Læknablaðið : fylgirit - 05.01.2015, Page 95

Læknablaðið : fylgirit - 05.01.2015, Page 95
X V I I V Í S I N D A R Á Ð S T E F N A H Í F Y L G I R I T 8 2 LÆKNAblaðið/Fylgirit 82 2015/101 95 registry at Landspitali and interviews with patients. The study period was 2009-2013. Discontinuation was categorized into two sets. The first one included cases where treatment was completely discontinued or switched to a different TNFα inhibitor. The second set included cases where treatment was temporarily discontinued (≥ 112 days) and subse- quently resumed with the same TNFα inhibitor. Results: Of the 513 patients that were included in the study, 283 patients discontinued treatment, 229 completely or switched to other drug (304 occasions) and 54 discontinued temporarily their TNFα treatment (74 occasions). The most common reasons for discontinuation of treatment were an inadequate response to treatment (36.2%) and adverse events (32.6%). The latter was also the most common reason for temporal treatment discontinuation (28.4%), infection being the far most common (76.2%). In cases of discontinuation/switch of treatment, infliximab was most commonly discontinued (45.7%) while teatment with etanercept was most commonly temporarily discontinued (64.9%). Conclusions: Inadequate response and adverse events are the most common reasons why RA and PsA patients discontinue TNFα inhibitor treatment and infliximab is the drug that is most commonly discont- inued. However when patients temporarily stop treatment, infection is the main reason and the drug most commonly involved is etanercept. V 122 Fóðrun heilgóma Ævar Pétursson, Svend Richter Tannlæknadeild Háskóla Íslands aevarp@gmail.com Inngangur: Oft er hægt að fóðra eldri heilgóma í stað endursmíði þeirra. Fóðrun heilgóma er því snar þáttur í heilgómagerð. Engar rannsóknir hafa verið gerðar hér á landi til að skoða starfshætti tannlækna og tann- smiða við fóðrun, samvinnu þessara stétta og hvort framkvæmd fóðr- unar standist þær kröfur sem gerðar eru hér nú. Efniviður og aðferðir: Spurningalisti var sendur tannlæknum í Tannlæknafélagi Íslands og 20 tannsmiðum í Tannsmiðafélag Íslands sem valdir voru af handahófi. Notast var við megindlega aðferðafræði. Gagnaúrvinnsla var unnin á SurveyMonkey® og Excel (Microsoft Corporation). Niðurstöður: Af 284 tannlæknum svöruðu 134 (47,2%) en allir tann- smiðir (100%). 90,1% tannlækna starfa við heilgómagerð. 45% tannsmiða notar alltaf kaldhert plast við fóðrun, 15% stundum en 20% aldrei. Þetta er óháð óska meirihluta tannlækna að fóðrun sé gerð samdægurs (alltaf 66,7%, oft 21,1%). Flestir tannlækna segjast gefa tannsmiðum leiðbein- ingar um hönnun afturmarka efri heilgóms en tannsmiðir kannast ekki við það. Langalgengasta mátefni var Xantopren (50,0%) en næst komu President og Impregum (12,5% hvort). Compound var algengast til mótunar brúna (60,7%). 8,1 % tannlækna fræsir ekki af brúnum og mótar á ný við fóðrun. Tannlæknar telja að þeir noti relining alltaf eða oft í 78,3% tilfella og tannsmiðir að þeir geri relining í 95,0% tilfella Ályktanir: Tannsmiðir fóðra frekar með kaldfjölliðuðu plasti en hita- fjölliðuðu. Ekki er fylgni á milli þess að tannlæknar vilji að fóðrun sé gerð samdægurs og að tannsmiðir noti kaldfjölliðað plast. Tannlæknum og tannsmiðum ber ekki saman hvor ákveði afturmörk efri heilgóms eða algengi relining á móti rebasing.
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