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Læknablaðið - 15.01.1996, Page 52

Læknablaðið - 15.01.1996, Page 52
38 LÆKNABLAÐIÐ 1996; 82 bóluefnum gegn barnaveiki og stífkrampa samkvæmt núgildandi fyrirmælum um bólu- setningar. Vegna kröfu um lækkun á kostnaði við heil- brigðiskerfið er líklegt að verð á bóluefnum muni verða mikilvægasta atriðið við val á þeim í framtíðinni. Auk verðsins ættu þær spurning- ar sem settar voru fram hér að framan einnig að vera íhugunaratriði fyrir þá sem velja bólu- efni og ákveða hvatningarskammta. Þakkir Þakkir skulu færðar meinatæknum sem sent hafa H. influenzae stofna til sýklafræðideildar Landspítala sem og meinatæknum þar fyrir ómælda vinnu við hjúpgreiningar. Einnig þökkum við læknum á barnadeildum fyrir að- gang að sjúkraskrám sjúklinga með sjúkdóma af völdum Hib og Karli G. Kristinssyni dósent fyrir aðgang að safni nefkoksstroka. Hjúkrun- arfræðingum þökkum við upplýsingar um Hib bólusetningar barna sem veiktust af sjúkdóm- um af völdum Hib frá og með árinu 1989. HEIMILDIR 1. Jónsdóttir KE. Heilahimnubólga og aðrar alvarlegar sýkingar af völdum Haemophilus infiuenzae. Faraldurs- fræðilegt yfirlit 1974-1988. Heilbrigðisskýrslur 1988. Reykjavík: Landlæknisembættið, 1988. 2. Eskola J, Peltola H, Takala AK, Kayhty H, Hakulinen M, Karanko V, et al. Efficacy of Haemophilus influenze type b polysaccharide-diphtheria toxoid conjugate vac- cine in infancy. N Engl J Med 1987; 317: 717-22. 3. Ólafsson Ó, Jónsdóttir KE, Barreto L, Hansen H, Sig- thórsson Th. The launch of an infant Haemophilus influ- enzae type b immunisation programme in Iceland. 8th Congress on Circumpolar Health, Whitehorse, Yukon 1990. Arctic Med Res; Suppl. 5: 341-3. 4. Jónsdóttir KE, Steingrímsson Ó, Ólafsson Ó. Immuni- sation in Iceland against Haemophilus influenzae type b. Lancet 1992; ii: 252-3 (letter). 5. Jónsdóttir KE, Hansen H, Guðbjörnsdóttir H, Guð- mundsdóttir M, Ólafsson Ó, Jónasson M, et al. Epide- miology of Invasive Haemophilus infiuenzae b (Hib) disease in Iceland from 1974 and Impact of Vaccination Programme Launched in 1989. 9th Congress of Circum- polar Health Reykjavík 1993. Arctic Med Res 1994; 53/ Suppl. 2: 619-21. 6. Jónsdóttir K, Ríkharðsdóttir H. Meningókokka- og Hib berar meðal framhaldsskólanema í Reykjavík í janúar 1993. Óbirtar niðurstöður. 7. Kayhty H, Peltola H, Karanko V, Makela H. The Pro- tective level of Serum Antibodies to the Capslular Poly- saccharide of Haemophilus influenzae type b. J Infect Dis 1983; 147: 1100. 8. Anderson P. The protective level of Serum Antibodies to the Capsular Polysaccharide of Haemophilus influen- zae type b. J Infect Dis 1984; 149: 1034. 9. Kjeldsen K, Simonsen O, Heron I. Immunity against Diphtheria 25-30 Years after Primary Vaccination in Childhood. Lancet 1985; i: 900-2. 10. Takala AK, Eskola J, Leinonen M, Kayhty H, Nissinen A, Pekkanen E, et al. Reduction of Oropharyngeal Car- riage of Haemophilus influenzae Type b (Hib) in Chil- dren Immunized with an Hib Conjugate Vaccine. J In- fect Dis 1991; 164: 982-6. 11. Mohle-Boetani C, Ajello G, Breneman E, Deaver KA, Harvey C, Plikaytis BD, et al. Carriage of Haemophilus influenzae type b in children after widespread vaccina- tion with conjugate Haemophilus infiuenzae type b vac- cines. Pediatr Infect Dis J 1993; 12: 589-93. 12. Kauppi M, Eskola J. Kayhty H. Anti-capsular poly- saccharide antibody concentration in saliva after immu- nization with Haemophilus influenzae b type conjugate vaccines. Pediatr Infect Dis J 1995; 14: 286-94. 13. Robbins JB, Schneerson R, Argaman M, Handzel ZT. Haemophilus infiuenzae type b: Disease and Immunity in Humans. NIH Conference. Ann Int Med 1973; 78: 259-69. 14. Ward J. Prevention of invasive Haemophilus influenzae type b disease: Lessons from vaccine efficacy trials. Vac- cine 1991; 9/Suppl.: S17-24. 15. Black SB, Shinefield HR and the Kaiser Permanente Pediatric Vaccine Study group. Immunization with oli- gosaccharide conjugate Haemophilus influenzae type b (HbOC) vaccine on a large health maintenance orga- nization population: extended follow-up and impact on Haemophilus influenzae disease epidemiology. Pediatr Infect Dis J 1992; 11: 610-3. 16. Booy R, Hodgson S, Carpenter L, Mayon-White RT, Slack MPE, Macfarlane JA, et al. Efficacy of Haemo- philus influenzae type b conjugate vaccine PRP-T. Lan- cet 1994; 344: 362-6. 17. Ward J, Brenneman G, Letson G, Heyward WL and the Alaska Haemopliilus influenzae vaccine study group. Limited efficacy of a Haemophilus influenzae type b Conjugate vaccine in Alaska native infants. N Engl J Med 1990; 323: 1393-1401. 18. Schneerson R, Robbins JB, Parke JC, Bell C, Schlessel- man JJ, Sutton A, et al. Quantitative and qualitative analyses of Serum Antibodies Elicited in Adults by Hae- mophilus influenzae Type b and Pneumococcus Type 6A Capsular Polysaccharide-Tetanus Toxoid Conjugates. Infect Immun 1986; 52: 519-28.
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