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Læknablaðið - 15.12.2011, Qupperneq 33

Læknablaðið - 15.12.2011, Qupperneq 33
Y F I R L I T utanríkisþjónustu ríkis á borð við ísland, hvort sem það hefur orðið fyrir tímabundnum skakkaföllum eða ekki, sé þróunarsam- vinna. Einfaldar forvarnir eins og þær sem framkvæma má með þró- unaraðstoð krefjast augljóslega ekki sérhæfðrar læknisfræðilegrar kunnáttu. Þær forvarnaraðgerðir má telja til almennrar baráttu gegn fátækt í heiminum. Fjöldalyfjagjafir hafa einnig þann kost að vera einfaldar í framkvæmd, svo sérfræðikunnáttu er ekki þörf við dreifingu lyfja. Því er það ekki svo að læknar þurfi að vera staddir á vettvangi til að hafa áhrif á framvindu sjúkdómanna sem um ræðir. Hins vegar koma gefendur fjármuna til VSÞ úr ýmsum áttum og hafa ekki alltaf forsendur til að meta í hvers konar verk- efni fjármagn vantar helst. Læknar, bæði hérlendis og erlendis, þurfa því að nýta áhrif sín og þekkingu til að leiðbeina gefendum og vera málsvari smitaðra, svo þessi vanrækti sjúklingahópur fái viðunandi greiningu, forvarnir og meðferð. íslendingar hafa allar forsendur til að vera mun virkari á þessum sviðum en nú. Við höfum mannafla, þekkingu, fjármuni og síðast en ekki síst áhuga. Fátt væri okkur verðugra en að nýta hann betur. Heimildir 1. Vanderelst D, Speybroeck N. Quantifying the lack of scientific interest in neglected tropical diseases. PLoS neglected tropical diseases 2010;4:e576. 2. Conteh L, Engels T, Molyneux DH. Socioeconomic aspects of neglected tropical diseases. Lancet 2010; 375: 239-47. 3. WHO. The global burden of disease: 2004 update; 2008. 4. King CH, Bertino AM. Asymmetries of poverty: why global burden of disease valuations underestimate the burden of neglected tropical diseases. PLoS neglected tropical diseases 2008;2:e209. 5. Gubler DJ. Epidemic dengue/dengue hemorrhagic fever as a public health, social and economic problem in the 21st century. Trends Microbiol 2002; 10:100-3. 6. Moran M, Guzman J, Ropars AL, et al. Neglected disease research and development: how much are we really spending? PLoS Med 2009;6:e30. 7. Neglected tropical diseases. 2009. who.int/neglected_ diseases/faq/en/index5.html. - júlí 2011. 8. Mendoza N, Li A, Gill A, Tyring S. Filariasis: diagnosis and treatment. Dermatol Ther 2009; 22:475-90. 9. Mathers CD, Ezzati M, Lopez AD. Measuring the burden of neglected tropical diseases: the global burden of disease framework. PLoS Negl Trop Dis 2007; l:ell4. 10. Enk CD. Onchocerciasis--river blindness. Clin Dermatol 2006; 24:176-80. 11. Bethony J, Brooker S, Albonico M, et al. Soil-transmitted helminth infections: ascariasis, trichuriasis, and hookworm. Lancet 2006; 367:1521-32. 12. Soil-transmitted helminths. 2010. who.int/intestinal_ worms/en/ - júlí 2011. 13. Steinmann P, Keiser J, Bos R, Tanner M, Utzinger J. Schistosomiasis and water resources development: systematic review, meta-analysis, and estimates of people at risk. The Lancet Infect Dis 2006; 6:411-25. 14. Parkin DM. The global health burden of infection-associated cancers in the year 2002. Int J Cancer 2006; 118:3030-44. 15. Jukes MC, Nokes CA, Alcock KJ, et al. Heavy schistosomiasis associated with poor short-term memory and slower reaction times in Tanzanian schoolchildren. Trop Med Int Health 2002; 7:104-17. 16. Skímisson K, Kolarova L. Sundmannakláði í Landmanna- laugum. Læknablaðið 2005; 91: 729-36. 17. Wright HR, Tumer A, Taylor HR. Trachoma. Lancet 2008; 371:1945-54. 18. David CV, Craft N. Cutaneous and mucocutaneous leishmaniasis. Dermatol Ther 2009; 22:491-502. 19. Desjeux P. Leishmaniasis: current situation and new perspectives. Comp Immunol Microbiol Infect Dis 2004; 27: 305-18. 20. Tarleton RL, Reithinger R, Urbina JA, Kitron U, Gúrtler RE. The Challenges of Chagas Disease - Grim Outlook or Glimmer of Hope? PLoS Med 2007; 4:1852-7. 21. Webster DP, Farrar J, Rowland-Jones S. Progress towards a dengue vaccine. Lancet Infect Dis 2009; 9:678-87. 22. Mandeville KL, Krabshuis J, Ladep NG, Mulder CJ, Quigley EM, Khan SA. Gastroenterology in developing countries: issues and advances. World J Gastroenterol 2009; 15:2839-54. 