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Læknablaðið - 15.02.2001, Qupperneq 21

Læknablaðið - 15.02.2001, Qupperneq 21
FRÆÐIGREINAR / RISTILKRABBAMEIN og þroskunargráðu æxla, þannig að æxli í hægri hluta ristils voru á hærra Dukes stigi og verr þroskuð en æxli í vinstri hluta ristils. Aldrich og félagar komust að svipaðri niðurstöðu (10). Þakkir Höfundar þakka Þorgeiri Þorgeirssyni yfirlækni á meinafræðideild Fjórðungssjúkrahúss Akureyrar fyrir aðgang að skriflegum gögnum meinafræði- deildarinnar og vefjasýnum til endurskoðunar. Helgi Sigvaldason fær þakkir fyrir veitta aðstoð við tölfræðiúrvinnslu. Krabbameinsskrá Krabbameins- félags Islands færum við þakkir fyrir upplýsingar um greinda einstaklinga. Vísindasjóður Krabbameinsfélags Islands og Vísindasjóður Landspítalans fá þakkir fyrir styrkveit- ingar til rannsóknarinnar. Heimildir 1. Hamilton SR, Vogelstein B, Kudo S, Riboli E, Nakamura S, Hainaut R Carcinoma of the Colon and Rectum. In: Hamilton SR, Aaltonen LA, eds. Pathology & Genetics of Tumours of the Digestive System. Lyon: IACR Press; 2000: pp 105. 2. 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Near Diploid Large Bowel Carcinomas Have Better Five-Year Survival Than Aneuploid Ones. Cancer 1991; 68:1077-81. 19. Jarvinen HJ, Ovaska J, Mecklin J-P. Improvements in the treatment and prognosis of colorectal carcinoma. Br J Surg 1988; 75: 25-7. 20. Lichtman SM, Mandel F, Hoexter B, Goldman IS, Budman DR, Labow S, et al. Prospective Analysis of Colorectal Carcinoma. Determination of an Age-Site and Stage Relationship and the Correlation of DNA Index with Clinicopathologic Parameters. Dis Colon Rectum 1994; 37: 1286-90. 21. Cappell MS, Goldberg ES. The Relationship Between the Clinical Presentation and Spread of Colon Cancer in 315 Consecutive Patients. A Significant Trend of Earlier Cancer Detection from 1982 through 1988 at a University Hospital. J Clin Gastroenterol 1992; 14: 227-35. 22. Mulcahy HE, Patchett SE, Daly L, OTJonoghue PD. Prognosis of elderly patients with large bowel cancer. Br J Surg 1994; 81: 736-8. 23. Van Der Stappen JWJ, Hendriks T, Wobbes T. Correlation Between Collagenolytic Activity and Grade of Histological Differentiation in Colorectal TUmors. Int J Cancer 1990; 45: 1071-8. 24. Wu C-S, Tung S-Y, Chen P-C, Kuo Y-C. Alimentary Tract and Pancreas. Clinicopathological study of colorectal mucinous carcinoma in Taiwan: a multivariate analysis. J Gastroenterol Hepatol 1996;11:77-81. 25. Mitmaker B, Begin LR, Gordon PH. Nuclear Shape as a Prognostic Discriminant in Colorectal Carcinoma. Dis Colon Rectum 1991; 34:249-59. 26. Newland RC, Dent OF, Lyttle MNB, Chapuis PH, Bokey EL. Pathologic Determinants of Survival Associated with Colorectal Cancer with Lymph Node Metastases. A Multivatiate Analysis of 579 Patients. Cancer 1994; 73:2076-82. Læknablaðið 2001/87 117
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