staðlað nýgengi-
hlutfall leghálskrabbameins og krabbameina í
ristli, þvagblöðru, heila, bandvef og í blóð-
frumnamyndandi keifi var nokkuð hækkað. Ný-