Læknablaðið - 15.02.2001, Blaðsíða 21
FRÆÐIGREINAR / RISTILKRABBAMEIN
og þroskunargráðu æxla, þannig að æxli í hægri hluta
ristils voru á hærra Dukes stigi og verr þroskuð en
æxli í vinstri hluta ristils. Aldrich og félagar komust að
svipaðri niðurstöðu (10).
Þakkir
Höfundar þakka Þorgeiri Þorgeirssyni yfirlækni á
meinafræðideild Fjórðungssjúkrahúss Akureyrar
fyrir aðgang að skriflegum gögnum meinafræði-
deildarinnar og vefjasýnum til endurskoðunar. Helgi
Sigvaldason fær þakkir fyrir veitta aðstoð við
tölfræðiúrvinnslu. Krabbameinsskrá Krabbameins-
félags Islands færum við þakkir fyrir upplýsingar um
greinda einstaklinga.
Vísindasjóður Krabbameinsfélags Islands og
Vísindasjóður Landspítalans fá þakkir fyrir styrkveit-
ingar til rannsóknarinnar.
Heimildir
1. Hamilton SR, Vogelstein B, Kudo S, Riboli E, Nakamura S,
Hainaut R Carcinoma of the Colon and Rectum. In: Hamilton
SR, Aaltonen LA, eds. Pathology & Genetics of Tumours of
the Digestive System. Lyon: IACR Press; 2000: pp 105.
2. Histological Typing of Intestinal Tumours. 2nd ed.
Collaboration with pathologists in 9 countries. Intemational
Histological Classification of Tumours. Springer-Verlag, Berlin,
Heidelberg, New York, London, Paris, Tokyo, Hong Kong:
World Health Organization; 1989.
3. Turnbull RB, Kyle K, Watson FR, Spratt J. Cancer of the
Colon: The Influence of the No-Touch Isolation Technique on
Survival Rates. Ann Surg 1967; 166:420-7.
4. Gebski V, Leung O, McNeil D, Linn D. SPIDA User's Manual.
Version 6. New South Wales, Australia: Statistical Computing
Laboratory, Macquarie University; 1992.
5. Segi M. Cancer mortality for selected sites in 24 countries
(1950-57). Sendai, Japan: Department of Public Health,
Tohoku University School of Medicine; 1960.
6. Cancer Incidence in Five Continents. Volume VI. Parkin DM,
Muir CS, Whelan SL, Gao YT, Ferlay J, Powell J, eds. IARC
Scientific Publications No. 120. Lyon: International Agency for
Research on Cancer; 1992: pp 924-5.
7. Hakulinien T, Andersen AA, Malker B, Pukkala E, Schou G,
Tblinius H. Trends in Cancer Incidence in the Nordic
Countries. A Collaborative Study of the Five Nordic Cancer
Registries. Acta Pathol Microbiol Immunol Scand (A ) 1986;
94/Suppl 288: pp 42-5.
8. Cancer in the Nordic Countries. Bullettin of the Association of
the Nordic Cancer Registries (ANCR). Helsinki: ANCR; 1999:
pp 6,14.
9. Chapuis PH, Newland RC, Macpherson JG, Dent O, Payne JE,
Pheils MT. The Distribution of Colorectal Carcinoma and the
Relationship of Tumour Site to the Survival of Patients
Following Resection. Aust NZ J Surg 1981; 51:127-31.
10. Aldrich MC, Phillips RKS, Hittinger R, Fry JS, Fielding LP.
Influence of tumour site on presentation, management and
subsequent outcome in large bowel cancer. Br J Surg 1986; 73:
663-70.
11. Abrams JS, Reines HD. Increasing Incidence of Right-Sided
Lesions in Colorectal Cancer. Am J Surg 1979; 137:522-6.
12. Slater GI, Haber RH, Aufses AH. Changing Distribution of
Carcinoma of the Colon and Rectum. Surg Gynecol Obstet
1984; 158:216-8.
13. Cady B, Stone MD, Wayne J. Continuing Trends in the
Prevalence of Right-Sided Lesions Among Colorectal
Carcinomas. Arch Surg 1993; 128: 505-9.
14. Secco GB, Fardelli R, Campora E, Lapertosa G, Gentile R.
Zoli S, et al. Primary Mucinous Adenocarcinomas and Signet-
Ring Cell Carcinomas of Colon and Rectum. Oncology 1994;
51: 30-4.
15. Minsky BD. Clinicopathologic Impact of Colloid in Colorectal
Carcinoma. Dis Colon Rectum 1990; 33:714-9.
16. Yamamoto S, Mochizuki H, Hase K, Yamamoto T, Ohkusa Y,
Yokoyama S, et al. Assessment of Clinicopathologic Features
of Colorectal Mucinous Adenocarcinoma. Am J Surg 1993;
166:257-61.
17. Tung S-Y, Wu C-S, Chen P-C. Primary Signet Ring Cell
Carcinoma of Colorectum: An Age- and Sex-Matched
Controlled Study. Am J Gastroenterol 1996; 91:2195-9.
18. Rognum TO, Lund E, Meling GI, Langmark F. Near Diploid
Large Bowel Carcinomas Have Better Five-Year Survival
Than Aneuploid Ones. Cancer 1991; 68:1077-81.
19. Jarvinen HJ, Ovaska J, Mecklin J-P. Improvements in the
treatment and prognosis of colorectal carcinoma. Br J Surg
1988; 75: 25-7.
20. Lichtman SM, Mandel F, Hoexter B, Goldman IS, Budman
DR, Labow S, et al. Prospective Analysis of Colorectal
Carcinoma. Determination of an Age-Site and Stage
Relationship and the Correlation of DNA Index with
Clinicopathologic Parameters. Dis Colon Rectum 1994; 37:
1286-90.
21. Cappell MS, Goldberg ES. The Relationship Between the
Clinical Presentation and Spread of Colon Cancer in 315
Consecutive Patients. A Significant Trend of Earlier Cancer
Detection from 1982 through 1988 at a University Hospital. J
Clin Gastroenterol 1992; 14: 227-35.
22. Mulcahy HE, Patchett SE, Daly L, OTJonoghue PD. Prognosis
of elderly patients with large bowel cancer. Br J Surg 1994; 81:
736-8.
23. Van Der Stappen JWJ, Hendriks T, Wobbes T. Correlation
Between Collagenolytic Activity and Grade of Histological
Differentiation in Colorectal TUmors. Int J Cancer 1990; 45:
1071-8.
24. Wu C-S, Tung S-Y, Chen P-C, Kuo Y-C. Alimentary Tract and
Pancreas. Clinicopathological study of colorectal mucinous
carcinoma in Taiwan: a multivariate analysis. J Gastroenterol
Hepatol 1996;11:77-81.
25. Mitmaker B, Begin LR, Gordon PH. Nuclear Shape as a
Prognostic Discriminant in Colorectal Carcinoma. Dis Colon
Rectum 1991; 34:249-59.
26. Newland RC, Dent OF, Lyttle MNB, Chapuis PH, Bokey EL.
Pathologic Determinants of Survival Associated with
Colorectal Cancer with Lymph Node Metastases. A
Multivatiate Analysis of 579 Patients. Cancer 1994; 73:2076-82.
Læknablaðið 2001/87 117