Læknablaðið - 15.12.1997, Page 23

LÆKNABLAÐIÐ 1997; 83
809
orðið aukning á nýgengi hjartagalla meðal ein-
bura með tilliti til tæknifrjóvgana.
Þegar þess er gætt hversu lítið er í raun vitað
um orsakir meðfæddra hjartagalla, sjúkdóm
sem hrjáir 1% allra barna og 3% tvíbura, hlýtur
að teljast þörf ítarlegri rannsókna.
Þakkir
Vísindasjóði Landspítalans eru færðar þakk-
ir fyrir fjárstuðning.
HEIMILDIR
1. Sigfússon G, Helgason H. Nýgengi og greining með-
fæddra hjartagalla á íslandi. Læknablaðið 1993; 3: 107-
14.
2. Mitchell SC, Korones SB, Berendes HW. Congenital
heart disease in 56,109 births. Circulation 1971; 43, 323-
32.
3. Meberg A, Otterstad JE, Froland G. Barn med medf0dt
hjertfeil i Vestfold 1982-88. Tidsskr Nor Lægeforen
1990; 110: 354-7.
4. Berg KA. Astemborski JA, Bougham JA, Ferencz C.
Congenital cardiovascular malformations in twins and
triplets from a population-based study. AJDC1989; 143:
1461-3.
5. Kallén B. Congenital malformations in twins: a pop-
ulation study. Acta Genet Med Gemellol 1986; 35: 167-
78.
6. Hay S, Wehrung DA. Congenital malformations in
twins. Am J Hum Genet 1970; 22: 662-78.
7. Myrianthopoulos NC. Congenital malformations in
twins: epidemiologic survey. Birth Defects (Original Ar-
ticle Series) 1975; 11: 1-39.
8. Windham GC, Bjerkedal T. Malformations in twins and
their siblings, Norway, 1967-79. Acta Genet Med Ge-
mellol 1984; 33: 87-95.
9. Ramos-Arroyo MA. Birth defects in twins: study in a
Spanish population. Acta Genet Med Gemellol 1991; 40:
337-44.
10. Pradat P. Epidemiology of major congenital heart de-
fects in Sweden, 1981-1986. J Epidemiol Comm Health
1992; 46: 211-5.
11. Nora JJ, Nora AH. The evolution ofspecificgenetic and
environmental counseling in congenital heart diseases.
Circulation 1978; 57: 205-13.
12. Landshagir, Hagskýrslur íslands III, 39. Reykjavík:
Hagstofa íslands, 1996: 59.
13. Listi yfir fjölbura fædda á íslandi 1986-1996. Reykjavík:
Hagstofa íslands, 1997.
14. Zetterquist P. A clinical and genetic study of congenital
heart defects [dissertation]. Uppsala: The Institute for
Medical Genetics, University of Uppsala, Sweden, 1972.
15. Schinzel AAGL, Smith DW, Miller JR. Monozygotic
twinning and structural defects. J Pediatrics 1979; 95:
921-30.
16. Myrianthopoulos NC. Congenital malformations: the
contribution of twin studies. Birth Defects (Original
Article Series) 1978; 14: 151-65.
17. Ágústsson Þ, Geirsson RT. Athugun á tvíburafæðingum
eftir eðlilegan getnað og glasafrjóvgun. Læknablaðið
1995; 81: 242-7.
18. Fyler DC. Report of the New England regional infant
cardiac program. Pediatrics 1980; 65/Suppl.: 375-410.
19. Emmanouilides GC, Riemenschneider TA, Allen HD,
Gutgesell HP (ed.). Moss and Adams Heart Disease in
Infants, Children and Adolescents. 5th ed. Baltimore,
USA: Williams and Wilkins, 1995.
20. Martin GR, Perry LW, Ferencz C. Increased prevalence
of ventricular septal defect: epidemic or improved diag-
nosis. Pediatrics 1989; 83: 200-3.
21. Moore KL. The Developing Human. 4th ed. Philadel-
phia, USA: W.B. Saunders, 1988: 122.