Læknaneminn


Læknaneminn - 01.10.1996, Qupperneq 62

Læknaneminn - 01.10.1996, Qupperneq 62
I Helicobacter pylori - yfirlitsgrein inant H. pylori ureasa og hefur það reynst veita góða vörn í músum (92), Auk þess að koma í veg fyrir H. pylori sýkingar með bólusetningum hefur verið reynt að uppræta H. pylori sýkingar í músum með bólusetrtingum. Við þær til- raunir var ureasa undireining B gefin p.o. og voru nið- urstöðurnar mjög lofandi (93). Þessar rannsóknir og fleiri svipaðar gefa góðar vonir um að í framtíðinni verði hægt að bólusetja gegn H. pylori og mögulega útrýma þessari sýkingu sem í dag er ein algengasta króníska bakteríusýkingin sem hrjáir mannkynið. NIÐURLAG Helicob.aeter pylori sýking er ein algengasta króníslca bakteríusýkingin sem hrjáir mannkynið. Þó tilvist bakteríunnar hafi ekki verið þekkt nema í 14 ár hafa þau ár verið viðhurðarrík. Gífulegar framfarir hafa orð- ið í meðferð ætisára á þessum tíma. Framtíðin á síðan eftir að leiða í ljós hvort hægt verði að meðhöndla H. pylori sýkingar á einfaldan hátt, eða jafnvel bólusetja gegn bakteríunni. Ef hægt væri að útrýma H. pylori hér á landi má búast við að það myndi ekki einungis nánast útrýma ætisárum, heldur einnig hugsanlega fækka tilfellum af magakrabbameini verulega. HEIMILDIR: 1. Kornberg HL, Davies RE, Wood DR: The activity and function of gastric urease in the cat. Bioehem J 1954, 56.'363-372 2. Von Korff RW, GUck D: Role.of urease in the gastric mucosa. II. In vitro studies with isotopic urea on frog mucosa. Am J Physiol 1951, 165:688-694 3. Zbarsky SH, Wright WD: The metabolism of C14- urea in the rat. Can J Med Sci. 1953,31:151-161 4. Bode G, Malfertheiner P, Lehnhardt G, Nilius M, Ditschuneit H: UltrastructuraJ localization of urease of Helicobacter pylori. Med Microbiol Immunol 1993, 182:233-242 5. Hazetl Sl, Evans DJ jr,. Graham DYí Helico.bacter pylori catalase. J Gen Microbiol 1991, 13,7:57 6. Inamoto Y, Hamanaka S, Hamanaka Y, Nagate T, Kondo I, Takemoto T, Okita K: Lipid eomposition and fatty acid analysis of Helicobacter pylori. J Gastroenterol 1995, 30(3);315<-318 7. Megraud F: Microbiological eharacteristi'cs of Campylobaeter pylori. Eur J Gastroenterol Hepatol 1989 1:5-12 8. Blaser MJ: The baeteria behind' ulcers. Scientific American 1996, February: 92-97 9. Karl G. Kristinsson, Erla Sigvaldadóttir, Bjarni Þjóðleifsson: Al- gengi mótefna gegn Helicobacter pylori á Islandi. Læknablaðið 1996, 82:366-370. 10. Malaty HM, Kiro JG, Kim SD, Graham DY: Prevalence of Helic- obacter pylori infection in Korean children: inverse relation to soci- oeconomic status despite a uniformly high prevalence in adults. Am J Epidemiol 1996, 143:257-262 11. Neale KR, Logan RP: The epidemiology and transmission of Helic- obacter pylori infeccion in children. Alim Pharm Ther 1995, 9 Suppl 2:77-84 12. Whitaker CJ, Dubiel AJ, Galpin OP: Social and geographic factors in Helicobacter pylori infection. Epidemiol Infect 1993, 111:63-70 13. Replogle ML, Glaser Sl, Hiatt RA, Parsonnet J: Biologic sex as a factor for Helicobacter pylori infecton in healthy young adults. Am J Epidemiol 1995, l42(8):856-863 14. Shahamat M, Mai U, Paszko-Kolva C, Kessel M, Colwell RR: Use of autoradiography to assess viability of Helicobacter pylori in wa- ter, Appl Environ Microbiol 1993, 59:1231-1235 15. Vanzweet AA, Thijs JC, Kooistrasmid AMD, Schirm J, Snijder JAM: Use ofPCR with feces for detection of Helicobacter pylori in- fection in patients. J Clin Microbiol 1994, 32:1346-134810. 