Læknaneminn - 01.04.2016, Page 25

Læknaneminn - 01.04.2016, Page 25
Ri trý nt e fn i 25 Samantekt Glúten garnamein er bólgu sjúk dómur í þörmum og einkennist af sjálfs ofnæmi af völdum fæðu sem inni heldur glúten. Sjúkdómurinn er sérstak lega algengur í ein- stak lingum af norður-evrópskum upp runa og er lík lega van greindur. Einkenni glúten garna meins geta verið marg vís leg og eru oft ósértæk. Helstu einkenni sjúk dómsins eru lang vinnur niður gangur, þyngdar tap, kvið- verkir og skort seinkenni. Oft eru einkenni utan meltingar vegar meira áberandi en meltingar einkennin. Aukin áhætta er á öðr- um sjálfs ofnæmis sjúkdómum og krabba meini í meltingar vegi. Greining glúten garna meins fæst með mælingu á mót efnum gegn tTG, speglun á efri meltingar vegi og vefja sýnum úr skeifu görn. Glúten snautt fæði er besta með- ferðin og minnka einkenni hjá meiri hluta sjúklinga innan tveggja vikna. Heimildir 1. Di Sabatino A, Corazza GR. Coeliac disease. Lancet 2009;373(9673):1480–93. 2. Schuppan D, Zimmer K-P. The diagnosis and treatment of celiac disease. Dtsch Arztebl Int 2013;110(49):835–46. 3. Schuppan D, Junker Y, Barisani D. Celiac Disease: From Pathogenesis to Novel Therapies. Gastroenterology 2009;137(6):1912–33. 4. Rubio-Tapia A, Hill ID, Kelly CP, Calderwood AH, Murray JA. American College of Gastroenterology Clinical Guideline : Diagnosis and Management of Celiac. Am J Gastroenterol 2013;108(5):656–76; quiz 677. 5. Burger JPW, Roovers E a, Drenth JPH, Meijer JWR, Wahab PJ. Rising incidence of celiac disease in the Netherlands; an analysis of temporal trends from 1995 to 2010. Scand J Gastroenterol 2014;49(8):933–41. 6. Dubé C, Rostom A, Sy R, o.fl. The prevalence of celiac disease in average- risk and at-risk Western European populations: A systematic review. Gastroenterology 2005;128(4 SUPPL. 1):57–67. 7. Mustalahti K, Catassi C, Reunanen A, o.fl. The prevalence of celiac disease in Europe: results of a centralized, international mass screening project. Ann Med 2010;42(8):587–95. 8. Óladóttir GL, Guðjónsson H. Glútenóþol í görn á Íslandi - Faraldsfræðileg rannsókn 1992 - 2005. 2005. Óbirtar niðurstöður. 9. Farrell RJ, Kelly CP. Celiac sprue. N. Engl. J. Med. 2002;13(4):232–44. 10. Gheller-Rigoni AI, Yale SH, Abdulkarim AS. Celiac Disease: Celiac Sprue, Gluten- sensitive Enteropathy. Clin Med Res 2004;2(4):71–2. 11. Bolotin D, Petronic-Rosic V. Dermatitis herpetiformis. J Am Acad Dermatol 2011;64(6):1017–24. 12. Biesiekierski JR, Newnham ED, Irving PM, o.fl. Gluten causes gastrointestinal symptoms in subjects without celiac disease: a double-blind randomized placebo-controlled trial. Am J Gastroenterol 2011;106(3):508–14; quiz 515. 13. Hadithi M, von Blomberg BME, Crusius JBA, o.fl. Accuracy of serologic tests and HLA-DQ typing for diagnosing celiac disease. Ann Intern Med 2007;147(5):294–302. ÍSLE N SK A /SIA .IS LYF 79522 04/16 • Blóðþrýstingsmælingu • Blóðsykursmælingu • Blóðfitumælingu • Beinþéttnimælingu • Öndunarmælingu • Blóðrauðamælingu • Mælingu á súrefnismettun í blóði sjá nánar á lyfja.is lyfja.is Við bjóðum upp á eftirfarandi heilsufarsmælingar alla virka daga í Lyfju Lágmúla og Smáratorgi
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