Læknablaðið : fylgirit - 01.05.1982, Page 50

Læknablaðið : fylgirit - 01.05.1982, Page 50
48 The incidence among females is relatively high, there being a male; female ratio of 2,8:1 from 1931—1954, 2,1:1 from 1955—1964 and 1,5:1 from 1965—1974. There have been about twice as many lung carcinomas among females in the urban as in the rural areas. The significance of these figures may lie in the fact, that smoking among females occurs mainly in the urban areas and is reiatively much less common in the rural group. The National Cancer Registry was establis- hed in 1955 and since then all the cases have come from this institute’s files as well as from the files of the various hospitals throughout the country. The hospital records of all the patients were studied and the macroscopic descriptions of the surgically reseeted lungs and necroscopies were reviewed. All available microscopie slides have been re-examined by one pathologist and the tumours classified histologically according to the WHO’s classification. There is a prepon- derance of small cell anaplastic carcinoma 33,4% and adenocarcinoma 26,5% in this series. Ep'.dermoid or squamous cell carcinoma were found in only 24,7% per cent of cases and large cell undifferentiated carcinoma in 15,4%. During the period 1955—1974, 143 major surgical procedures were performed for lung cancer in Iceland; 68 explorative thoracotomies and 75 resections. The operability rate changed from 35,3% in the first half of this period to 32% in the second half and the resectability rate rose from 44% to 58% respect, due to fewer fruitless thoractomies. Calculated from the total number of lung cancer patients the resectability rate rose from 15,4 per cent to 18,6 per cent in those two tcn years periods. The extent of the resections was as follows: Pneumonectomies 58,7%, lobeetomies 38,6% and segmental resections 2,7%. Post operative mortality rate (30 days) is 4% in the resected series and 5,9% in the group of exploratory thoracotomies. In the resected series the five year survival rate is 29,3 per cent which is a total salvage rate of 5,1 per cent. Prognosis is most favourable for patients with squamous cell carcinoma, 40 per cent were resected with 44 per cent five year survival which means 17,6 per cent five year survival of all patients who had this histologic type of cancer. Prognosis for patients with the more rapidly growing lung carcinomas is, however, not quite hopeless as there are a few 5 year survivors even in the small cell anaplastic group. HEIMILDASKRÁ 1. Þórarinsson, Hjalti: Læknablaðið 1962, 79- 93. 2. Ringertz, N. (Ed.): Cancer Incidence in Finland, Iceland, Norway and Sweden: Acta path. Microbiology Scand. Section A, suppl. 224, 1971, p. 12. 3. Ochsner, A., Ochsner, A. Jr., H’Doubler, C. and Blalock, J.: Bronchogenic Carcinoma: Diseases Of The Chest, Volume XXXVII, January 1960. 4. Thompson, V.C.: Tumores Of The Lung: Clinical Surgery 5, London Butterworth 1965 (p. 130-131). 5. Sterling, T. D.: A Critical Reassesment of the Evidence Bearing on Smoking as a Cause of Lung Cancer: AJPH September 1965, Vol. 65, no. 9, p. 939-953. 6. Thorarinson, H.: Carcinoma of the lung in Iceland: Scand. J. Thor. Cardiovasc. Surg. 3:31-38, 1969. 7. Surgical Diseases of the Chest: Edited by Brian Blades, M.D. The C.V. Mosby Com- pany 1961, St. Louis, p. 150-167. 8. Fréttabréf um heilbrigðismál, nr. 5, april 1950. 9. Jónsson, Björn L.: Reykingar barna i Reykjavík: Heilbrigt líf, 1963: 16:35. 10. Sigurðsson, Jón: Reykingavenjur barna og unglinga í Reykjavík: Frá borgarlæknis- embættinu i Reykjavík, ágúst 1975. 11. Guðmundsson, H., Björnsson, O.J., Ólafsson, Ó.: Könnun á tóbaksneyslu Islendinga árin 1960 til 1975: Heilbrigðismál, rit nr. 2, 1975. 12. Shields, T.W. and Higgins, G.A. Jr. (1974): Minimal Pulmonary Resection in Treatment of Carcinoma of the Lung: Archives of Surgery, 108, 420. 13. le Roux, B.T. (1972): Management of Bron- chial Carcinoma by Segmental Resection: Thorax, 27, 70. 14. Jensik, R.J., Faber, L.P., Milloy, F.J. and Monson, D.O. (1973): Segmental Resection for Lung Cancer: Journal of Thoracic and Cardiovascular Surgery 66, 563. 15. Jensik, R.J., Penfield, F. and Kittle, C.F.: Segmental Resection for Bronchogenic Car- cinoma: The Annals of Thoracic Surgery, vol. 28, 5, 1969. 16. Myron J. Jacobson, Lloyd Sand, Robert, T. Fox and Willian Lees: A Comparison of Wedge and Segmental Resection of the Lung: Thorax (1976 ) 31, 365. 17. Overholt, H.R., Neptune, W.B. and Ashraf, M.M.: Primary Cancer of the Lung: The Annals of Thoracic Surgery, vol. 20, no. 5, 1975. 18. Wilkins, W. Jr., Scannell, J.G. and Graver, J.G.: Four Decades of Experience with Re- sections for Bronchogenic Carcinoma at the Massachusetts General Hospital: Th. J. of Thoracic & Carcinoma at the Massachu- setts General Hospital: Th. J. of Thoracic & Cardiovasc. Surgery, vol. 76, 3, 1978. 19. Bennett, W. and Smith, R.A.: Segmental Resection for Bronchogenic Carcinoma: A Surgical Alternative for the Compromised Patients: The Annals of Thoracic Surg., vol. 27, 2, 169-72, 1979. 20. Bergh, N.P. and Scherstén, T.: Broncho- genic Carcinoma; A Follow-up Study of a Surgically Treated Series with Special Re- ference to the Prognostic Significance of

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