16. Luman W, Alkout AM, Blackwell CC, Weir DM, Palmer KR: Helicobacter pylori in the mouth - negative isolation from dental plaque and saliva. Eur J Gastroenterol & Hepatol 1996, 8:11-14 17. Handt LK, Fox JG, Dewhirst FE, Fraser GJ, Paster BJ, Yan LL, Rozmiarek H, Rufo R, Stalis IH: Helicobacter pylori isolated from the domestic cat: public health implication. Infection and imm- unity 1994, 62:2367-2374 18. Axon; ATR: The transmission of Helicobacter pylori: which theory fits the facts? Eur J Gastroenterol & Hepatol 1996, 8:1-2 19. Axon: Acute infection with Helicobacter pylori. In Helicobacter pylori basic mechanisms to clinicai cure. London: Kluwer Academ- íq 1994:407-412 20. Tytgat GNJ; Endoscopic transmission of Helicobacter pylori. Ali- ment Pharmacol Ther 1995; 9:105-110 21. Taylor D, Blaser M: The epidemiology of Helicobacter pylori in- fection. Epidemiol Rev 1991. 13:40-59 22. Wihoite SL, Ferguson D Jr, Soike DR , et al: Increased prevalence of Helicobacter pylori antibodies among nurses. Arch Intern Med 1993. 153:708-712 23. Luzza F, Maletta M, Imeneo M, Fabiano E, Doldo P, Biancone L, Pallone F: Evidence against an increased risk of Helicobacter pylori infection in dentists: a serological and salivary study. Eur J Gastroenterol Hepatol 1995, 7(8): 773-779 24. Goodwin CS, Blincow ED, Warren JR et al: Evaluation of culture techinques for isolating Campylobacter pyloridis from endoscopic biopsies, of gastric mucosa. J Clin Pathol 1985, 38:1127 25. Westblom TU: The comparative value of different diagnostic tests for helicobacter pylori. In Helicobacter pylori: biology and clinical practice. Boca Raton, Florida CRCPress; 1993:329-342 26. Schrader JA, Peck HV, Notis WM, Shaw P, Venezia RA: A role for culture in diagnosis of Helicobacter pylori-related gastric disease. Am J Gastroenerol 1993, 88:1729-1733 27. Sim JG, Kim EC, Seo JK: The role of serology in the diagnosis of Helicobacter pylori infection in children. Clin Pediatrics 1995, 34(9):458-462 28. Meyer B, Werth B, Beglinger C, Dill S, Drewe J, Vischer WA, Eggers RH, Bauer FE, Stadler GA: Helicobacter pylori infection in healthy people: a dynamic process? Gut 191,3 2,347-350 29. Hussan MO, Gottrand F, Turck D et al: Detection of H. pylori in saliva using monoclonal antibody. J Med Microbiol Virol Parasitol 1993 279:466 30. Eggers RH, Kulp A, Tegeler R, Liidtke FE, Lepsien G, Meyer B, Bauer FE: A methodological analysis of the 13C-urea breath test for the detection Helicobacter pylori infections: high sensitivity and specificity within 30 min using 75 mg of 13C-urea. Eur J Gastroenerolo Hepatol 2:437-444, 1990 31. Thijs WJ, Thijs JC, Kleibeyker JH, Elzinga H, Stellaard F: Evalu- ation of clinical and home performance of the 13C-urea breath test for the detection of Helicobacter pylori. Eur J Gastroenterol Hepatol 1995, 7(7):603-607 32. Slomiansky A, Schubert T, Cutler AF: 13C-urea breath test to con- firm eradication of Helicobacter pylori. AmJ Gastroenterol. 