Læknaneminn - 01.04.2008, Síða 93

Læknaneminn - 01.04.2008, Síða 93
2000. Implementation of VCT and ARV treatment was observed, data collected from Health Management Information System (HMIS) andother statistical resources, and interviews conducted with health workers involved. Additional information was sought in local University libraries, national and international reports and guidelines. Statistical data and analysis was conducted in Excel for Windows v2003. The study was approved by ICEIDA and the MBCH project management. Result: Ihe HlV-prevalence in Malawi is estimated 14% in the age-group 15- 49 years. The national policy is to increase the access to VCT and ARV. VCT clinic has been open at MBCH since April 2005, the first of its kind in the area outside the District hospital in Mangochi. In total, 5043 people (about 9% of the target population) have attended the VCT in the whole health area. Among them 1257 (24.9%) were HlV-positive. Among the people tested, 2542 (50.4%) were pregnant women ofwhom 392 (15.4%) were positive. At MBCH the most common reasons for attendance are voluntary testing (39%), pregnancy (56%), and opportunistic infections (3%). Increasingly people attend for PMTCT rather than VCT. Since June 2006, 317 persons have initiated ARV treatment. Of these 18 (5.7%) have died, 6 (1.9%) have dropped out and 3 (0.9%) where transferred out. In the period, 111 children born to HlV-positive mother have received nevirapine as prophylaxis. Health workers complained mostly of limited space and heavy work load. New facilities for the services are in its final phase of construction. Conclusions: HIV/AIDS is a serious health problem in Malawi. Global efforts to offer VCT and ARV are reaching the rural periphery of the Malawian health system. The importance of VCT should be stressed in health information while PMTCT should continue and strengthened. Access to ARV treatment and continuous supplies of drugs needs to be secured. Improved facilities funded by ICEIDA contribute to better VCT and ARV services to the rural population involved, and are in line with the MDGs. Memory of self-related emotional stimuli in high and low ruminators Katrin Jonsdottirl, Emma Pegg2 and Bill Deakin2 Objective: Rumination is the tendency to focus passively and repetitively on one’s own thoughts, feelings, problems and symptoms of depression. Studies have showed that it predicts both subclinical symptoms of depression and depressive disorders. Women are approximately twice as likely as men to show depression and the differences might be because of rumination. Considering that rumination involves sustained or repetitive negative thoughts it is expected to result in sustained brain activity which could affect a range of cognitive tasks by occupying the necessary brain circuits. A number of studies have shown link between rumination and cognitive deficits, supporting that theory. However, it has been hypothesised that if memory was tested for a topic that was the content of rumination, rumination should increase recall, as the process of rumination should have over-consolidated the memory. Emotionally charged materials have been found to elicit higher levels of recall than neutral materials which could be because of increased tendency for people to ruminate on emotionally charged stimuli. In a recent study, low and high ruminative volunteers were given partly insoluble problem solving tasks and it was thought that high ruminators would ruminate more than the low ruminators about their failure. In a surprise recognition test for stimuli used in the tasks high ruminators did significantly better than low ruminators. However, low ruminators did significantly better on an unrelated cognitive task. We wanted to replicate the results of the previously described experiment, but this time using emotional stimuli and we are expecting high ruminators to recall more of the emotionally valenced stimuli, especially the negative stimuli. Material and Methods: 33 healthy volunteers, 17 low ruminators and 16 high ruminators completed a battery of computerised cognitive tasks and personality questionnaires. First they had to rate how much 20 positive and 20 negative emotionally valenced words applied to them on the scale from one to four. Later, in a surprise word recognition task, they were shown a series of words and asked to identify whether the words had been presented in the first task or not. Results: Low and high ruminative groups were well characterised. There were significant differencesbetween the two groups on symptoms of depression (t(16.409)=-8.084, p<0.001) and neuroticism personality trait (t(31)=- 7.624, p<0.001). This is consistent with the literature. In addition, there was significant difference between how the groups rated themselves on both negatively valenced words (F(l, 29)=45.833, p<0.001) and positively valenced words (F(l,29)=19.893, p<0.001) in the first task. Initially, two factor anova showed significant main effects of rumination group and gender on positive word recognition, and a significant main effect of gender on overall word recognition. However, there was no significant difference on word recognition, between neither low and high ruminators nor genders, when two outliers were taken into account. Conclusions: Low and high ruminative groups have the characteristics expected and interestingly rate themselves differently on the first task. But the word recognition taslc showed no significant difference which could be result of ceiling effects or that the emotionally valenced words were not subjects of rumination in the participants. Læknaneminn 93
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