Læknaneminn - 01.04.1994, Side 27

Læknaneminn - 01.04.1994, Side 27
í einstaka tilvikum hverfa meinvörp af sjálfu sér (spontan regression) og sjúklingarnir lifa í mörg ár frá greiningu. Þetta er hins vegar sjaldgæft (< 1% tilfella) og sést oftast hjá sjúklingum með stök meinvörp í lunga. Er talið að ónæmiskerfið gegni lykilhlutverki í eyðingu þessara meinvarpa. LOKAORÐ Síðustu tvo áratugi hafa lífshorfur sjúklinga með nýmafrumukrabbamein á Islandi verið sambærilegar við það sem best þekkist erlendis. Lífshorfur hafa hins vegar staðið í stað áþessu tímabili (3). Til þess að bæta horfur þessara sjúklinga þarf að greina sjúklinga fyrr og á lægri stigum. Læknar og læknanemar þurfa að þekkja betur einkenni nýrnafrumukrabbameins og vanda þarf til uppvinnslu á blóðmigu. Einnig er Ijóst að bæta þarf meðferð sjúklinga með meinvörp en horfur þeirra eru mjög slæmar í dag, jafnt hér á landi sem erlendis. Þakkir: SérstakarþakkirfærEngiIbertSigurðsson læknir fyrir yfirlestur greinarinnar og þarfar ábendingar. 0 HEIMILDIR 1. Upplýsingar úr Krabbameinsskrá K.I. Skýrsla Krabbameinsfélags Islands, Reykjavík 1993. 2. Muir C, et al. Cancer incidence in five continents, V. Intemational agency for reserarch on cancer. WHO, Lyon, 1987. 3. Tómas Guðbjartsson, Guðmundur V. Einarsson, Jónas Magnússon. Nýrnafrumukrabbamein á íslandi 1971- 1990. Greining og lífshorfur. - Klínísk rannsókn á 408 tilfellum -. (Bíður birtingar í Læknablaðinu). 4. Dayal H, Kinman J. Epidemiology of kidney cancer. Seminars in Oncology 1983; 10(4); 366-377. 5. Reese JH, et al. Renal cell carcinoma. Current Science 1992; 427-434. 6. Cronin ER. Southwestem internal medicine conference: Renal cell carcinoma. The American Joumal ofthe Medical Sciences 1991; 302, No: 4, (Oct.): 249-259. 7. Grawitz P. Die sogenannten Lipoma der Niere, Virchow Arch. Pathol. Anat. 1883;93: 39. 8. Tanagho E, etal. Smith's General Urology. 13. útg. Lange, 1992. 9. Jacqmin D, et al. Multiple tumors in the same kidney: Incidence and therapeutic implications. EurUrology 1992; 21: 32-34. 10. Skinner DG, et al. Diagnosis and management of renal cell carcinoma. Cancer 1971; 28 (Nov.): 1165- 1177. 11. Holland JM. Cancer of the kidney - Natural history and staging. Cancer 1973; 32(Nov.): 1030-42. 12. Thorhallsson P, Tulinius H. Tumors in Iceland: 3. Malignant tumours of kidney. A histological classification. Acta Path Microbiol Scand (Sect. A) 1981; 89: 403-410. 13. Fairchild T, Dail D, Brannen G. Renal oncocytoma - bilateral, multifocal. Urology 1983; Vol XXII (No 4): 355-359. 14. Einarsson GV, Njalsson Þ, Eyjolfsson O, Benediktsson H. Oncocytoma renis. Læknablaðið 1985; 71: 246-48. 15. Konnak JW and Grossman HB. Renal cell carcinoma as an incidental ftnding. The Joumal of Urology, 1985, 134(Dec,): 1094-1096. 16. Aso Y. and Homma Y. A survey on incidental renal cell carcinoma in Japan. The Joumal of Urology 1992; 147(Feb.): 340-343. 17. Lupton EW. Diagnostic features in urology: Investigation of malignant disease of the upper urinary tract.(29. kafli) 1991: 435-449. 18. Graham TE, Rockey KE. Renal masses in adults: Differentiating benign from neoplastic causes. Postgraduate Medicine 1990; 87, No: 2 (Feb): 111- 125. 19. Constantinides C, et al. Accuracy of magnetic resonance imaging compared to computerized tomography and renal selective angiography in preoperatively staging renal cell carcinoma. Urol. Int. 1991; 47: 181-185. 20. Robson CJ. Radical nephrectomy for renal cell carcinoma. J Urol.; B) 1963, 37-42. 21. Robson CJ, Churchill BM., Anderson W. The result of radical nephrectomy for renal carcinoma, Journal of Urology 1969; 101: 297-301. 22. Peters P, et al. The role of lymphadenectomy in the management of renal cell carcinoma. Urol Clin North Am 1980; 705-709. 23. Davis B, Weigel J. Management of advanced renal cell carcinoma. AUA update series 1990. Lesson 3, Vol. IX. American Urologic Association. 24. Rosenberg SA, et al. A progression report on the treatment of 157 patients with advanced cancer using lymphokine-activated killer cells and interleukin-2 or high-dose interleukin-2 alone, N Engl J M 1987; 316: 889-897. 25. Provet J, et al. Partial nephrectomy for renal cell carcinoma: Indications, results and implications, The Journal of Urology 1991; 145: 472-476. 26. Mukamel E et al. Incidental small renal tumors accompanying clinically overt renal cell carcinoma. LÆKNANEMINN 1 1994 47. árg. 21
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