1995, 90(2)224-226 33. Moskowitz M, Konikoff FM, Peled Y, Santo M, Hallak A, Buja- nover Y, Tiomny E, Gilat T: High Helicobacter pylori numbers are associated with low eradication rate after triple therapy. Gut 1995, 36(6):845-847 34. Westblom TU, Phadnis S, Yang P, Czinn SJ: Diagnosis of Helic- obacter pylori infection by means of a polymerase chain reaction assay for gastric juice aspirates. Clin Infect Dis 1993, 16:367-371 35. Patel P, Khulusi S, Mendall MA, Lloyd R, Jazrawi R, Maxwell JD, Northfield TC: Prospective screening of dyspeptic patients by Helicobacter pylori serology. Lancet, 1995, 346(8986): 1315-1318 LÆKNANEMINN 52 2. tbl. 1996, 49. árg.
Qupperneq 1
Qupperneq 2
Qupperneq 3
Qupperneq 4
Qupperneq 5
Qupperneq 6
Qupperneq 7
Qupperneq 8
Qupperneq 9
Qupperneq 10
Qupperneq 11
Qupperneq 12
Qupperneq 13
Qupperneq 14
Qupperneq 15
Qupperneq 16
Qupperneq 17
Qupperneq 18
Qupperneq 19
Qupperneq 20
Qupperneq 21
Qupperneq 22
Qupperneq 23
Qupperneq 24
Qupperneq 25
Qupperneq 26
Qupperneq 27
Qupperneq 28
Qupperneq 29
Qupperneq 30
Qupperneq 31
Qupperneq 32
Qupperneq 33
Qupperneq 34
Qupperneq 35
Qupperneq 36
Qupperneq 37
Qupperneq 38
Qupperneq 39
Qupperneq 40
Qupperneq 41
Qupperneq 42
Qupperneq 43
Qupperneq 44
Qupperneq 45
Qupperneq 46
Qupperneq 47
Qupperneq 48
Qupperneq 49
Qupperneq 50
Qupperneq 51
Qupperneq 52
Qupperneq 53
Qupperneq 54
Qupperneq 55
Qupperneq 56
Qupperneq 57
Qupperneq 58
Qupperneq 59
Qupperneq 60
Qupperneq 61
Qupperneq 62
Qupperneq 63
Qupperneq 64
Qupperneq 65
Qupperneq 66
Qupperneq 67
Qupperneq 68
Qupperneq 69
Qupperneq 70
Qupperneq 71
Qupperneq 72
Qupperneq 73
Qupperneq 74
Qupperneq 75
Qupperneq 76
Qupperneq 77
Qupperneq 78
Qupperneq 79
Qupperneq 80
Qupperneq 81
Qupperneq 82
Qupperneq 83
Qupperneq 84
Qupperneq 85
Qupperneq 86
Qupperneq 87
Qupperneq 88
Qupperneq 89
Qupperneq 90
Qupperneq 91
Qupperneq 92
Qupperneq 93
Qupperneq 94
Qupperneq 95
Qupperneq 96
Qupperneq 97
Qupperneq 98
Qupperneq 99
Qupperneq 100
Qupperneq 101
Qupperneq 102
Qupperneq 103
Qupperneq 104
Qupperneq 105
Qupperneq 106
Qupperneq 107
Qupperneq 108
Qupperneq 109
Qupperneq 110
Qupperneq 111
Qupperneq 112
Qupperneq 113
Qupperneq 114
Qupperneq 115
Qupperneq 116
Qupperneq 117
Qupperneq 118
Qupperneq 119
Qupperneq 120
Qupperneq 121
Qupperneq 122
Qupperneq 123
Qupperneq 124
Qupperneq 125
Qupperneq 126
Qupperneq 127
Qupperneq 128
Qupperneq 129
Qupperneq 130
Qupperneq 131
Qupperneq 132

x

Læknaneminn

Direct Links

Hvis du vil linke til denne avis/magasin, skal du bruge disse links:

Link til denne avis/magasin: Læknaneminn
https://timarit.is/publication/1885

Link til dette eksemplar:

Link til denne side:

Link til denne artikel:

Venligst ikke link direkte til billeder eller PDfs på Timarit.is, da sådanne webadresser kan ændres uden advarsel. Brug venligst de angivne webadresser for at linke til sitet.