Læknablaðið - 15.10.1994, Blaðsíða 13
LÆKNABLAÐIÐ 1994; 80
361
hefur brottnám eggjastokka í för með sér
hækkun á Hb-styrk í blóði (30) og stórir
skammtar kvenhormóna framkalla lækkun
(31). Sú væga hækkun Hb í sermi sem fannst
hjá konurn um og eftir tíðahvörfin kemur vel
heim og saman við framangreindar niðurstöð-
ur í rottunum og þá hækkun í karlhormóna/
kvenhormóna hlutfallinu sem kemur upp úr
tíðahvörfum.
HEIMILDIR
1. Daly MP. Anemia in the elderly. Am Fam Physician
1989; 39: 129-36.
2. Nilsson-Ehle H, Jagenburg R, Landahl S, Svanborg A,
Westin J. Haematological abnormalities and reference
intervals in the elderly. Acta Med Scand 1988; 224:
595-604.
3. Zauber NP, Zauber AG. Hematologic data of healthy
very old people. JAMA 1987; 257: 2181-4.
4. Dallman PR, Yip R, Johnson C. Prevalence and causes
of anemia in the United States, 1976 to 1980. Am J Clin
Nutr 1984; 39: 437-45.
5. Milman N. Andersen HC, Pedersen NS. Serum ferritin
and iron status in 'healthy’ elderly individuals. Scand J
Clin Lab Invest 1986; 46: 19-26.
6. Challand GS, Michaeloudis A, Watfa RR. Coles SJ,
Macklin JL. Distribution of haemoglobin in patients
presenting to their general practitioner, and its correla-
tion with serum ferritin. Ann Clin Biochem 1990; 27:
15-20.
7. Kruger A. The limits of normality in elderly patients.
Bailliéres Clin Haematol 1987; 1: 271-89.
8. Lipschitz DA, Mitchell CO, Thompson C. The anemia
of senescence. Am J Hematol 1981; 11: 47-54.
9. Earney WW, Earney AJ. Geriatric hematology. J Am
Geriatr Soc 1972; 20: 174-7.
10. Lipschitz DA, Udupa KB, Milton KY, Thompson CO.
Effect of age on hematopoiesis in man. Blood 1984; 63:
502-9.
11. Salive ME, Comoni-Huntley J, Guralnik JM, Phillips
CL, Wallace RB. Ostfeld AM. Anemia and hemoglobin
levels in older persons: Relationship with age, gender,
and health status. J Am Geriatr Soc 1992; 40: 489-96.
12. Hoffmann RG. Statistics in the practice of medicine.
JAMA 1963; 185: 864-73.
13. Solberg HE. Establisment and use of reference values.
In: Tietz NW. ed. Textbook of clinical chemistry. Phila-
dclphia: Saunders, 1986: 356-86.
14. World Health Organization. Nutritional anaemias: re-
port of a WHO scientific group. Technical report series,
no. 405. Geneva: World Health Organization, 1968.
15. Monthly Statistics. Reykjavík: Statistical Bureau of Ice-
land, 1991; 76: 332-6.
16. Beck HJ, Kjeld JM. Notkun heimilis- og hjartalækna á
rannsóknum í efna- og blóðmeinafraeði. Læknablaðið
1992; 78: 279-85.
17. Jonsson JJ, Johannesson GM, Sigfusson N, Magnusson
B, Thjodleifsson B, Magnusson S. Prevalence of iron
deficiency and iron overload in the adult Icelandic pop-
ulation. J Clin Epidemiol 1991; 44: 1289-97.
18. Poole JCF, Summers GAC. Correction of ESR in anae-
mia. Experimental study based on interchange of cells
and plasma between normal and anaemic subjects. Br
Med J 1952; 1: 353-6.
19. Miller A, Green M, Robinson D. Simple rule for calcu-
lating normal erythrocyte sedimentation rate. Br Med J
1983; 1: 266.
20. Crawford J, Eye-Boland MK, Cohen HJ. Clinical utility
of erythrocyte sedimentation rate and plasma protein
analysis in the elderly. Am J Med 1987 ; 82: 239-46.
21. Hanger HC, Sainsbury R, Gilchrist NL, Beard MEJ.
Erythrocyte sedimentation rates in the elderly: a com-
munity study. N Z Med J 1991; 104: 134-6.
22. Shahidi NT. Androgens and erythropoiesis. N Engl J
Med 1973; 289: 72-80.
23. Clark HJ, Schrader WT, O’Malley BW. Mechanism of
action of steroid hormones. In: Wilson JD, Foster DW,
eds. Williams textbook of Endocrinology. 8th ed. Phila-
delphia: Saunders, 1992: 35-90.
24. Weber JP, Walsh PC, Peters CA. Spivak JL. Effect of
reversible androgen deprivation on hemoglobin and se-
rum immunoreactive erythropoietin in men. Am J He-
matol 1991; 36: 190-4.
25. Hamilton JB. The role of testicular secretion as indicat-
ed by the effects of castration in man and by studies of
pathological conditions and the short lifespan associated
with maleness. Rec Prog Horm Res 1948; 3: 257-322.
26. Tenover JS. Effects of testosterone supplementation in
the aging male. J Clin Endocrinol Metab 1992; 75:
1092-8.
27. Powers JS, Lichtenstein MJ, Collins JC, Krantz SB,
Greene HL, Buchholz T. Serum erythropoietin in
healthy older persons. J Am Geriatr Soc 1989; 37: 388-9.
28. Vermeulen A. Androgens in the aging male. J Clin
Endocrinol Metab 1991; 73: 221-4.
29. Jaffe RB. The menopause and perimenopausal period.
In: Yen SCC, Jaffe RB, eds. Reproductive endocrinol-
ogy: Physiology, pathophysiology and clinical manage-
ment. 2nd ed. Philadelphia: Saunders, 1986: 406-23.
30. Gimzell CA, Sjostrand T. The effect of the gonads on
the total amount of haemoglobin and blood volume in
rats. Acta Endocrinol 1956; 21: 86-96.
31. Dukes PP. Goldwasser E. Inhibition of erythropoiesis
by estrogens. Endocrinology 1961; 69: 21-9.