Læknaneminn - 01.04.1994, Qupperneq 37
5. Miller FD, Heppner GH. Cellular interactions in
metastasis. Cancer Metastasis Revl990; 9: 21-34.
6. Behrens J, Mareel MM, Van Roy FM, Birchmeier W.
Dissecting tumor cell invasion: Epithelial cells aquire
invasive properties after the loss of uvomorulin-
mediated cell-cell adhesion. J Cell Biol 1989; 108:
2435-2447.
7. Giroldi LA, Schalken JA. Decreased expression of
the intercellular adhesion molecule E-cadherin in
prostate cancer: Biological significance and clinical
implications. Cancer Metastasis Rev 1993; 12: 29-
37.
8. Hedrick L, Cho KR, Vogelstein B. Cell adhesion
molecules as tumour supressors. Trends Cell Biol
1993; 3: 36-38.
9. Grunwald GB. The structural and functional analysis
of cadherin calcium-dependent cell adhesion
molecules. Curr Op Cell Biol 1993; 5: 797-805.
10. Shimoyama Y, Nagafuchi A, Fujita S, Gotoh M, et
al. Cadherin dysfunction in a human cancer cell line:
Possible involvement of loss of a-catenin expression
in reduced cell-cell adhesiveness. Cancer Res 1992;
52: 5770-5774.
11. Morton RA, Ewing CM, Nagafuchi A, Tsukita S, Isaacs
WB. Reduction of E-cadherin levels and deletion of
the a-catenin gene in human prostate cancer cells.
Cancer Res 1993; 53: 3585-3590.
12. Behrens J, Vakaet L, Friis R, Winterhager E, et al.
Loss of epithelial differentiation and Gain of
invasiveness correlates with tyrosin phophorylation
of the E-cadherin/p-catenin complex in cells
transformed with a temperature-sensitive v-SRC
gene. J Cell Biol 1993; 120,3: 757-766.
13. Shimoyama Y, Hirohashi S, Hirano S, et al.
Cadherin cell-adhesion molecules in human
epithelial tissues and carcinoma. Cancer Res 1989;
49: 2128-2133.
14. Nose A, Takeichi M. A novel cadherin cell adhesion
molecule: its expression pattems associated with
implantation and organogenesis of mouse embryos.
J Cell Biol 1986; 103: 2649-2658.
15. TakeichiM. Cadherins in cancer: implications for
invasion and metastasis. Curr op Cell Biol 1993; 5:
806-811.
16. Ögmundsdóttir HM. Þegar frumumar ganga í
barndóm. Læknaneminn 1991; 2: 55-62.
17. Kinsella AR, Green B, Lepts GC, Hill CL, et al. The
role of cell-cell adhesion molecule E-cadherin in
large bowel tumour cell invasion and metastasis. Br
JCancer 1993; 67: 904-909.
18. Geiger B, Ayalon O. Cadherins. Ann Rev Cell Biol
1992; 8: 307-332.
19. Alberts B, Bray D, Lewis J, Raff M, et al. Molecular
biology of the cell, second edition, New York &
London; Garland Publishing, Inc. 1989: 940-941.
20. Takeichi M. Cadherin cell adhesion receptors as a
LÆKNANEMINN 1 1994 47. árg.
morphogenetic regulator. Science 1991; 251:1451-
1455.
21. Frixen UH, Behrens J, Sachs M, Eberle G, et al. E-
cadherin-mediated cell-cell adhesion prevents
invasiveness of human carcinoma cells. J Cell Biol
1991; 113, 1: 173-185.
22. Bracke ME, Vyncke BM, Bruyneel EA, et al.
Insulin-like growth factor I activates the invasion
suppressor function of E-cadherin in MCF-7 human
mammary carcinoma cells invitro. BJC 1993; 68,
2: 282-289.
23. Morson BC, Dawson IM. Gastrointestinal
Pathology, 2nd edition 1979; Blackwell, London.
24. Umbas R, Schalken JA, Aalders TW, Carter BS, et
al. Expression of the cellular adhesion molecule E-
cadherin is reduced or absent in high-grade prostate
cancer. CancerRes 1992; 52: 5104-5109.
25. Marx J. Cellular changes.on the route to metastasis.
Science 1993; 259: 626-629.
26. Shimoyama Y, Hirohashi S. Expression of E-and P-
cadherin in Gastric Carcinomas. Cancer Res 1991;
51: 2185-2192.
27. Oka H, Shiozaki H, Kobayashi K, et al. Expression
of E-cadherin cell adhesion molecules in human
breast cancer tissues and its relationship to
metastasis. Cancer Res 1993; 53: 1696-1701.
28. Moll R, Mitze M, Frixen UH, Birchmeier W.
Differential loss of E-cadherin expression in
infiltrating ductal and lobular breast carcinomas.
Arn J Path (í prentun).
29. Gamallo C, Palacios J, Suarez A, et al. Correlation
of E-cadherin expression with differentiation grade
and histological type in breast carcinoma. Am J Path
1993; vol.142, no.4: 987-993.
30. Van Roy, Mareel M. Tumour invasion: effects of
cell adhesion and motility. Trends Cell Biol 1992; 2:
163-169.
31. Krueger J, Ray A, Tamm I, Sehgal PB. Expression
and function of interleukin-6 in epithelial cells. J
Cell Biochem 1991; 45: 327-334.
32. Dorudi S, Sheffield J, Poulsom R, Northover JMA,
Hart IR. E-cadherin expression in colorectal cancer.
An immunocytochemical and in situ hybridization
study. Am J Path 1993; vol.142, no.4: 981-986.
33. Vleminckx K, Vakaet Jr L, Mareel M, Fiers W, Van
Roy F. Genetic manipulation of E-cadherin
expression by epithelial tumor cells reveals an
invasion suppressor role. Cell 1991; 66: 107-119.
34. Harris LL, Hollstein M. Clinical implications of the
p53 tumor-suppressor gene. NEJMAG 1993; 329,
18: 1318-1327.
35. Cleton-Jansen AM, Moerland EW, Kuipers-
Dijkshoorn NJ, Callen DF, et al. At least two
different regions are involved in allelic imbalance on
chromosome arm 16q in breast cancer. Genes,
chromosomes & cancer (í prentun).
31