Læknablaðið : fylgirit - 01.12.1983, Page 37

Læknablaðið : fylgirit - 01.12.1983, Page 37
35 Stða 3 fyrir sjúklrng: 1111 Dagsetn.:___________________________Rannsakandi: Tegund Einkenni Ekki metrð Stig seinustu (sjá leiðarv.) Til staðar Vegna 2 lyfja Geölag Minnkuð einbeitmgargeta Þreyta og minnkað útfiald Svfia - kyrrð (sedation) Minnistruflanir tunglyndi Kvlði - 6tti Svefn aukinn □ minnkaður □ Diaumar aukmr n mtnnkaðirn Geðran flkn fri taugakerfi Dystoni Stirðleiki Dyskinesis/hyperkinesis Titnnqur Vöóvaðrði (akatisi) Kiairrar oq floq Dofatilfinning Osjilfráð Akkcrodat lonstruf lanir Munnvatmsrenns! i aukiðri minnkaðu Ogleði / uppköst Niðurqanqur □ Maqðatreqða□ Erfiðleikar við pvaolát Mikil þvaqlát / mikill þorsti Svimi við að ilsa á f*t ur Hiartsláttur Aukinn sviti Onnur Ef um enn önnur ein- 9eta þeirra á naslu slðu Húðútbrot (nánar) 3 a □ b a c n d a Kiáði Ljösviðkvastni Húðlitur aukinn l l minnkaði* [J Pynqd aukinTI minnkuð □ Tlðablmðinqar auknarl! fart tar I 1 Vökvi úr br jðsttmMGynrkaTust : 1 1 Kynhvöt aukinÖ^ minnkuðn Truflun á erektion Truflun á sáðláti Truflun á kynfullnaqinqu Minnkuð vaqinal secretlon Höfuðverkur Llkamleq flkn zn 1 p = pericdiskt k * samfellt (sjá leiðarvtsi) 2 o * ósennilegt t * vafasaml s = sennilegt 3 a » nuslingaltkt b • aðasprengingar c » urticaria d » psoriasisltk Vonandi tekst okkur meö skipulögðum rann- sóknum og nákvæmu klínísku eftirliti að halda aukaverkunum geðlyfja í algjöru lágmarki og fyrirbyggja, að meira eða minna óbætanlegar aukaverkanir eins og T.D. nái að þróast. Einnig þarf að veita fjölmiðlum hlutlausar upplýsingar um geðlyfjameðferð, kosti hennar og annmarka, þannig að almenningur láti ekki blindast af ein- litum og ófaglegum áróðri gegn þessu mikilvæga og ómissandi meðferðartæki í baráttunni við geðsjúk- dóma. SUMMARY Side-effects of psychoactive drugs. On the initiative of the Scandinavian Psychopharma- cological Association an investigation of psychopharma- cological side-effects was performed at the State Psychiatric clinics in Reykjavík on the 22nd and 23rd of February 1982. A special questionnaire was developed for this purpose, which is described in this paper. This study was a part of a Scandinavian prevalence study of side effects of psychopharmaca. The data results from all the Scandinavian countries including Iceland were collected in Uppsala Sweden for statistical analysis. A preliminary analysis of the Icelandic material was carried out shortly after the investigation in order to get some information about the frequency of side-effects in Iceland as soon as possible. These results are presented in this paper. The study implies almost the same frequency of side-effects in Iceland as in other western countries, yet with one important exception. The frequency of drug induced tardive dyskinesia seems to be much lower in Iceland than in most other countries. The possible explanations of this fact are discussed. The im- portance of good clinical care and judicious admini- stration of psychopharmaca keeping side-effects at absolute minium is emphasized. HEIMILDIR 1. Delay, J., Deniker P. et Harl, J.-H. Traitement des états d'excitation et d'agitation par une methode médicamenteuse dérivée de l’hibernothérapie. Ann.méd.-psychol. 1952, 110,267-73. 2. Ravn, J., Truxal, ein neuartiges Psychopharmakon. Wien, Klin. Wschr. 1960, 72, 192-6. 3. Denber, H.C.B., Florio, D. and Rajotte. P. Third evaluation of Haloperidol. Amer. J. Psychiat. 1962, 119, 172-3. 4. Laduron, P. Pimozide (Orap): Metabolism and interaction with cerebral amines. Clin. trials J., Supp. II. 1971, 19-24. 5. Kuhn, R. Úber die Behandlung depressiver Zustánde mit einem Iminodibenzylderivat (G. 22355). Schw. med Wschr. 1957,87,1135-40. 6. Crane, G.E. Persistent dyskinesia. Br. J. Psychiat. 1973, 122,395-405. 7. Lingjærde, O. Psykofarmaka 2. rev. uth. Tanum-Norli Oslo 1976. 8. Jeste, D.V. and Wyatt, R.J. Therpeutic strategies against Tardive Dyskinesia. 1982, 9, 803. 9. Gerlach, J. Komplikationer ved langtids- behandling med neuroleptica, spec. tardive dyskinesier. Symposium for danske psykiatera 27. februar 1981. H. Lundbeck & co. A/S Köbenhavn 1981,28-9.
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