23. Stanley SL, Jr. Amoebiasis. Lancet 2003; 361:1025-34. 24. Marcos LA, DuPont HL. Advances in defining etiology and new therapeutic approaches in acute diarrhea. J Infect 2007; 55:385-93. 25. Portaels F, Silva MT, Meyers WM. Buruli ulcer. Clin Dermatol 2009; 27: 291-305. 26. Bamett ED. Yellow fever: epidemiology and prevention. Clin Infect Dis 2007; 44: 850-6. 27. Brun R, Blum J, Chappuis F, Burri C. Human African trypanosomiasis. Lancet 2010; 375:148-59. 28. Hopkins DR, Ruiz-Tiben E, Downs P, Withers PC, Jr., Roy S. Dracunculiasis Eradication: Neglected No Longer. Am J Trop Med Hyg 2008; 79:474-9. 29. Simarro PP, Jannin J, Cattand P. Eliminating human African trypanosomiasis: where do we stand and what comes next? PLoS Med 2008; 5: e55. 30. Metrics: Disability-Adjusted Life Year (DALY). 2010. who. int/healthinfo/global_burden_disease/metrics_daly/en/ - maí 2010. 31. Hotez PJ, Alibek K. Central Asia's Hidden Burden of Neglected Tropical Diseases. PLoS Negl Trop Dis 2011; 5: el224. 32. Burkot TR, Durrheim DN, Melrose WD, Speare R, Ichimori K. The argument for integrating vector control with multiple dmg administration campaigns to ensure elimination of lymphatic filariasis. Filaria J 2006; 5: 10. 33. Wang LD, Chen HG, Guo JG, et al. A strategy to control transmission of Schistosoma japonicum in China. N Engl J Med 2009; 360:121-8. 34. CfDCaP. Progress toward global eradication of dracunculiasis, January 2008-June 2009. Morb Mortal Wkly Rep 2009; 58:1123-5. 35. Lob-Levyt J, Affolder R, Rizzo I, Burgess C, Bchir A. A prescription for drug delivery. Nature 2007; 449:170-2. 36. Jauréguiberry S, Paris L, Caumes E. Acute schistosomiasis, a diagnostic and therapeutic challenge. Clin Microbiol Infect 2010; 16:225-31. 37. Hopkins AD. Ivermectin and onchocerciasis: is it all solved? Eye (Lond) 2005; 19:1057-66. 38. Parker M, Allen T. Does mass drug administration for the integrated treatment of neglected tropical diseases really work? Assessing evidence for the control of schistosomiasis and soil-transmitted helminths in Uganda. Health research policy and systems / BioMed Central 2011; 9: 3. 39. Enserink M. Global health. Some neglected diseases are more neglected than others. Science 2009; 323: 700. 40. WHO. World Malaria Report 2009; 2009. 41. Butler D. Lost in translation. Nature 2007; 449:158-9. 42. Hopkins AL, Witty MJ, Nwaka S. Mission possible. Nature 2007; 449:166-9. 43. WHO. Leprosy fact sheet. Wkly Epidemiol Rec 2010; 85: 46-8. 44. Ottesen EA, Hooper PJ, Bradley M, Biswas G. The global programme to eliminate lymphatic filariasis: health impact after 8 years. PLoS Negl Trop Dis 2008; 2: e317. 45. Singer PA, Bemdtson K, Tracy CS, et al. A tough transition. Nature 2007; 449:1 60-3. 46. Wolfson LJ, Gasse F, Lee-Martin SP, et al. Estimating the costs of achieving the WHO-UNICEF Global Immunization Vision and Strategy, 2006-2015. Bull World Health Organ 2008; 86:27-39. 47. The 0.7% target: An in-depth look. 2006. unmillenniumproject.org/press/07.htm - júlí 2011. 48. Þjóðhagsreikningar. 2010. hagstofa.is/Hagtolur/Thjod- hagsreikningar/Thjodhagsreikningar - júlí 2011. ENGLISH SUMMARY Neglected tropical diseases - review Kristjansson J, Gudmundsson S Neglected tropical diseases include a variety of infectious diseases. This review shortly describes the most common diseases. Those infected usually live at a low socioeconomic status and rarely have access to satisfactory health care. The neglected diseases are common and have a high burden of disease. In comparison to HIV, malaria and tuberculosis this group of diseases is in fact neglected. Certain diseases within the group are more neglected than others. Investment for research does not appear to be decided in proportion to burden of disease. Much can be gained by exterm- ination of these diseases. The solution is to integrate improvement of living standards and battling diseases. Iceland has a role to play. Key words: Neglected tropical diseases, DALY, development aid. Correspondence: Július Kristjánsson, juk2@hi.is LÆKNAblaðið 2011/97 697
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