Læknablaðið : fylgirit - 01.08.1978, Qupperneq 66

Læknablaðið : fylgirit - 01.08.1978, Qupperneq 66
64 lega skýrð. Alfai-fetoprotein kemur fram í serum, þegar endurnýjun er á lifrarvef eftir áverka (6). Endurkoma alfai-feto- proteins hjá okkar sjúklingi táknar því ekki nauðsynlega æxlisvöxt, þar sem cir- rhosis er einungis á byrjunarstigi og má því búast við endurnýjun á lifrarvef. Horfur eru yfirleitt slæmar hjá sjúk- lingum með hepatoma. Á þetta einkum við ef cirrhosis er einnig til staðar og má þá gera ráð fyrir að nær helmingur slíkra sjúklinga deyi úr lifrar-uppgjöf á næstu mánuðum eftir aðgerð. Hér að framan hefur verið farið yfir nokkur tæknileg atriði í sambandi við lifrarresection, sem geta komið að notum, bæði við electivar aðgerðir vegna æxla, svo og við bráðaaðgerðir vegna meiri hátt- ar áverka á lifur. Einnig er farið yfir nokkur helstu atriði í hjúkrun þessara sjúklinga eftir aðgerð. SUMMARY. A seventy one year old man was diagnosed as having carcinoma of the liver. This diagnosis was made on the basis of an arteriogram and supported by the presence of alphai-fetoprotein in serum. A percutaneous needle-biopsy showed hemosiderosis. The patient underwent a right hepatic lobectomy following a frozen section diagnosis of hepatic carcinoma. The postopera- tive course was uneventful and the patient is now doing well five months after surgery. Alphai-fetoprotein was not found on the 12th postoperative day but is now again present. The possibility that this might be because of a regenerative process in the liver or tumor is discussed. The general post-operative care is briefly discussed. HEIMILDIR: 1. Adson M.A.: Major hepatic resections: Elec- tive operations. Mayo Clinic proceedings 42: 791-801 (Dec. 1967). 2. Almersjö, O., et. al.: Enzyme and function changes after extensive liverresection in man. Annals of Surgery 111-118. January 1969. 3. Caty Blake: Essential Steps in Hepatic Re- sections. Surgical CI. N. Am. 53: 355-362. April 1973. 4. Ding-Shinn Chen, et. al.: Serum alpha,- fetoprotein in hepatocellular carcinoma. Cancer 779-783. August 1977. 5. Fortner J.G. et. al.: Surgery in Liver Tu- mors. Current Problems in Surgery. June 1972. 6. Goldsmith, H.. Hepatic Resection. Surgical Cl. N. Am. 53: 703-709. June 1973. 7. Kohn. J.: Method for the detection and identification of alpha,-fetoprotein in serum. J. of Clin. Path. 23: 733-735. Nov. 1970. 8. Lawrence, G.H. et. al.: Primary Carcinoma of the Liver. Am. J. of Surgery 112: 200-210. August 1966. 9. Tien-Yu Lin. Results of 107 Hepatic Lobec- tomies with Preliminary Report on the Use of a Clamp to Reduce Blood Loss. Ann. Surg. 177: 413-421. Apríl 1973. i
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